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Gordonibacter-associated regulatory T cell dysfunction and S100A11-mediated neural impairment in Hirschsprung's disease: a microbiota-immune-neural axis.

Overview

Authors: Ting Yao1, Meili Fan1, Zenghui Hao1, Zaiqun Jiang1, Xu Li1, Shuyu Wang2, Zhilin Xu1
ORCID iDs: Ting Yao, Zenghui Hao, Shuyu Wang, Zhilin Xu
  1. Department of Pediatric Surgery, The Sixth Affiliated Hospital of Harbin Medical University, Aiying Street 998, Songbei District, Harbin, 150028 Heilongjiang People’s Republic of China
  2. Department of Neurology, The First Affiliated Hospital of Harbin Medical University, Youzheng Street 223, Nanggang District, Harbin, 150023 Heilongjiang People’s Republic of China
Institutions: Harbin Medical University (China); First Affiliated Hospital of Harbin Medical University (China)
Journal: Cell & bioscience, volume 16, issue 1, article 56
Dates: received 9 November 2025; accepted 8 March 2026; published online 3 April 2026
Type: Research article · Language: English
License: CC BY-NC-ND
Identifiers: DOI 10.1186/s13578-026-01562-7 · PMID 41933371 · PMCID PMC13173780 · OpenAlex W7149008468
Open access: gold, a free copy (OpenAlex)
Status: data only
Categories: genetics / omics (modality), cellular / molecular (subfield)
Keywords: Hirschsprung's disease, Gut microbiota, Mendelian randomization, Immune cells, S100A11, Enteric nervous system
Topic: Congenital gastrointestinal and neural anomalies (Surgery, Medicine), according to OpenAlex
Funding: Pediatric Special Project of the Sixth Affiliated Hospital of Harbin Medical University (24ZX008); Key Project of the Joint Fund of the Natural Science Foundation of Heilongjiang Province (ZL2024H001); Natural Science Foundation of Heilongjiang Province (PL2024H140)
Citations: not cited yet (Europe PMC); 37 references in the paper

Abstract

The abstract is not reproduced here: the paper's license (CC BY-NC-ND) does not allow it. Read it in the paper, at the publisher or on Europe PMC.

Code

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Data

Datasets cited

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Data availability statement

The paper has a data availability statement. Its license (CC BY-NC-ND) does not allow reproducing it here; in short, from what the harvester recognized in it:

  • it points to 2 datasets: NCBI, NCBI GEO GSE95502
  • it says that the data are available on request

Read it in the paper: doi.org/10.1186/s13578-026-01562-7.

Versions

The history of this record: each version stored by the harvester or made by a correction of its authors or of the maintainers of its code, and what changed in its facts. The texts of the paper (its abstract, its availability statements) are not part of it; versions that changed only those are not listed.

Version 1, 28 September 2026: the first record

Recorded: type, language, journal, volume, issue, pages, dates, 7 authors, 6 keywords, 3 funders, 37 references.

Cite

This paper

Yao, T., Fan, M., Hao, Z., Jiang, Z., Li, X., Wang, S., & Xu, Z. (2026). Gordonibacter-associated regulatory T cell dysfunction and S100A11-mediated neural impairment in Hirschsprung's disease: a microbiota-immune-neural axis. Cell & bioscience, 16(1), 56. https://doi.org/10.1186/s13578-026-01562-7

BibTeX

@article{yao2026gordonibacter,
author = {Yao, Ting and Fan, Meili and Hao, Zenghui and Jiang, Zaiqun and Li, Xu and Wang, Shuyu and Xu, Zhilin},
title = {{Gordonibacter-associated regulatory T cell dysfunction and S100A11-mediated neural impairment in Hirschsprung's disease: a microbiota-immune-neural axis}},
journal = {Cell \& bioscience},
year = {2026},
month = apr,
volume = {16},
number = {1},
pages = {56},
publisher = {BMC},
issn = {2045-3701},
doi = {10.1186/s13578-026-01562-7},
url = {https://doi.org/10.1186/s13578-026-01562-7},
pmid = {41933371},
pmcid = {PMC13173780}
}

RIS

TY - JOUR
AU - Yao, Ting
AU - Fan, Meili
AU - Hao, Zenghui
AU - Jiang, Zaiqun
AU - Li, Xu
AU - Wang, Shuyu
AU - Xu, Zhilin
TI - Gordonibacter-associated regulatory T cell dysfunction and S100A11-mediated neural impairment in Hirschsprung's disease: a microbiota-immune-neural axis
T2 - Cell & bioscience
J2 - Cell Biosci
PY - 2026
DA - 2026/04/03
VL - 16
IS - 1
SP - 56
SN - 2045-3701
PB - BMC
DO - 10.1186/s13578-026-01562-7
UR - https://doi.org/10.1186/s13578-026-01562-7
LA - en
ER -

CSL-JSON

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"container-title": "Cell & bioscience",
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"language": "en",
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