OSCR

Lifestyle and Transcriptional Signatures Associated with Ethnicity/Race-Related Variations in the Functional Connectome.

Code ↔ Paper

14 matches between paragraphs of the paper and lines of its authors' code, computed by the harvester (lexical-v1). Click a colored paragraph or line to see its counterpart.

The 14 matches · 5 of them tie a paragraph to a whole file without given lines: weak matches, whose lines are not tinted
  1. [1] § Results › Ethnicity/race-related variability in brain functional topography and connectome ↔ Code/Split_match/HCP_AA_WA_match_diff.m, lines 1 to 55 · score 0.83 · AA WA, framewise displacement, matched WA, intracranial volume, randomly split, fold · Report a mismatch
  2. [2] § Methods › Defining individual-specific cortical parcellations and the functional connectome ↔ stable_projects/brain_parcellation/Kong2022_ArealMSHBM/step3_generate_ind_parcellations/CBIG_ArealMSHBM_gMSHBM_generate_individual_parcellation.m, lines 1 to 149 · score 0.76 · diffusion embedding matrices, spatial mask, connectivity profiles, probability, Schaefer400, gradients · Report a mismatch
  3. [3] § Results › Ethnicity/race-related variability in brain functional topography and connectome ↔ stable_projects/brain_parcellation/Lim2026_MSHBM_epilepsy/examples/CBIG_MSHBM_Epilepsy_wrapper.m, the whole file · a weak match · score 0.63 · MS HBM, fMRI, cortical parcellations, rs, locations, network · Report a mismatch
  4. [4] § Results › Ethnicity/race-related variability in brain functional topography and connectome ↔ Code/Split_match/HCP_AA_WA_match_diff.m, lines 1 to 55 · score 0.63 · AA WA, framewise displacement, intracranial volume, HCP, age · Report a mismatch
  5. [5] § Methods › Datasets ↔ external_packages/matlab/non_default_packages/palm/palm-alpha109/fileio/@nifti/private/nifti1.h, lines 1070 to 1158 · score 0.63 · phase encoding directions, duration, scanning, fMRI, dimension · Report a mismatch
  6. [6] § Results › Ethnicity/race-related variability in brain functional topography and connectome ↔ Code/Split_match/HCP_match_WA_with_AAfolds.m, lines 148 to 292 · score 0.60 · Hungarian matching, matched WA, family, AA, split, fold · Report a mismatch
  7. [7] § Results › Ethnicity/race-related variability in brain functional topography and connectome ↔ stable_projects/brain_parcellation/Lim2026_MSHBM_epilepsy/CBIG_MSHBM_Epilepsy_LI.m, the whole file · a weak match · score 0.58 · MS HBM, fMRI, cortical parcellations, network, brain · Report a mismatch
  8. [8] § Results › Lifestyle influences ethnicity/race-related variability in brain functional connectome ↔ Code/KRR_lifestyle_prediction/KRR_confounds_prediction.m, lines 86 to 140 · score 0.56 · social relationships, physical activity, smoking, sleep, Lifestyle, HCP · Report a mismatch
  9. [9] § Methods › Predictive modeling ↔ Code/Split_match/HCP_split_AA_rm_hardtomatch.m, the whole file · a weak match · score 0.55 · model training, cross validated, loop, fold, predict, correlation · Report a mismatch
  10. [10] § Methods › Predictive modeling ↔ Code/Split_match/HCP_match_WA_with_AAfolds.m, lines 148 to 292 · score 0.54 · Hungarian matching, WA, family, AA, split, fold · Report a mismatch
  11. [11] § Methods › Defining individual-specific cortical parcellations and the functional connectome ↔ stable_projects/brain_parcellation/Kong2022_ArealMSHBM/step3_generate_ind_parcellations/CBIG_ArealMSHBM_cMSHBM_generate_individual_parcellation.m, lines 1 to 142 · score 0.54 · spatial mask, connectivity profiles, probability, Schaefer400, parcellations, vertex · Report a mismatch
  12. [12] § Results › Lifestyle influences ethnicity/race-related variability in brain functional connectome ↔ Code/KRR_lifestyle_prediction/KRR_confounds_prediction.m, lines 86 to 140 · score 0.54 · social relationships, physical activity, sleep, KRR, lifestyle, HCP · Report a mismatch
  13. [13] § Methods › Image acquisition and processing ↔ stable_projects/brain_parcellation/Lim2026_MSHBM_epilepsy/examples/CBIG_MSHBM_Epilepsy_wrapper.m, the whole file · a weak match · score 0.53 · motion censoring, fMRI, rs, cortical · Report a mismatch
  14. [14] § Methods › Image acquisition and processing ↔ stable_projects/brain_parcellation/Yan2023_homotopic/code/step1_generate_fmri_input/CBIG_hMRF_build_time_matrix.m, the whole file · a weak match · score 0.52 · cortical vertices, fMRI, censoring, frames, volumes · Report a mismatch

