OSCR

Dynamics of neutrophilia at the neurovascular unit arising from repeated pulmonary inflammation.

Overview

Authors: Wesley Chiang1,2,3, Herman Li1,4, Linh Le4, Jennifer David-Bercholz5, Ana I. Caceres5, Danial Ahmad6, Erica Squire1,4, Kamryn S. Stecyk1, Mariah Marrero4, Amanda Pereira1, Rene Squire1, Claire Lim4, James L. McGrath6, Ania K. Majewska4, Niccolò Terrando5,7,8, Harris A. Gelbard1,4,9,10,11
ORCID iDs: Herman Li
  1. Center for Neurotherapeutics Discovery, University of Rochester Medical Center,Rochester, NY USA
  2. Departmentof Biochemistry and Biophysics, University of Rochester Medical Center,Rochester, NY USA
  3. Department of Chemistry, University of Rochester,Rochester, NY USA
  4. Departmentof Neuroscience, University of Rochester Medical Center,Rochester, NY USA
  5. Department of Anesthesiology, Duke University Medical Center,Durham, NC USA
  6. Department of Biomedical Engineering, University of Rochester,Rochester, NY USA
  7. Department of Cell Biology, Duke University Medical Center,Durham, NC USA
  8. Department of Integrative Immunobiology, Duke University Medical Center,Durham, NC USA
  9. Departmentof Neurology, University of Rochester Medical Center,Rochester, NY USA
  10. Departmentof Immunology, Microbiology, and Virology, University of Rochester Medical Center,Rochester, NY USA
  11. Departmentof Pediatrics, University of Rochester Medical Center,Rochester, NY USA
Institutions: University of Rochester Medicine (United States); University of Rochester (United States); Duke Medical Center (United States)
Journal: Journal of neuroinflammation, volume 23, issue 1, article 148
Dates: received 3 September 2025; accepted 10 March 2026; published online 25 March 2026
Type: Research article · Language: English
License: CC BY-NC-ND
Identifiers: DOI 10.1186/s12974-026-03771-w · PMID 41882669 · PMCID PMC13137501 · OpenAlex W7140319483
Open access: gold, a free copy (OpenAlex)
Status: data only (how the code is found and verified)
Categories: histology / microscopy (modality), optical imaging (calcium, voltage, 2-photon) (modality), human (organism), mouse (organism), cellular / molecular (subfield)
Methods: Statistics
Keywords: Lung injury, LPS, Neutrophilia, Intranasal, Hippocampus, 2-photon, Neuroimmunology, Lung-brain axis
MeSH: Brain*, Neutrophils*, Pneumonia*, Animals, Humans, Lipopolysaccharides, Male, Mice, Mice, Inbred C57BL (* major topic)
Topic: Neuroinflammation and Neurodegeneration Mechanisms (Neurology, Neuroscience), according to OpenAlex
Funding: National Institute of General Medical Sciences,United States (T32GM135134); National Institute on Aging (T32AG076455, RF1AG079138); HHS | NIH | National Institute of Neurological Disorders and Stroke (NINDS) (R01NS114480); Alzheimer's Association (AARG-NTF-19-619116)
Citations: cited by 1 paper (Europe PMC); 95 references in the paper

Abstract

The abstract is not reproduced here: the paper's license (CC BY-NC-ND) does not allow it. Read it in the paper, at the publisher or on Europe PMC.

Code

The paper links to its data and to no code of its authors: see the Data section.

Tracing map

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Data

Datasets cited

Data availability statement

The paper has a data availability statement. Its license (CC BY-NC-ND) does not allow reproducing it here; in short, from what the harvester recognized in it:

Read it in the paper: doi.org/10.1186/s12974-026-03771-w.

Versions

The history of this record: each version stored by the harvester or made by a correction of its authors or of the maintainers of its code, and what changed in its facts. The texts of the paper (its abstract, its availability statements) are not part of it; versions that changed only those are not listed.

Version 1, 30 September 2026: the first record

Recorded: type, language, journal, volume, issue, pages, dates, 16 authors, 8 keywords, 9 MeSH terms, 4 funders, 91 references.

Cite

This paper

Chiang, W., Li, H., Le, L., David-Bercholz, J., Caceres, A. I., Ahmad, D., Squire, E., Stecyk, K. S., Marrero, M., Pereira, A., Squire, R., Lim, C., McGrath, J. L., Majewska, A. K., Terrando, N., & Gelbard, H. A. (2026). Dynamics of neutrophilia at the neurovascular unit arising from repeated pulmonary inflammation. Journal of neuroinflammation, 23(1), 148. https://doi.org/10.1186/s12974-026-03771-w

BibTeX

@article{chiang2026dynamics,
author = {Chiang, Wesley and Li, Herman and Le, Linh and David-Bercholz, Jennifer and Caceres, Ana I. and Ahmad, Danial and Squire, Erica and Stecyk, Kamryn S. and Marrero, Mariah and Pereira, Amanda and Squire, Rene and Lim, Claire and McGrath, James L. and Majewska, Ania K. and Terrando, Niccolò and Gelbard, Harris A.},
title = {{Dynamics of neutrophilia at the neurovascular unit arising from repeated pulmonary inflammation}},
journal = {Journal of neuroinflammation},
year = {2026},
month = mar,
volume = {23},
number = {1},
pages = {148},
publisher = {BMC},
issn = {1742-2094},
doi = {10.1186/s12974-026-03771-w},
url = {https://doi.org/10.1186/s12974-026-03771-w},
pmid = {41882669},
pmcid = {PMC13137501}
}

RIS

TY - JOUR
AU - Chiang, Wesley
AU - Li, Herman
AU - Le, Linh
AU - David-Bercholz, Jennifer
AU - Caceres, Ana I.
AU - Ahmad, Danial
AU - Squire, Erica
AU - Stecyk, Kamryn S.
AU - Marrero, Mariah
AU - Pereira, Amanda
AU - Squire, Rene
AU - Lim, Claire
AU - McGrath, James L.
AU - Majewska, Ania K.
AU - Terrando, Niccolò
AU - Gelbard, Harris A.
TI - Dynamics of neutrophilia at the neurovascular unit arising from repeated pulmonary inflammation
T2 - Journal of neuroinflammation
J2 - J Neuroinflammation
PY - 2026
DA - 2026/03/25
VL - 23
IS - 1
SP - 148
SN - 1742-2094
PB - BMC
DO - 10.1186/s12974-026-03771-w
UR - https://doi.org/10.1186/s12974-026-03771-w
LA - en
ER -

CSL-JSON

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"issued": {
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