Effects of single-session transcranial direct current stimulation on response inhibition in stop-signal task performance: A meta-analysis and systematic review.
The 3 matches
- [1] § METHODS › Statistical analysis ↔ Code/analysis_script.R.R, lines 170–255 · score 0.78 · PET PEESE, meta outlier, meta analytic, Sensitivity, fill, funnel
- [2] § RESULTS › Predefined moderators and subgroup analysis in the anodal tDCS model ↔ Code/analysis_script.R.R, lines 128–168 · score 0.62 · electric density, stimulation montage, stop signal, intensity, electrode
- [3] § RESULTS › Characteristics and quality assessment of included studies ↔ Code/analysis_script.R.R, lines 170–255 · score 0.58 · rDLPFC, rIFC, duration, cortex, offline, online
Paper
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The authors' code
R · 257 lines · 8.2 KB · no license · 3 matches
analysis_script.R.R, no license · at the source
Overview
- Research Unit of Diagnosis and Treatment of Mood Cognitive Disorder Chinese Academy of Medical Sciences (No. 2018RU006) Institute of Basic Medical Sciences Chinese Academy of Medical Sciences and Peking Union Medical College Beijing China
- Peking University Sixth Hospital Peking University Institute of Mental Health NHC Key Laboratory of Mental Health (Peking University) National Clinical Research Center for Mental Disorders (Peking University Sixth Hospital) Beijing China
- Department of Psychiatry The Second Affiliated Hospital of Zhejiang University School of Medicine Hangzhou Zhejiang China
- National Institute on Drug Dependence and Beijing Key Laboratory of Drug Dependence Peking University Beijing China
Abstract
Background: Response inhibition is a fundamental component of executive control and a transdiagnostic mechanism underpinning numerous mental disorders. Transcranial direct current stimulation (tDCS) has been investigated as a potential neuromodulatory intervention to enhance response inhibition; however, findings remain inconsistent due to methodological heterogeneity in stimulation parameters and outcome measures.
Aims: To quantitatively evaluate the effects of tDCS on response inhibition as measured by the stop‐signal task (SST) and to explore potential moderators influencing tDCS efficacy.
Methods: This meta‐analysis was conducted in accordance with the Preferred Reporting Items for Systematic Reviews and Meta‐Analyses. We systematically searched PubMed/
Results: The search yielded 2982 articles, of which 35 were considered eligible for inclusion, including 1768 participants. The risk of bias 2 assessment indicated acceptable methodological quality, with the majority of studies rated as low risk of bias or as having some concerns. The overall effect of tDCS on response inhibition was modest yet statistically significant (Hedges' g = −0.22, 95% confidence interval (CI) −0.34 to −0.11, p < 0.001). Subgroup analysis indicated a small‐to‐moderate effect of anodal tDCS (Hedges' g = −0.38, 95% CI −0.51 to −0.26, p < 0.001), especially when targeting the right inferior frontal gyrus, right dorsolateral prefrontal cortex or motor‐related cortex; additionally, online tDCS demonstrated greater efficacy than offline tDCS. Cathodal tDCS demonstrated a small but statistically significant detrimental effect on response inhibition (Hedges' g = 0.19, 95% CI 0.03–0.35, p = 0.023).
Conclusions: Our findings support the potential of anodal tDCS as a neuromodulatory approach for enhancing response inhibition. The polarity‐, target‐ and timing‐specific effects highlight key methodological considerations for optimising tDCS protocols in research on response inhibition impairments.
PROSPERO Registration Number: CRD42024565038.
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analysis_script.R.R — R, 257 lines, 3 matches, not shown here
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Recorded: type, language, journal, volume, issue, pages, dates, 11 authors, 5 keywords, 2 funders, 91 references.
Cite
This paper
Yu, Q., Zhang, M., Zhu, X., Wang, S., Wu, T., Li, Y., Wen, W., Bao, Y., Shi, J., Lu, L., & Deng, J. (2026). Effects of single-session transcranial direct current stimulation on response inhibition in stop-signal task performance: A meta-analysis and systematic review. General psychiatry, 39(4), e70042. https://
BibTeX
@article{yu2026effects,
author = {Yu, Qiuxuan and Zhang, Mingyue and Zhu, Ximei and Wang, Sanwang and Wu, Tingting and Li, Yinjiao and Wen, Wenrong and Bao, Yanping and Shi, Jie and Lu, Lin and Deng, Jiahui},
title = {{Effects of single-session transcranial direct current stimulation on response inhibition in stop-signal task performance: A meta-analysis and systematic review}},
journal = {General psychiatry},
year = {2026},
month = aug,
volume = {39},
number = {4},
pages = {e70042},
publisher = {Shanghai Mental Health Center},
issn = {2517-729X},
doi = {10.1002/
url = {https://
pmid = {42602099},
pmcid = {PMC13473178}
}
RIS
TY - JOUR
AU - Yu, Qiuxuan
AU - Zhang, Mingyue
AU - Zhu, Ximei
AU - Wang, Sanwang
AU - Wu, Tingting
AU - Li, Yinjiao
AU - Wen, Wenrong
AU - Bao, Yanping
AU - Shi, Jie
AU - Lu, Lin
AU - Deng, Jiahui
TI - Effects of single-session transcranial direct current stimulation on response inhibition in stop-signal task performance: A meta-analysis and systematic review
T2 - General psychiatry
J2 - Gen Psychiatr
PY - 2026
DA - 2026/
VL - 39
IS - 4
SP - e70042
SN - 2517-729X
PB - Shanghai Mental Health Center
DO - 10.1002/
UR - https://
LA - en
ER -
CSL-JSON
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