Paper

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The authors' code

MATLAB · 280 lines · 11 KB · no license · 2 matches

  1. function HCP_AA_WA_match_diff(split_AAdir, split_WAdir, full_subj_ls, FD_txt, bhvr_ls_rstr, ...
  2. bhvr_ls_unrstr, num_seeds, mat_out, restricted_csv, unrestricted_csv, match_ls)
  3. % HCP_AA_WA_match_diff(split_AAdir, split_WAdir, full_subj_ls, FD_txt, DV_txt, bhvr_ls_rstr, ...
  4. % bhvr_ls_unrstr, num_seeds, mat_out, restricted_csv, unrestricted_csv, FS_csv)
  5. %
  6. % Compare the demographic & behavioral distributions between selected African Americans and
  7. % white Americans using two-sample t test and K-S test. Usually K-S test was more conservative
  8. % (i.e. bigger p values) than t test, based on the author's experiences in this data. Hence the
  9. % final significance was based on the t test.
  10. %
  11. % Inputs:
  12. % - split_AAdir
  13. % Full path of the directory storing the split folds of African Americans.
  14. % It is the output of `HCP_split_AA_rm_hardtomatch.m`.
  15. % - split_WAdir
  16. % Full path of the directory storing the white Americans that were matched to African Americans.
  17. % It is the output of `HCP_match_WA_with_AAfolds.sh`.
  18. % - full_subj_ls
  19. % Full path of the list of all subject IDs that were used for this project.
  20. % - FD_txt
  21. % Full path of the list of framewise displacement. Each row in this list corresponds to
  22. % the FD of a subject in `full_subj_ls`.
  23. % - DV_txt
  24. % Full path of the list of DVARS. Each row in this list corresponds to the DVARS of a subject
  25. % in `full_subj_ls`.
  26. % - bhvr_ls_rstr
  27. % Full path of a list of behavioral measures that were contained in the HCP restricted CSV.
  28. % Pass 'NONE' if all behavioral measure you want to study were in the unrestricted CSV.
  29. % - bhvr_ls_unrstr
  30. % Full path of a list of behavioral measures that were contained in the HCP unrestricted CSV.
  31. % - num_seeds
  32. % Total number of random splitting repetitions. It needs to be consistent with the maximal
  33. % seed used for `HCP_split_AA_rm_hardtomatch.m`.
  34. % - mat_out
  35. % Full path of output .mat file.
  36. % - restricted_csv (optional)
  37. % Full path of the HCP restricted CSV file. Default (on CSC HPC):
  38. % '/mnt/isilon/CSC1/Yeolab/Data/HCP/S1200/scripts/restricted_hcp_data/...
  39. % RESTRICTED_jingweili_4_12_2017_1200subjects_fill_empty_zygosityGT_by_zygositySR.csv'
  40. % - unrestricted_csv (optional)
  41. % Full path of the HCP unrestricted CSV file. Default (on CSC HPC):
  42. % '/mnt/isilon/CSC1/Yeolab/Data/HCP/S1200/scripts/subject_measures/...
  43. % unrestricted_jingweili_12_7_2017_21_0_16_NEO_A_corrected.csv'
  44. % - FS_csv (optional)
  45. % Full path of the HCP FreeSurfer stats CSV file. This is used to calculate matching
  46. % cost of intracranial volume. Default (on CSC HPC):
  47. % '/mnt/isilon/CSC1/Yeolab/Data/HCP/S1200/scripts/Morphometricity/Anat_Sim_Matrix/...
  48. % FS_jingweili_5_9_2017_2_2_24.csv'
  49. % - match_ls (optional)
  50. % Full path of the list of confounds to be matched. If not passed in, the confounds to
  51. % be checked include age, gender, FD. If 'NONE' is passed in,
  52. % only the difference in behavioral distributions will be checked.
  53. %
  54. % Author: Jingwei Li
  55. %% set default parameters
  56. HCP_dir = '/mnt/isilon/CSC1/Yeolab/Data/HCP/S1200';
  57. if(~exist('restricted_csv', 'var') || isempty(restricted_csv))
  58. restricted_csv = fullfile(HCP_dir, 'scripts', 'restricted_hcp_data', ...
  59. 'RESTRICTED_jingweili_4_12_2017_1200subjects_fill_empty_zygosityGT_by_zygositySR.csv');
  60. end
  61. if(~exist('unrestricted_csv', 'var') || isempty(unrestricted_csv))
  62. unrestricted_csv = fullfile(HCP_dir, 'scripts', 'subject_measures', ...
