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A Cloud-Aware Scalable Architecture for Distributed Edge-Enabled BCI Biosensor System.

Overview

Authors: Sayantan Ghosh1,2, Raghavan Bhuvanakantham3,4, Padmanabhan Sindhujaa5, Purushothaman Bhuvana Harishita4, Anand Mohan3, Balázs Gulyás3,6, Domokos Máthé1, Parasuraman Padmanabhan3,4
  1. Department of Biophysics and Radiation Biology, Semmelweis University, 1085 Budapest, Hungary
  2. Department of Integrative Biology, Vellore Institute of Technology, Vellore 632014, India
  3. Cognitive Neuroimaging Centre, Experimental Medicine, Nanyang Technological University, Singapore 636921, Singapore
  4. Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore 636921, Singapore
  5. Faculty of Medicine, PSG Institute of Medical Sciences & Research, Peelamedu, Coimbatore 641004, India
  6. Department of Clinical Neuroscience, Karolinska Institute, 17176 Stockholm, Sweden
Journal: Biosensors, volume 16, issue 3, article 157
Dates: received 31 December 2025; accepted 10 March 2026; published online 13 March 2026
Type: Research article · Language: English
License: CC BY
Identifiers: DOI 10.3390/bios16030157 · PMID 41892049 · PMCID PMC13024191 · OpenAlex W7135228370
Open access: gold, a free copy (OpenAlex)
Status: data only
Categories: EEG (modality), human (organism), methods / tools (subfield)
Methods: Spectral & time-frequency, Preprocessing, Smoothing, state filtering, decompositions, Machine learning, Graphs, Physiology & signal measures, Connectivity
Keywords: Multimodal Brain–Computer Interface, biosensors, EEG, EMG, data processing, edge computing, cloud analytics, electrophysiological signals, real-time signal analysis, scalable data storage, remote health monitoring, continuous biosignal telemetry
MeSH: Biosensing Techniques*, Brain-Computer Interfaces*, Cloud Computing*, Humans, Signal Processing, Computer-Assisted (* major topic)
Topic: EEG and Brain-Computer Interfaces (Cognitive Neuroscience, Neuroscience), according to OpenAlex
Funding: Government of Hungary (National Research, Development and Innovation Office) (RGH-151414)
Citations: cited by 1 paper (Europe PMC); 99 references in the paper

Abstract

BCI biosensors enable continuous monitoring of neural activity, but existing systems face challenges in scalability, latency, and reliable integration with cloud infrastructure. This work presents a cloud-aware, real-time cognitive grid architecture for multimodal BCI biosensors, validated at the system level through a full physical prototype. The system integrates the BioAmp EXG Pill for signal acquisition with an RP2040 microcontroller for local preprocessing using edge-resident TinyML deployment for on-device feature/inference feasibility coupled with environmental context sensors to augment signal context for downstream analytics talking to the external world via Wi-Fi/4G connectivity. A tiered data pipeline was implemented: SD card buffering for raw signals, Redis for near-real-time streaming, PostgreSQL for structured analytics, and AWS S3 with Glacier for long-term archival. End-to-end validation demonstrated consistent edge-level inference with bounded latency, while cloud-assisted telemetry and analytics exhibited variable transmission and processing delays consistent with cellular connectivity and serverless execution characteristics; packet loss remained below 5%. Visualization was achieved through Python 3.10 using Matplotlib GUI, Grafana 10.2.3 dashboards, and on-device LCD displays. Hybrid deployment strategies—local development, simulated cloud testing, and limited cloud usage for benchmark capture—enabled cost-efficient validation while preserving architectural fidelity and latency observability. The results establish a scalable, modular, and energy-efficient biosensor framework, providing a foundation for advanced analytics and translational BCI applications to be explored in subsequent work, with explicit consideration of both edge-resident TinyML inference and cloud-based machine learning workflows.

Reproduced under the paper's license (CC BY), from the paper cited above.

Code

The paper links to its data, not to its authors' code: see the Data section.

Tracing map

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Data

Datasets cited

Data Availability Statement

The data that support the findings of this study are not publicly available as the evaluation dataset comprises proprietary firmware configurations, author-managed cloud infrastructure parameters, and pseudonymized session telemetry logs generated during controlled bench evaluation; access is restricted to protect confidential and proprietary information. These restrictions are of a technical and operational nature and are unrelated to human-subject privacy considerations. The data may be made available upon reasonable request.

Reproduced under the paper's license (CC BY), from the paper cited above.

Versions

The history of this record: each version stored by the harvester or made by a correction of its authors or of the maintainers of its code, and what changed in its facts. The texts of the paper (its abstract, its availability statements) are not part of it; versions that changed only those are not listed.

Version 1, 30 September 2026: the first record

Recorded: type, language, journal, volume, issue, pages, dates, 8 authors, 12 keywords, 5 MeSH terms, 1 funder, 95 references.

Cite

This paper

Ghosh, S., Bhuvanakantham, R., Sindhujaa, P., Harishita, P. B., Mohan, A., Gulyás, B., Máthé, D., & Padmanabhan, P. (2026). A Cloud-Aware Scalable Architecture for Distributed Edge-Enabled BCI Biosensor System. Biosensors, 16(3), 157. https://doi.org/10.3390/bios16030157

BibTeX

@article{ghosh2026cloud,
author = {Ghosh, Sayantan and Bhuvanakantham, Raghavan and Sindhujaa, Padmanabhan and Harishita, Purushothaman Bhuvana and Mohan, Anand and Gulyás, Balázs and Máthé, Domokos and Padmanabhan, Parasuraman},
title = {{A Cloud-Aware Scalable Architecture for Distributed Edge-Enabled BCI Biosensor System}},
journal = {Biosensors},
year = {2026},
month = mar,
volume = {16},
number = {3},
pages = {157},
publisher = {Multidisciplinary Digital Publishing Institute (MDPI)},
issn = {2079-6374},
doi = {10.3390/bios16030157},
url = {https://doi.org/10.3390/bios16030157},
pmid = {41892049},
pmcid = {PMC13024191}
}

RIS

TY - JOUR
AU - Ghosh, Sayantan
AU - Bhuvanakantham, Raghavan
AU - Sindhujaa, Padmanabhan
AU - Harishita, Purushothaman Bhuvana
AU - Mohan, Anand
AU - Gulyás, Balázs
AU - Máthé, Domokos
AU - Padmanabhan, Parasuraman
TI - A Cloud-Aware Scalable Architecture for Distributed Edge-Enabled BCI Biosensor System
T2 - Biosensors
J2 - Biosensors (Basel)
PY - 2026
DA - 2026/03/13
VL - 16
IS - 3
SP - 157
SN - 2079-6374
PB - Multidisciplinary Digital Publishing Institute (MDPI)
DO - 10.3390/bios16030157
UR - https://doi.org/10.3390/bios16030157
LA - en
ER -

CSL-JSON

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