OSCR

Early-Life Cumulative Intake of Ultra-Processed Foods and Subcortical Brain Volume at Age Six Years: A Prospective Cohort Study.

Overview

Authors: Jonatan Ottino-González1, Shana Adise1,2, Alexandra Descarpentrie1, Sevan Esaian1, Katherine M Marquess3, Devendra Paudel3, Haonan Li3, Tanya L Alderete3, Ravi Bansal4,5, Bradley S Peterson4,5, Michael I Goran1
ORCID iDs: Jonatan Ottino-González, Shana Adise, Alexandra Descarpentrie, Sevan Esaian, Katherine M Marquess, Devendra Paudel, Haonan Li, Tanya L Alderete, Ravi Bansal, Bradley S Peterson, Michael I Goran
  1. Department of Pediatrics, Division of Endocrinology, Diabetes and Metabolism, Children’s Hospital Los Angeles
  2. Department of Nutritional Sciences, University of Georgia
  3. Department of Environmental Health and Engineering, Bloomberg School of Public Health
  4. Department of Pediatrics, Division of Child and Adolescent Psychiatry, Children’s Hospital Los Angeles
  5. Department of Psychiatry and Behavioral Sciences, Keck School of Medicine at the University of Southern California
Institutions: Children's Hospital of Los Angeles (United States); University of Georgia (United States); University of Southern California (United States)
Journal: The American journal of clinical nutrition, volume 124, issue 2, article 101350
Dates: received 9 February 2026; accepted 11 May 2026; published online 2 June 2026; in print August 2026
Type: Research article · Language: English
License: CC BY-NC-ND
Identifiers: DOI 10.1016/j.ajcnut.2026.101350 · PMID 42373346 · PMCID PMC13446154 · OpenAlex W7163141043
Open access: hybrid, a free copy (OpenAlex)
Status: code on request
Categories: structural MRI / diffusion (modality), human (organism), developmental (subfield)
Methods: Statistics, Preprocessing, Physiology & signal measures
Keywords: Neurodevelopment, Brain, Cognition, Nutrition, Ultra-processed foods, Cohort, Infancy, Childhood, Early-life
MeSH: Brain*, Diet*, Fast Foods*, Birth Cohort, Child, Child Development, Child, Preschool, Cognition, Energy Intake, Female, Humans, Infant, Magnetic Resonance Imaging, Male, Prospective Studies (* major topic)
Topic: Consumer Attitudes and Food Labeling (Public Health, Environmental and Occupational Health, Medicine), according to OpenAlex
Funding: National Institute on Minority Health and Health Disparities (P50MD017344, RCDF-2024-000016305); National Institute of Diabetes and Digestive and Kidney Diseases Division of Diabetes Endocrinology and Metabolic Diseases (R01DK109161, R01DK110793, K01DK135847, R01DK059211); National Institute of Diabetes and Digestive and Kidney Diseases; Children's Hospital Los Angeles The Saban Research Institute (RCDF-2024-000016305); NIEHS NIH HHS (T32 ES007141); National Institute of Environmental Health Sciences (2T32ES007141); NIMHD NIH HHS (P50 MD017344); NIDDK NIH HHS (R01 DK110793)
Citations: not cited yet (Europe PMC); 53 references in the paper

Abstract

The abstract is not reproduced here: the paper's license (CC BY-NC-ND) does not allow it. Read it in the paper, at the publisher or on Europe PMC.

Code

The paper says that its authors' code is available on request: it was not published with the paper, so there is nothing to verify.

The paper's code and data availability statement is in the Data section.

Tracing map

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Data

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Code and data availability statement

The paper has a code and data availability statement. Its license (CC BY-NC-ND) does not allow reproducing it here; in short, from what the harvester recognized in it:

  • it says that the data are available on request
  • it says that the code is available on request

Read it in the paper: doi.org/10.1016/j.ajcnut.2026.101350.

Versions

The history of this record: each version stored by the harvester or made by a correction of its authors or of the maintainers of its code, and what changed in its facts. The texts of the paper (its abstract, its availability statements) are not part of it; versions that changed only those are not listed.

Version 2, 28 September 2026

  • Authors: added Sevan Esaian (0009-0006-6473-3168); Michael I Goran (0000-0002-6897-6961); removed Sevan Esaian; Michael I Goran

Version 1, 27 September 2026: the first record

Recorded: type, language, journal, volume, issue, pages, dates, 11 authors, 9 keywords, 15 MeSH terms, 8 funders, 50 references.

Cite

This paper

Ottino-González, J., Adise, S., Descarpentrie, A., Esaian, S., Marquess, K. M., Paudel, D., Li, H., Alderete, T. L., Bansal, R., Peterson, B. S., & Goran, M. I. (2026). Early-Life Cumulative Intake of Ultra-Processed Foods and Subcortical Brain Volume at Age Six Years: A Prospective Cohort Study. The American journal of clinical nutrition, 124(2), 101350. https://doi.org/10.1016/j.ajcnut.2026.101350

BibTeX

@article{ottinogonzalez2026early,
author = {Ottino-González, Jonatan and Adise, Shana and Descarpentrie, Alexandra and Esaian, Sevan and Marquess, Katherine M and Paudel, Devendra and Li, Haonan and Alderete, Tanya L and Bansal, Ravi and Peterson, Bradley S and Goran, Michael I},
title = {{Early-Life Cumulative Intake of Ultra-Processed Foods and Subcortical Brain Volume at Age Six Years: A Prospective Cohort Study}},
journal = {The American journal of clinical nutrition},
year = {2026},
month = jun,
volume = {124},
number = {2},
pages = {101350},
publisher = {American Society for Nutrition},
issn = {0002-9165},
doi = {10.1016/j.ajcnut.2026.101350},
url = {https://doi.org/10.1016/j.ajcnut.2026.101350},
pmid = {42373346},
pmcid = {PMC13446154}
}

RIS

TY - JOUR
AU - Ottino-González, Jonatan
AU - Adise, Shana
AU - Descarpentrie, Alexandra
AU - Esaian, Sevan
AU - Marquess, Katherine M
AU - Paudel, Devendra
AU - Li, Haonan
AU - Alderete, Tanya L
AU - Bansal, Ravi
AU - Peterson, Bradley S
AU - Goran, Michael I
TI - Early-Life Cumulative Intake of Ultra-Processed Foods and Subcortical Brain Volume at Age Six Years: A Prospective Cohort Study
T2 - The American journal of clinical nutrition
J2 - Am J Clin Nutr
PY - 2026
DA - 2026/06/02
VL - 124
IS - 2
SP - 101350
SN - 0002-9165
PB - American Society for Nutrition
DO - 10.1016/j.ajcnut.2026.101350
UR - https://doi.org/10.1016/j.ajcnut.2026.101350
LA - en
ER -

CSL-JSON

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