  63. 'unrestricted_jingweili_12_7_2017_21_0_16_NEO_A_corrected.csv');
  64. end
  65. if(~exist('match_ls', 'var') || isempty(match_ls))
  66. match_var = {'age', 'FD',};
  67. elseif(strcmpi(match_ls, 'none'))
  68. match_var = [];
  69. else
  70. match_var = CBIG_text2cell(match_ls);
  71. end
  72. %% read demographics and behavioral scores
  73. [subjects, ~] = CBIG_text2cell(full_subj_ls);
  74. subjects = subjects';
  75. if(~strcmpi(bhvr_ls_rstr, 'none'))
  76. [bhvr_rstr, n_rstr] = CBIG_text2cell(bhvr_ls_rstr);
  77. else
  78. bhvr_rstr = [];
  79. n_rstr = 0;
  80. end
  81. [bhvr_unrstr, n_unrstr] = CBIG_text2cell(bhvr_ls_unrstr);
  82. behaviors = [bhvr_rstr bhvr_unrstr];
  83. nbehav = n_rstr + n_unrstr;
  84. [~, age_Educ] = CBIG_parse_delimited_txtfile(restricted_csv, {'Race', 'Family_ID'}, ...
  85. {'Age_in_Yrs', 'SSAGA_Educ'}, 'Subject', subjects, ',');
  86. if(~strcmpi(bhvr_ls_rstr, 'none'))
  87. [~, bhvr_rstr_val] = CBIG_parse_delimited_txtfile(restricted_csv, [], ...
  88. bhvr_rstr, 'Subject', subjects, ',');
  89. else
  90. bhvr_rstr_val = [];
  91. end
  92. [sex, ~] = CBIG_parse_delimited_txtfile(unrestricted_csv, {'Gender'}, ...
  93. bhvr_unrstr, 'Subject', subjects, ',');
  94. sex = strcmp(sex, 'M');
  95. bhvr_val = [bhvr_rstr_val sex];
  96. FD = dlmread(FD_txt);
  97. %DV = dlmread(DV_txt);
  98. metric = [];
  99. weigh_idx = [];
  100. for mv = 1:length(match_var)
  101. switch match_var{mv}
  102. case 'age'
  103. metric = [metric age_Educ(:,1)];
  104. % case 'gender'
  105. % metric = [metric sex];
  106. case 'FD'
  107. metric = [metric FD];
  108. otherwise
  109. error('Unknown variable name to be matched')
  110. end
  111. end
  112. metric = [metric bhvr_val];
  113. no_match_idx = weigh_idx;
  114. if(~isempty(match_var))
  115. weigh_idx = [weigh_idx length(match_var)+1];
  116. end
  117. metric = metric - mean(metric,1);
  118. metric = metric ./ sqrt(sum(metric.^2,1));
  119. %% statistical testing for each random seed. Correct for multiple comparisons across all seeds.
  120. H_ks = []; p_ks = []; ksstat = [];
  121. H_tt = []; p_tt = [];
  122. meanA = []; meanW = []; varA = []; varW = [];
  123. outlier_AA = {};
  124. all_mAA = cell(nbehav,1);
  125. all_mWA = cell(nbehav,1);
  126. all_mAA_seed = cell(nbehav,num_seeds);
  127. all_mWA_seed = cell(nbehav,num_seeds);
  128. for seed = 1:num_seeds
  129. load(fullfile(split_AAdir, ['split_AA_5folds_seed' num2str(seed) '.mat']))
  130. load(fullfile(split_WAdir, ['match_WA_seed' num2str(seed) '.mat']))
  131. %%%%%%%%%%%%%%%% for my own debugging purpose
  132. if(~exist('AA_fold', 'var'))
  133. AA_fold = Afr_fold;
  134. end
  135. %%%%%%%%%%%%%%%%%%%%%%%%%%%%%
  136. H_ks_seed = []; p_ks_seed = []; ksstat_seed = [];
  137. H_tt_seed = []; p_tt_seed = [];
  138. meanA_seed = []; meanW_seed = []; varA_seed = []; varW_seed = [];
  139. for b = 1:nbehav
  140. curr_m = metric(:,[1:length(match_var) b+length(match_var)]);
  141. A_metric{b} = [];
  142. W_metric{b} = [];
  143. for f = 1:length(AA_fold.sub_perfold)
  144. [~,Aind] = intersect(subjects, AA_fold.sub_perfold{f});
  145. [~,Wind] = intersect(subjects, best_assign{b}{f});
  146. A_metric{b} = [A_metric{b}; curr_m(Aind, :)];
  147. W_metric{b} = [W_metric{b}; curr_m(Wind, :)];
  148. % the calculation of Hungarian matching cost should be the same as in `HCP_match_WA_with_AAfolds.m`
  149. cost_mat = bsxfun(@minus, reshape(curr_m(Aind,:), [length(Aind) 1 size(curr_m,2)]), ...
  150. reshape(curr_m(Wind,:), [1 size(curr_m(Wind,:))]));
  151. cost_mat(:,:,weigh_idx) = cost_mat(:,:,weigh_idx) .*2;
  152. cost_mat = sum(abs(cost_mat), 3);
  153. [assign, ~] = munkres(cost_mat);
  154. all_mAA{b} = [all_mAA{b}; curr_m(Aind, :)];
  155. all_mWA{b} = [all_mWA{b}; curr_m(Wind(assign), :)];
  156. all_mAA_seed{b,seed} = [all_mAA_seed{b,seed}; curr_m(Aind, :)];
