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Complex harmonic manifolds in mindfulness-based cognitive therapy for major depressive disorder

Overview

  1. Center for Brain and Cognition, Computational Neuroscience Group, Faculty of Medicine and Life Sciences, Universitat Pompeu Fabra, Barcelona, Spain
  2. International Centre for Flourishing, Universities of Oxford (UK), Aarhus (Denmark) and Pompeu Fabra (Spain)
  3. Department of Clinical Medicine, Aarhus University, Aarhus, Denmark
  4. Department of Psychiatry, University of Oxford, Oxford, United Kingdom
  5. Department of Psychiatry and Donders Institute for Brain, Cognition and Behaviour, Radboud University, Nijmegen, the Netherlands
  6. Department of Engineering, University of San Andrés, Buenos Aires, Argentina
  7. Department of Psychiatry, Massachusetts General Hospital/Harvard Medical School, United States
  8. Centre for Eudaimonia and Human Flourishing, Linacre College, University of Oxford, Oxford, United Kingdom
  9. Institució Catalana de la Recerca i Estudis Avançats (ICREA), Barcelona, Spain
  10. Center for Music in the Brain, Department of Clinical Medicine, Aarhus University, Aarhus, Denmark
Dates: published online 8 July 2026
Type: Preprint
License: CC BY-NC-ND
Identifiers: DOI 10.64898/2026.06.26.26356643 · OpenAlex W7167692415
Open access: green, a free copy (OpenAlex)
Status: code on request (how the code is found and verified)
Categories: human (organism), depression (population), clinical / translational (subfield)
Methods: Statistics, Smoothing, state filtering, decompositions, Connectivity, Machine learning
Keywords: Depression, Mindfulness-Based Cognitive Therapy, Complex harmonics, Rumination
Topic: Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes (Experimental and Cognitive Psychology, Psychology), according to OpenAlex
Funding: National Research Foundation (DNRF117); Danmarks Grundforskningsfond (PID2022-136216NB-I00, DNRF 117); ZonMw; Generalitat de Catalunya (2021 SGR 00917, 501100011033, PID2022-136216NB-I00, 2022 FISDU 00229); Radboud Universitair Medisch Centrum; H. Lundbeck A/S; Parkinsonfonden; HORIZON EUROPE Framework Programme; Agència de Gestió d'Ajuts Universitaris i de Recerca (2021SGR00917, 2022 FISDU 00229, 13039/501100011033); European Commission (PID2022-136216NB-I00, 101071900, 13039/501100011033, 501100011033, MICIU/AEI/10); Agencia Estatal de Investigación (501100011033, PID2022-136216NB-I00, 13039, 13039/501100011033, AEI/10)
Citations: not cited yet (Europe PMC); 76 references in the paper

Abstract

The abstract is not reproduced here: the paper's license (CC BY-NC-ND) does not allow it. Read it in the paper, at the publisher or on Europe PMC.

Code

The paper says that its authors' code is available on request: it was not published with the paper, so there is nothing to verify.

Code availability statement

The paper has a code availability statement. Its license (CC BY-NC-ND) does not allow reproducing it here; in short, from what the harvester recognized in it:

  • it says that the code is available on request

Read it in the paper: doi.org/10.64898/2026.06.26.26356643.

Tracing map

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Data

No dataset and no data link were found in the paper.

Data availability statement

The paper has a data availability statement. Its license (CC BY-NC-ND) does not allow reproducing it here; in short, from what the harvester recognized in it:

  • it says that the data are available on request

Read it in the paper: doi.org/10.64898/2026.06.26.26356643.

Versions

The history of this record: each version stored by the harvester or made by a correction of its authors or of the maintainers of its code, and what changed in its facts. The texts of the paper (its abstract, its availability statements) are not part of it; versions that changed only those are not listed.

Version 2, 28 September 2026

  • Authors: added Yonatan Sanz Perl (0000-0002-1270-5564); removed Yonatan Sanz Perl
  • Funding: added National Research Foundation: DNRF117; Danmarks Grundforskningsfond: PID2022-136216NB-I00, DNRF 117; ZonMw; Generalitat de Catalunya: 2021 SGR 00917, 501100011033, PID2022-136216NB-I00, 2022 FISDU 00229; Radboud Universitair Medisch Centrum; H. Lundbeck A/S; Parkinsonfonden; HORIZON EUROPE Framework Programme; Agència de Gestió d'Ajuts Universitaris i de Recerca: 2021SGR00917, 2022 FISDU 00229, 13039/501100011033; European Regional Development Fund: PID2022-136216NB-I00, 101071900, 13039/501100011033, 501100011033, MICIU/AEI/10; Agencia Estatal de Investigación: 501100011033, PID2022-136216NB-I00, 13039, 13039/501100011033, AEI/10

Version 1, 27 September 2026: the first record

Recorded: type, journal, dates, 8 authors, 4 keywords, 71 references.

Cite

This paper

Dagnino, P. C., van der Velden, A. M., Perl, Y. S., Lazar, S. W., Ruhe, H. G., Vohryzek, J., Deco, G., & Kringelbach, M. L. (2026). Complex harmonic manifolds in mindfulness-based cognitive therapy for major depressive disorder. medRxiv (preprint). https://doi.org/10.64898/2026.06.26.26356643

BibTeX

@article{dagnino2026complex,
author = {Dagnino, Paulina Clara and van der Velden, Anne Maj and Perl, Yonatan Sanz and Lazar, Sara W. and Ruhe, Henricus G. and Vohryzek, Jakub and Deco, Gustavo and Kringelbach, Morten L.},
title = {{Complex harmonic manifolds in mindfulness-based cognitive therapy for major depressive disorder}},
journal = {medRxiv (preprint)},
year = {2026},
month = jul,
publisher = {medRxiv},
doi = {10.64898/2026.06.26.26356643},
url = {https://doi.org/10.64898/2026.06.26.26356643}
}

RIS

TY - JOUR
AU - Dagnino, Paulina Clara
AU - van der Velden, Anne Maj
AU - Perl, Yonatan Sanz
AU - Lazar, Sara W.
AU - Ruhe, Henricus G.
AU - Vohryzek, Jakub
AU - Deco, Gustavo
AU - Kringelbach, Morten L.
TI - Complex harmonic manifolds in mindfulness-based cognitive therapy for major depressive disorder
T2 - medRxiv (preprint)
J2 - medRxiv
PY - 2026
DA - 2026/07/08
PB - medRxiv
DO - 10.64898/2026.06.26.26356643
UR - https://doi.org/10.64898/2026.06.26.26356643
ER -

CSL-JSON

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