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A canary in the mind: A single baseline brain scan predicts adolescent depression and anxiety one year later

Overview

Authors: Gustavo Deco1,2,3, Yonatan Sanz Perl1,3,4, Jakub Vohryzek1,3, Elvira Garcia-Guzman1,3, Diego A. Pizzagalli5,6, Ruben Laukkonen3,7,8, Shamil Chandaria3,7,8, Morten L. Kringelbach3,7,8,9
  1. Center for Brain and Cognition, Computational Neuroscience Group, Faculty of Medicine and Life Sciences, Universitat Pompeu Fabra, Barcelona, Spain
  2. Institució Catalana de la Recerca i Estudis Avançats (ICREA), Barcelona, Spain
  3. International Centre for Flourishing, Universities of Oxford (UK), Aarhus (Denmark) and Pompeu Fabra (Spain)
  4. Department of Engineering, Universidad de San Andrés, Buenos Aires, 1644, Argentina
  5. Noel Drury, M.D. Institute for Translational Depression Discoveries, University of California, Irvine, CA, United States
  6. Department of Psychiatry and Human Behavior, Department of Neurobiology and Behavior & Department of Biomedical Engineering, University of California, Irvine, CA, United States
  7. Centre for Eudaimonia and Human Flourishing, Linacre College, University of Oxford, Oxford, UK
  8. Department of Psychiatry, University of Oxford, Oxford, UK
  9. Center for Music in the Brain, Department of Clinical Medicine, Aarhus University, Aarhus, DK
Dates: published online 10 June 2026
Type: Preprint · Language: English
License: CC BY-NC-ND
Identifiers: DOI 10.64898/2026.06.08.26355206 · OpenAlex W7164166464
Open access: green, a free copy (OpenAlex)
Status: data only
Categories: human (organism), other (organism), other condition (population), depression (population), developmental (subfield)
Methods: Spectral & time-frequency, Connectivity, Smoothing, state filtering, decompositions, Machine learning, Statistics, Preprocessing, fMRI & imaging
Topic: Functional Brain Connectivity Studies (Cognitive Neuroscience, Neuroscience), according to OpenAlex
Funding: National Research Foundation (DNRF117); Danmarks Grundforskningsfond (PID2022-136216NB-I00, DNRF 117); HORIZON EUROPE Framework Programme; Agència de Gestió d'Ajuts Universitaris i de Recerca (2021SGR00917, 13039/501100011033); European Commission (PID2022-136216NB-I00, 101071900, 13039/501100011033, 501100011033, MICIU/AEI/10); Agencia Estatal de Investigación (501100011033, PID2022-136216NB-I00, 13039, 13039/501100011033, AEI/10); National Institute of Mental Health (P50MH119467, R37 MH068376, MH119467, MH068376)
Citations: cited by 1 paper (Europe PMC); 67 references in the paper

Abstract

The abstract is not reproduced here: the paper's license (CC BY-NC-ND) does not allow it. Read it in the paper, at the publisher or on Europe PMC.

Code

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Tracing map

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Data

Datasets cited

Versions

The history of this record: each version stored by the harvester or made by a correction of its authors or of the maintainers of its code, and what changed in its facts. The texts of the paper (its abstract, its availability statements) are not part of it; versions that changed only those are not listed.

Version 2, 28 September 2026

  • Language: n/a → en
  • Authors: added Yonatan Sanz Perl (0000-0002-1270-5564); Jakub Vohryzek (0000-0003-0994-5054); Diego A. Pizzagalli (0000-0002-7772-1143); Ruben Laukkonen (0000-0001-8848-9231); removed Yonatan Sanz Perl; Jakub Vohryzek; Diego A. Pizzagalli; Ruben Laukkonen
  • Funding: added National Research Foundation: DNRF117; Danmarks Grundforskningsfond: PID2022-136216NB-I00, DNRF 117; HORIZON EUROPE Framework Programme; Agència de Gestió d'Ajuts Universitaris i de Recerca: 2021SGR00917, 13039/501100011033; European Regional Development Fund: PID2022-136216NB-I00, 101071900, 13039/501100011033, 501100011033, MICIU/AEI/10; Agencia Estatal de Investigación: 501100011033, PID2022-136216NB-I00, 13039, 13039/501100011033, AEI/10; National Institute of Mental Health: P50MH119467, R37 MH068376, MH119467, MH068376

Version 1, 27 September 2026: the first record

Recorded: type, journal, dates, 8 authors, 50 references.

Cite

This paper

Deco, G., Perl, Y. S., Vohryzek, J., Garcia-Guzman, E., Pizzagalli, D. A., Laukkonen, R., Chandaria, S., & Kringelbach, M. L. (2026). A canary in the mind: A single baseline brain scan predicts adolescent depression and anxiety one year later. medRxiv (preprint). https://doi.org/10.64898/2026.06.08.26355206

BibTeX

@article{deco2026canary,
author = {Deco, Gustavo and Perl, Yonatan Sanz and Vohryzek, Jakub and Garcia-Guzman, Elvira and Pizzagalli, Diego A. and Laukkonen, Ruben and Chandaria, Shamil and Kringelbach, Morten L.},
title = {{A canary in the mind: A single baseline brain scan predicts adolescent depression and anxiety one year later}},
journal = {medRxiv (preprint)},
year = {2026},
month = jun,
publisher = {medRxiv},
doi = {10.64898/2026.06.08.26355206},
url = {https://doi.org/10.64898/2026.06.08.26355206}
}

RIS

TY - JOUR
AU - Deco, Gustavo
AU - Perl, Yonatan Sanz
AU - Vohryzek, Jakub
AU - Garcia-Guzman, Elvira
AU - Pizzagalli, Diego A.
AU - Laukkonen, Ruben
AU - Chandaria, Shamil
AU - Kringelbach, Morten L.
TI - A canary in the mind: A single baseline brain scan predicts adolescent depression and anxiety one year later
T2 - medRxiv (preprint)
J2 - medRxiv
PY - 2026
DA - 2026/06/10
PB - medRxiv
DO - 10.64898/2026.06.08.26355206
UR - https://doi.org/10.64898/2026.06.08.26355206
LA - en
ER -

CSL-JSON

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"title": "A canary in the mind: A single baseline brain scan predicts adolescent depression and anxiety one year later",
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"language": "en",
"issued": {
"date-parts": [
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