  157. all_mWA_seed{b,seed} = [all_mWA_seed{b,seed}; curr_m(Wind(assign), :)];
  158. % Outlier AAs based on the matching cost
  159. % It helps to decide which AA to be excluded when using `HCP_split_AA_rm_hardtomatch.m` :
  160. % the AA IDs appeared as outliers for multiple behavioral measures can be considered to be ignored.
  161. pair_ind = sub2ind(size(cost_mat), 1:length(Aind), assign);
  162. outlier = isoutlier(cost_mat(pair_ind));
  163. fprintf('Outlier African: %s\n', subjects{Aind(outlier==1)})
  164. outlier_AA = [outlier_AA; subjects(Aind(outlier==1))];
  165. end
  166. curr_H_ks = []; curr_p_ks = []; curr_ksstats = [];
  167. curr_H_tt = []; curr_p_tt = [];
  168. curr_meanA = []; curr_meanW = []; curr_varA = []; curr_varW = [];
  169. for m = 1:size(curr_m,2)
  170. [curr_H_ks(m), curr_p_ks(m), curr_ksstats(m)] = kstest2(A_metric{b}(:,m), W_metric{b}(:,m));
  171. [curr_H_tt(m), curr_p_tt(m)] = ttest2(A_metric{b}(:,m), W_metric{b}(:,m), 'Vartype', 'unequal');
  172. curr_meanA(m) = mean(A_metric{b}(:,m));
  173. curr_meanW(m) = mean(W_metric{b}(:,m));
  174. curr_varA(m) = var(A_metric{b}(:,m));
  175. curr_varW(m) = var(W_metric{b}(:,m));
  176. end
  177. H_ks_seed = [H_ks_seed curr_H_ks];
  178. p_ks_seed = [p_ks_seed curr_p_ks];
  179. ksstat_seed = [ksstat_seed curr_ksstats];
  180. H_tt_seed = [H_tt_seed curr_H_tt];
  181. p_tt_seed = [p_tt_seed curr_p_tt];
  182. meanA_seed = [meanA_seed curr_meanA];
  183. meanW_seed = [meanW_seed curr_meanW];
  184. varA_seed = [varA_seed curr_varA];
  185. varW_seed = [varW_seed curr_varW];
  186. end
  187. H_ks = [H_ks; H_ks_seed];
  188. p_ks = [p_ks; p_ks_seed];
  189. ksstat = [ksstat; ksstat_seed];
  190. H_tt = [H_tt; H_tt_seed];
  191. p_tt = [p_tt; p_tt_seed];
  192. meanA = [meanA; meanA_seed];
  193. meanW = [meanW; meanW_seed];
  194. varA = [varA; varA_seed];
  195. varW = [varW; varW_seed];
  196. end
  197. alpha = 0.05;
  198. H_ks_FDR = FDR(p_ks(:), alpha);
  199. H_tt_FDR = FDR(p_tt(:), alpha);
  200. %% check which (seed, behavior) combinations have significant difference
  201. % in demographic and behavioral distributions between AA and WA
  202. sig_bool = zeros(size(p_tt));
  203. sig_bool(H_tt_FDR) = 1;
  204. matched_mtx = zeros(num_seeds, nbehav);
  205. for b = 1:nbehav
  206. curr_bool = sig_bool(:, ((b-1)*(length(match_var)+1)+1):(b*(length(match_var)+1)) );
  207. if(any(no_match_idx))
  208. curr_bool(:,no_match_idx) = []; % Educ and ICV can't be matched in this data
  209. end
  210. sum_bool = sum(curr_bool, 2);
  211. matched = find(sum_bool == 0);
  212. if(~isempty(matched))
  213. for i = 1:length(matched)
  214. matched_mtx(matched(i),b) = 1;
  215. fprintf('Random seed %d for behavior %s has matched AA & WA in age, FD)\n', ...
  216. matched(i), behaviors{b});
  217. end
  218. end
  219. end
  220. save(mat_out, 'p_ks', 'H_ks', 'H_ks_FDR', 'p_tt', 'H_tt', 'H_tt_FDR', 'matched_mtx', 'outlier_AA')
  221. %% save the statistics into a csv file
  222. header = {'Random split #'};
  223. for b = 1:nbehav
  224. header = [header {[behaviors{b} ': Age'], ...
  225. [behaviors{b} ': FD'], behaviors{b}}];
  226. end
  227. data = [meanA(1,:); varA(1,:)];
  228. data(3+(0:2:(num_seeds-1)*2),:) = meanW;
  229. data(3+(1:2:(num_seeds-1)*2+1),:) = varW;
  230. for row = 1:size(data,1)
  231. for col = 1:size(data,2)
  232. data_rows{col}{row} = num2str(data(row, col));
  233. end
  234. end
  235. data_rows = [cell(1), data_rows];
  236. data_rows{1}{1} = 'All selected African Am (mean)';
  237. data_rows{1}{2} = 'All selected African Am (var)';
  238. for seed = 1:num_seeds
  239. data_rows{1}{3+(seed-1)*2} = sprintf('Seed %d: matched White (mean)', seed);
  240. data_rows{1}{4+(seed-1)*2} = sprintf('Seed %d: matched White (var)', seed);
  241. end
  242. CBIG_write_delimited_txtfile(fullfile(split_WAdir, 'mean_var_AA_vs_WA.csv'), header, data_rows);
  243. end

