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Red Blood Cell-Derived Exosomes Deliver Complement C5 to Exacerbate Neuroinflammation and Neuronal Injury after Intracerebral Hemorrhage.

Overview

Authors: Qinglan Chen1, Jun Min1, Xiaomei Lu1, Ziyun Gao2, Yuanyuan Xiong2
  1. Department of Neurology, The Second Affiliated Hospital of Nanchang University,Nanchang, Jiangxi 330006 China
  2. Department of Neurosurgery, The Second Affiliated Hospital of Nanchang University,Nanchang, Jiangxi 330006 China
Institutions: Second Affiliated Hospital of Nanchang University (China)
Journal: Inflammation, volume 49, issue 1, article 108
Dates: received 29 July 2025; accepted 9 January 2026; published online 5 March 2026; in print 2026
Type: Research article · Language: English
License: CC BY-NC-ND
Identifiers: DOI 10.1007/s10753-026-02456-z · PMID 41781600 · PMCID PMC13002700 · OpenAlex W7133506998
Open access: hybrid, a free copy (OpenAlex)
Status: data only
Categories: histology / microscopy (modality), mouse (organism), stroke (population), cellular / molecular (subfield)
Methods: Statistics
Keywords: Intracerebral hemorrhage, Red blood cell-derived exosomes, C5, Macrophages/microglia, M1/M2 polarization
MeSH: Cerebral Hemorrhage*, Erythrocytes*, Exosomes*, Neuroinflammatory Diseases*, Neurons*, Animals, Male, Mice, Mice, Inbred C57BL, Microglia (* major topic)
Topic: Intracerebral and Subarachnoid Hemorrhage Research (Neurology, Medicine), according to OpenAlex
Citations: cited by 1 paper (Europe PMC); 56 references in the paper

Abstract

The abstract is not reproduced here: the paper's license (CC BY-NC-ND) does not allow it. Read it in the paper, at the publisher or on Europe PMC.

Code

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Data

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Data availability statement

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Read it in the paper: doi.org/10.1007/s10753-026-02456-z.

Versions

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Version 1, 30 September 2026: the first record

Recorded: type, language, journal, volume, issue, pages, dates, 5 authors, 5 keywords, 10 MeSH terms, 56 references.

Cite

This paper

Chen, Q., Min, J., Lu, X., Gao, Z., & Xiong, Y. (2026). Red Blood Cell-Derived Exosomes Deliver Complement C5 to Exacerbate Neuroinflammation and Neuronal Injury after Intracerebral Hemorrhage. Inflammation, 49(1), 108. https://doi.org/10.1007/s10753-026-02456-z

BibTeX

@article{chen2026red,
author = {Chen, Qinglan and Min, Jun and Lu, Xiaomei and Gao, Ziyun and Xiong, Yuanyuan},
title = {{Red Blood Cell-Derived Exosomes Deliver Complement C5 to Exacerbate Neuroinflammation and Neuronal Injury after Intracerebral Hemorrhage}},
journal = {Inflammation},
year = {2026},
month = mar,
volume = {49},
number = {1},
pages = {108},
publisher = {Springer Science+Business Media},
issn = {0360-3997},
doi = {10.1007/s10753-026-02456-z},
url = {https://doi.org/10.1007/s10753-026-02456-z},
pmid = {41781600},
pmcid = {PMC13002700}
}

RIS

TY - JOUR
AU - Chen, Qinglan
AU - Min, Jun
AU - Lu, Xiaomei
AU - Gao, Ziyun
AU - Xiong, Yuanyuan
TI - Red Blood Cell-Derived Exosomes Deliver Complement C5 to Exacerbate Neuroinflammation and Neuronal Injury after Intracerebral Hemorrhage
T2 - Inflammation
J2 - Inflammation
PY - 2026
DA - 2026/03/05
VL - 49
IS - 1
SP - 108
SN - 0360-3997
PB - Springer Science+Business Media
DO - 10.1007/s10753-026-02456-z
UR - https://doi.org/10.1007/s10753-026-02456-z
LA - en
ER -

CSL-JSON

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"language": "en",
"issued": {
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