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Development and validation of a model incorporating choroid plexus morphology from brain MRI to predict anti-TNF-α therapy outcomes in Crohn's disease.

Overview

Authors: Mengting Huang1,2, Shuo Huang1,2, Qinyue Luo1,2, Yuting Zheng1,2, Hanting Li1,2, Ping Han1,2, Liangru Zhu3, Heshui Shi1,2
  1. Department of Radiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology,NO.1277 Jiefang Avenue, Wuhan, Hubei Province 430022 China
  2. Hubei Province Key Laboratory of Molecular Imaging,Wuhan, 430022 China
  3. Division of Gastroenterology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology,Wuhan, China
Journal: BMC gastroenterology, volume 26, issue 1, article 232
Dates: received 15 September 2024; accepted 2 March 2026; published online 6 March 2026
Type: Research article · Language: English
License: CC BY-NC-ND
Identifiers: DOI 10.1186/s12876-026-04720-w · PMID 41787284 · PMCID PMC13078057 · OpenAlex W7133869361
Open access: gold, a free copy (OpenAlex)
Status: code on request
Categories: structural MRI / diffusion (modality), human (organism), clinical / translational (subfield)
Methods: Connectivity, Spectral & time-frequency, Statistics, Machine learning, fMRI & imaging
Keywords: Crohn’s disease, Prognostic factor, Neuroimaging, Brain-gut axis, Choroid plexus
MeSH: Choroid Plexus*, Crohn Disease*, Magnetic Resonance Imaging*, Adalimumab, Adult, Brain, Female, Humans, Infliximab, Male, Middle Aged, Predictive Value of Tests, Prospective Studies, Treatment Outcome, Tumor Necrosis Factor-alpha (* major topic)
Topic: Inflammatory Bowel Disease (Genetics, Biochemistry, Genetics and Molecular Biology), according to OpenAlex
Citations: not cited yet (Europe PMC); 41 references in the paper

Abstract

The abstract is not reproduced here: the paper's license (CC BY-NC-ND) does not allow it. Read it in the paper, at the publisher or on Europe PMC.

Code

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Data

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Code and data availability statement

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  • it says that the code is available on request

Read it in the paper: doi.org/10.1186/s12876-026-04720-w.

Versions

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Version 1, 30 September 2026: the first record

Recorded: type, language, journal, volume, issue, pages, dates, 8 authors, 5 keywords, 15 MeSH terms, 1 funder, 41 references.

Cite

This paper

Huang, M., Huang, S., Luo, Q., Zheng, Y., Li, H., Han, P., Zhu, L., & Shi, H. (2026). Development and validation of a model incorporating choroid plexus morphology from brain MRI to predict anti-TNF-α therapy outcomes in Crohn's disease. BMC gastroenterology, 26(1), 232. https://doi.org/10.1186/s12876-026-04720-w

BibTeX

@article{huang2026development,
author = {Huang, Mengting and Huang, Shuo and Luo, Qinyue and Zheng, Yuting and Li, Hanting and Han, Ping and Zhu, Liangru and Shi, Heshui},
title = {{Development and validation of a model incorporating choroid plexus morphology from brain MRI to predict anti-TNF-α therapy outcomes in Crohn's disease}},
journal = {BMC gastroenterology},
year = {2026},
month = mar,
volume = {26},
number = {1},
pages = {232},
publisher = {BMC},
issn = {1471-230X},
doi = {10.1186/s12876-026-04720-w},
url = {https://doi.org/10.1186/s12876-026-04720-w},
pmid = {41787284},
pmcid = {PMC13078057}
}

RIS

TY - JOUR
AU - Huang, Mengting
AU - Huang, Shuo
AU - Luo, Qinyue
AU - Zheng, Yuting
AU - Li, Hanting
AU - Han, Ping
AU - Zhu, Liangru
AU - Shi, Heshui
TI - Development and validation of a model incorporating choroid plexus morphology from brain MRI to predict anti-TNF-α therapy outcomes in Crohn's disease
T2 - BMC gastroenterology
J2 - BMC Gastroenterol
PY - 2026
DA - 2026/03/06
VL - 26
IS - 1
SP - 232
SN - 1471-230X
PB - BMC
DO - 10.1186/s12876-026-04720-w
UR - https://doi.org/10.1186/s12876-026-04720-w
LA - en
ER -

CSL-JSON

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"container-title": "BMC gastroenterology",
"author": [
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"publisher": "BMC",
"URL": "https://doi.org/10.1186/s12876-026-04720-w",
"language": "en",
"issued": {
"date-parts": [
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}

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