HCP_AA_WA_match_diff.m at commit e69fd2c, no license · at the source

Overview

Authors: Ziteng Han1, Kexin Wang1, Tiantian Liu1, Fanghui Zhao1, Yunxiao Ma2, Wenrui Li3, Guoyuan Yang1,4, Tianyi Yan1
  1. School of Medical Technology, Beijing Institute of Technology, Beijing, China
  2. School of Life Science, Beijing Institute of Technology, Beijing, China
  3. Department of Biological Sciences, Vanderbilt University, Nashville, TN, USA
  4. School of Interdisciplinary Science, Beijing Institute of Technology, Beijing, China
Institutions: Beijing Institute of Technology (China); Vanderbilt University (United States)
Journal: Research (Washington, D.C.), volume 9, article 1143
Dates: received 13 September 2025; accepted 22 January 2026; published online 24 March 2026
Type: Research article · Language: English
License: CC BY
Identifiers: DOI 10.34133/research.1143 · PMID 41884333 · PMCID PMC13009535 · OpenAlex W7125489114
Open access: gold, a free copy (OpenAlex)
Status: code verified (how the code is found and verified)
Categories: human (organism), cellular / molecular (subfield)
Methods: Connectivity, Statistics, Smoothing, state filtering, decompositions, Machine learning, fMRI & imaging, Preprocessing
Journal subjects: Health Science
Topic: Genetic Associations and Epidemiology (Genetics, Biochemistry, Genetics and Molecular Biology), according to OpenAlex
Citations: not cited yet (Europe PMC); 115 references in the paper

