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High Spatial Resolution <sup>23</sup>Na-MRI for Ischemic Brain Injury Detection.

Overview

Authors: Yuanyuan Jiang1, Xiaoqing Alice Zhou1, Takahiko Imai2, Lydia Hawley2, David Hike1, Sohail Mohammed1, Grace Yu1, Cenk Ayata2, David Y. Chung2, Xin Yu1
  1. Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital,Charlestown, MA USA
  2. Department of Neurology, Massachusetts General Hospital, Harvard Medical School,Charlestown, MA USA
Institutions: Massachusetts General Hospital (United States)
Journal: Translational stroke research, volume 17, issue 6, article 117
Dates: received 5 March 2026; accepted 9 October 2026; published online 30 October 2026; in print 2026
Type: Research article · Language: English
License: CC BY-NC-ND
Identifiers: DOI 10.1007/s12975-026-01503-z · PMID 42961728 · PMCID PMC13722787 · OpenAlex W7224740711
Open access: hybrid, a free copy (OpenAlex)
Status: code verified (how the code is found and verified)
Categories: structural MRI / diffusion (modality), mouse (organism), stroke (population)
Methods: Connectivity, Statistics, Smoothing, state filtering, decompositions, fMRI & imaging
Keywords: Sodium MRI, High resolution, Ischemic injury, MCAO, Dual-tuned RF coil
MeSH: Brain*, Brain Injuries*, Brain Ischemia*, Magnetic Resonance Imaging*, Animals, Diffusion Magnetic Resonance Imaging, Disease Models, Animal, Infarction, Middle Cerebral Artery, Male, Mice, Mice, Inbred C57BL, Signal-To-Noise Ratio, Sodium Isotopes (* major topic)
Topic: Advanced MRI Techniques and Applications (Radiology, Nuclear Medicine and Imaging, Medicine), according to OpenAlex
Funding: Andrew David Heitman Foundation; National Institutes of Health (R01NS10296, R25NS065743, KL2TR002542, and K08NS11260, RF1NS113278, RF1NS124778, R01NS122904, R01NS120594, S10 instrument grant (S10 MH124733, S10OD036211)); Ellison Foundation, Andrew David Heitman Foundation; American Heart Association and American Stroke Association (18POST34030369); National Science Foundation (2123971)
Citations: not cited yet (Europe PMC); 73 references in the paper

Abstract

The abstract is not reproduced here: the paper's license (CC BY-NC-ND) does not allow it. Read it in the paper, at the publisher or on Europe PMC.

Code

No file of the authors' code could be read here: it is described below, and read at its source.

tnnc.mgh.harvard.edu/method

License: none: the authors keep all their rights
State: the link answers, verified on 1 November 2026
Evidence: the link answers
Software Heritage: not checked
Found in: the text, “1 H-MRI and 23 Na-MRI Acquisiton”
Not found: README, license file, CITATION.cff, environment file, tests, continuous integration, documentation
Availability: 1 check, the latest on 1 November 2026: the link answers (HTTP 200)
  • 1 November 2026: the link answers (HTTP 200)

Tracing map

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  • 0 scripts, each with its path and the digest of its content;
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Its JSON (tracing-map.json) is deposited on Zenodo with its DOI once the map is validated.

Data

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Data availability statement

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Read it in the paper: doi.org/10.1007/s12975-026-01503-z.

Versions

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Version 1, 1 November 2026: the first record

Recorded: type, language, journal, volume, issue, pages, dates, 10 authors, 5 keywords, 13 MeSH terms, 5 funders, 72 references.

Cite

This paper

Jiang, Y., Zhou, X. A., Imai, T., Hawley, L., Hike, D., Mohammed, S., Yu, G., Ayata, C., Chung, D. Y., & Yu, X. (2026). High Spatial Resolution <sup>23</sup>Na-MRI for Ischemic Brain Injury Detection. Translational stroke research, 17(6), 117. https://doi.org/10.1007/s12975-026-01503-z

BibTeX

@article{jiang2026high,
author = {Jiang, Yuanyuan and Zhou, Xiaoqing Alice and Imai, Takahiko and Hawley, Lydia and Hike, David and Mohammed, Sohail and Yu, Grace and Ayata, Cenk and Chung, David Y. and Yu, Xin},
title = {{High Spatial Resolution <sup>23</sup>Na-MRI for Ischemic Brain Injury Detection}},
journal = {Translational stroke research},
year = {2026},
month = oct,
volume = {17},
number = {6},
pages = {117},
publisher = {Springer Science+Business Media},
issn = {1868-4483},
doi = {10.1007/s12975-026-01503-z},
url = {https://doi.org/10.1007/s12975-026-01503-z},
pmid = {42961728},
pmcid = {PMC13722787}
}

RIS

TY - JOUR
AU - Jiang, Yuanyuan
AU - Zhou, Xiaoqing Alice
AU - Imai, Takahiko
AU - Hawley, Lydia
AU - Hike, David
AU - Mohammed, Sohail
AU - Yu, Grace
AU - Ayata, Cenk
AU - Chung, David Y.
AU - Yu, Xin
TI - High Spatial Resolution <sup>23</sup>Na-MRI for Ischemic Brain Injury Detection
T2 - Translational stroke research
J2 - Transl Stroke Res
PY - 2026
DA - 2026/10/30
VL - 17
IS - 6
SP - 117
SN - 1868-4483
PB - Springer Science+Business Media
DO - 10.1007/s12975-026-01503-z
UR - https://doi.org/10.1007/s12975-026-01503-z
LA - en
ER -

CSL-JSON

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"author": [
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"container-title-short": "Transl Stroke Res",
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