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Revisiting Amplitude of Low-Frequency Fluctuations (ALFF) in Resting-State fMRI: Clarifications and Improvements.

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Paper

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The authors' code

R · 123 lines · 3.5 KB · no license

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It can be read at the source: ALFF_08072025.R.

Overview

Authors: Lejian Huang1,2, Rami Jabakhanji1,2, Andrew D Vigotsky3, Paulo Branco2,4, Marwan N Baliki2,5,6, A Vania Apkarian1,2,4
ORCID iDs: Rami Jabakhanji
  1. Department of Neuroscience, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA
  2. Center for Translational Pain Research, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA
  3. Departments of Biomedical Engineering and Statistics and Data Science, Northwestern University, Evanston, Illinois, USA
  4. Department of Anesthesiology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA
  5. Department of Physical Medicine and Rehabilitation, Northwestern University, Chicago, Illinois, USA
  6. Shirley Ryan AbilityLab, Chicago, Illinois, USA
Institutions: Northwestern University (United States); Shirley Ryan AbilityLab (United States)
Journal: Human brain mapping, volume 47, issue 5, article e70506
Dates: received 11 September 2025; accepted 7 March 2026; published online 23 March 2026; in print April 2026
Type: Other · Language: English
License: CC BY-NC-ND
Identifiers: DOI 10.1002/hbm.70506 · PMID 41867070 · PMCID PMC13081689 · OpenAlex W7140086387
Open access: gold, a free copy (OpenAlex)
Status: code verified
Categories: fMRI (modality), human (organism), methods / tools (subfield)
Methods: Spectral & time-frequency, Smoothing, state filtering, decompositions, Connectivity, fMRI & imaging, Statistics
Keywords: BOLD intensity, fMRI, qmALFF, qmfALFF, spontaneous neural activity, z‐scoring
MeSH: Algorithms*, Brain*, Brain Mapping*, Image Processing, Computer-Assisted*, Magnetic Resonance Imaging*, Datasets as Topic, Humans, Reproducibility of Results, Rest, Software Design (* major topic)
Topic: Functional Brain Connectivity Studies (Cognitive Neuroscience, Neuroscience), according to OpenAlex
Funding: NIH HHS (1P50DA044121-01A1); National Science Foundation (DGE-1324585, DGE‐1324585); National Institutes of Health (1P50DA044121‐01A1)
Citations: not cited yet (Europe PMC); 50 references in the paper

Abstract

The abstract is not reproduced here: the paper's license (CC BY-NC-ND) does not allow it. Read it in the paper, at the publisher or on Europe PMC.

Repository

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lejianhuang/ALFF

License: none: the authors keep all their rights
State: the link answers, verified on 28 September 2026
Evidence: files inventoried
Commit: c208630f71e527399fe58c584124f994dbf47deb, 8 August 2025
Languages: R (1)
Size: 2 files, 1 script
Software Heritage: not archived
Found in: the text, “Procedure for Calculating qmALFF norm and qmfALF”
Not found: README, license file, CITATION.cff, environment file, tests, continuous integration, documentation
Tools: RNifti (1 file)
Availability: 1 check, the latest on 28 September 2026: the link answers
  • 28 September 2026: the link answers
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At the source: github.com/lejianhuang/ALFF

The paper's code and data availability statement is in the Data section.

Tracing map

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Data

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Code and data availability statement

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Read it in the paper: doi.org/10.1002/hbm.70506.

Versions

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Version 1, 28 September 2026: the first record

Recorded: type, language, journal, volume, issue, pages, dates, 6 authors, 6 keywords, 10 MeSH terms, 3 funders, 44 references.

Cite

This paper

Huang, L., Jabakhanji, R., Vigotsky, A. D., Branco, P., Baliki, M. N., & Apkarian, A. V. (2026). Revisiting Amplitude of Low-Frequency Fluctuations (ALFF) in Resting-State fMRI: Clarifications and Improvements. Human brain mapping, 47(5), e70506. https://doi.org/10.1002/hbm.70506

BibTeX

@article{huang2026revisiting,
author = {Huang, Lejian and Jabakhanji, Rami and Vigotsky, Andrew D and Branco, Paulo and Baliki, Marwan N and Apkarian, A Vania},
title = {{Revisiting Amplitude of Low-Frequency Fluctuations (ALFF) in Resting-State fMRI: Clarifications and Improvements}},
journal = {Human brain mapping},
year = {2026},
month = apr,
volume = {47},
number = {5},
pages = {e70506},
publisher = {Wiley},
issn = {1065-9471},
doi = {10.1002/hbm.70506},
url = {https://doi.org/10.1002/hbm.70506},
pmid = {41867070},
pmcid = {PMC13081689}
}

RIS

TY - JOUR
AU - Huang, Lejian
AU - Jabakhanji, Rami
AU - Vigotsky, Andrew D
AU - Branco, Paulo
AU - Baliki, Marwan N
AU - Apkarian, A Vania
TI - Revisiting Amplitude of Low-Frequency Fluctuations (ALFF) in Resting-State fMRI: Clarifications and Improvements
T2 - Human brain mapping
J2 - Hum Brain Mapp
PY - 2026
DA - 2026/04/01
VL - 47
IS - 5
SP - e70506
SN - 1065-9471
PB - Wiley
DO - 10.1002/hbm.70506
UR - https://doi.org/10.1002/hbm.70506
LA - en
ER -

CSL-JSON

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