Abstract

Understanding the variation of functional architecture across individuals and populations is fundamental to advancing our knowledge of human health and behavior. Yet, while functional organization differences related to ethnicity/race are consistently reported, their underlying mechanisms remain poorly understood. Here, we apply precision individualized functional mapping to systematically investigate ethnicity/race-related differences between African American (AA) and white American (WA) cohorts in the brain’s intrinsic organization and their associations with lifestyle and transcriptional signatures. We show that variations in network topography and functional connectivity across these ethnic/racial groups follow a hierarchical sensorimotor–association axis and are constrained by brain morphology. Importantly, we identify lifestyle factors—particularly education and substance use—that significantly mediate these associations between ethnicity/race and functional connectivity. Leveraging human brain gene expression data, we further demonstrate that cortical transcriptional patterns are spatially aligned with ethnicity/race-related variability in functional connectivity. Gene ontology analyses of associated genes reveal significant enrichment in biological processes such as synaptic signaling and neuronal system development. Together, these findings uncover a multi-layered framework linking ethnicity/race-related differences in brain function to structural constraints, lifestyle influences, and molecular signatures, and point to the need for a more comprehensive and equitable understanding of human brain diversity.

Reproduced under the paper's license (CC BY), from the paper cited above.

Repositories

Its files are read in the Code ↔ Paper reader above, with 14 matches between paragraphs and lines of code.

thomasyeolab/cbig

License: MIT
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Evidence: files inventoried
Commit: 634f676630929a71297852d01dd92a287103e861, 1 October 2026
Languages: MATLAB (2110), Shell (652), Python (589), C (113), C++ (65), C/C++ (62), R (25), Jupyter (5)
Size: 9,316 files, 3,621 scripts
Software Heritage: not archived
Found in: “Data Availability”
Holds: README, license file, environment (external_packages/python/mapalign-master/requirements.txt, external_packages/python/mapalign-master/setup.py, external_packages/python/yapf-master/setup.cfg, external_packages/python/yapf-master/setup.py), tests, documentation, 2 notebooks
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Tools: NumPy (130 files), PyTorch (122 files), FreeSurfer (94 files), SciPy (61 files), FieldTrip (60 files), Statistics and Machine Learning Toolbox (50 files), FSL (44 files), SPM (40 files), GIfTI library for MATLAB (10 files), Image Processing Toolbox (8 files), Connectome Workbench (8 files), scikit-learn (5 files), AFNI (2 files), Matplotlib (2 files), Tools for NIfTI and ANALYZE image (MATLAB) (2 files), ANTs (1 file), NiBabel (1 file), Nilearn (1 file), tedana (1 file)
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Zenodo 7606653

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12 files

TianyiYanLab/Ethnicity_Race_Diversity

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Commit: e69fd2c62749d0e5dbb2bca99361a37b750216e2, 7 January 2026
Languages: MATLAB (11), R (6), Jupyter (2), Python (1)
Size: 25 files, 20 scripts
Software Heritage: not archived
Found in: “Data Availability”
Holds: README, 2 notebooks
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Tools: lavaan (6 files), Statistics and Machine Learning Toolbox (6 files), NumPy (2 files), pandas (2 files), SciPy (2 files), abagen (1 file), Matplotlib (1 file), PyTorch (1 file), scikit-learn (1 file)
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21 files

pennlinc/spatiotemp_dev_plasticity

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State: the link answers, verified on 30 September 2026
Evidence: files inventoried
Commit: 7f1fa0b151ea2542d58dd1c53004ad2a05e4dd49, 4 February 2023
Languages: R (11)
Size: 19 files, 11 scripts
Software Heritage: not archived
Found in: the Zenodo archive record
Holds: README, 4 notebooks
Not found: license file, CITATION.cff, environment file, tests, continuous integration, documentation
Tools: tidyverse (8 files), ggplot2 (2 files), ggseg (2 files), cowplot (1 file), mgcv (1 file)
Availability: 1 check, the latest on 30 September 2026: the link answers
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12 files

The paper's code and data availability statement is in the Data section.

Tracing map

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Data

Datasets cited

Data Availability

The raw and preprocessed data are available from the HCP (https://www.humanconnectome.org/study/hcp-young-adult/document/1200-subjects-data-release; https://humanconnectome.org/study/hcp-lifespan-development). Human gene expression data are available from the Allen Brain Atlas (https://human.brain-map.org). In our analyses, we also utilized publicly available cortical atlases, including the Schaefer400 atlas (https://github.com/ThomasYeoLab/CBIG/tree/master/stable_projects/brain_parcellation/Schaefer2018_LocalGlobal/Parcellations), the S–A axis (https://github.com/PennLINC/S-A_ArchetypalAxis), and environmental effect maps (https://doi.org/10.5281/zenodo.7606653). The subject lists for both the HCP-YA and HCP-D datasets, along with all predictive feature matrices, are available on our GitHub page (https://github.com/TianyiYanLab/Ethnicity_Race_Diversity). The PLS1 gene lists and Z score weights for both cohorts are provided in Data S1. All data supporting the findings of this study are included in the paper and its Supplementary Materials, and all additional information is available from the authors upon reasonable request. All the codes used to generate the results are available on GitHub (https://github.com/TianyiYanLab/Ethnicity_Race_Diversity).

Reproduced under the paper's license (CC BY), from the paper cited above.

Versions

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Version 1, 30 September 2026: the first record

Recorded: type, language, journal, volume, pages, dates, 8 authors, 1 funder, 107 references.

Cite

This paper

Han, Z., Wang, K., Liu, T., Zhao, F., Ma, Y., Li, W., Yang, G., & Yan, T. (2026). Lifestyle and Transcriptional Signatures Associated with Ethnicity/Race-Related Variations in the Functional Connectome. Research (Washington, D.C.), 9, 1143. https://doi.org/10.34133/research.1143

BibTeX

@article{han2026lifestyle,
author = {Han, Ziteng and Wang, Kexin and Liu, Tiantian and Zhao, Fanghui and Ma, Yunxiao and Li, Wenrui and Yang, Guoyuan and Yan, Tianyi},
title = {{Lifestyle and Transcriptional Signatures Associated with Ethnicity/Race-Related Variations in the Functional Connectome}},
journal = {Research (Washington, D.C.)},
year = {2026},
month = mar,
volume = {9},
pages = {1143},
publisher = {AAAS Science Partner Journal Program},
issn = {2639-5274},
doi = {10.34133/research.1143},
url = {https://doi.org/10.34133/research.1143},
pmid = {41884333},
pmcid = {PMC13009535}
}

RIS

TY - JOUR
AU - Han, Ziteng
AU - Wang, Kexin
AU - Liu, Tiantian
AU - Zhao, Fanghui
AU - Ma, Yunxiao
AU - Li, Wenrui
AU - Yang, Guoyuan
AU - Yan, Tianyi
TI - Lifestyle and Transcriptional Signatures Associated with Ethnicity/Race-Related Variations in the Functional Connectome
T2 - Research (Washington, D.C.)
J2 - Research (Wash D C)
PY - 2026
DA - 2026/03/24
VL - 9
SP - 1143
SN - 2639-5274
PB - AAAS Science Partner Journal Program
DO - 10.34133/research.1143
UR - https://doi.org/10.34133/research.1143
LA - en
ER -

CSL-JSON

{
"id": "10.34133/research.1143",
"type": "article-journal",
"title": "Lifestyle and Transcriptional Signatures Associated with Ethnicity/Race-Related Variations in the Functional Connectome",
"container-title": "Research (Washington, D.C.)",
"author": [
{
"family": "Han",
"given": "Ziteng"
},
{
"family": "Wang",
"given": "Kexin"
},
{
"family": "Liu",
"given": "Tiantian"
},
{
"family": "Zhao",
"given": "Fanghui"
},
{
"family": "Ma",
"given": "Yunxiao"
},
{
"family": "Li",
"given": "Wenrui"
},
{
"family": "Yang",
"given": "Guoyuan"
},
{
"family": "Yan",
"given": "Tianyi"
}
],
"container-title-short": "Research (Wash D C)",
"volume": "9",
"page": "1143",
"DOI": "10.34133/research.1143",
"PMID": "41884333",
"PMCID": "PMC13009535",
"ISSN": "2639-5274",
"publisher": "AAAS Science Partner Journal Program",
"URL": "https://doi.org/10.34133/research.1143",
"language": "en",
"issued": {
"date-parts": [
[
2026,
3,
24
]
]
}
}

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