OSCR

The atypical adhesion GPCR ADGRA1 controls hippocampal inhibitory circuit function.

Overview

Authors: Baris Tosun1, Kelly Honkanen1, Elizabeth Orput1, Swarada Kulkarni1, Duy Lan Huong Bui1, Richard C. Sando1,2
  1. Department of Pharmacology, Vanderbilt Brain Institute, Vanderbilt University, Nashville, TN 37240, USA
  2. Lead contact
Institutions: Vanderbilt University (United States)
Journal: Cell reports, volume 45, issue 4, article 117255
Dates: published online 9 April 2026; in print April 2026
Type: Research article · Language: English
License: CC BY-NC-ND
Identifiers: DOI 10.1016/j.celrep.2026.117255 · PMID 41961591 · PMCID PMC13178472 · OpenAlex W4412779261
Open access: gold, a free copy (OpenAlex)
Status: code on request
Categories: cellular / molecular (subfield)
Methods: Statistics, Evoked potentials, fMRI & imaging, Smoothing, state filtering, decompositions
Keywords: Synapse, Inhibitory Synapse, Orphan Gpcr, Adhesion Gpcr, Cp: Neuroscience, Fast-spiking Pv Neuron
Topic: Receptor Mechanisms and Signaling (Molecular Biology, Biochemistry, Genetics and Molecular Biology), according to OpenAlex
Funding: NIH (R00-MH117235, DP2MH140134); Vanderbilt University; NIMH NIH HHS (R00 MH117235, DP2 MH140134); Alfred P. Sloan Foundation
Citations: cited by 1 paper (Europe PMC); 37 references in the paper
Research resources: Anti-GFAP chicken RRID:AB_1074620, Anti-HA rabbit RRID:AB_1549585, Anti-Bassoon mouse RRID:AB_1860018, Anti-MAP2 chicken RRID:AB_2138173, Anti-GAD67 mouse RRID:AB_2278725, Anti-NeuN mouse RRID:AB_2298772, Goat anti-mouse Alexa Fluor 488 RRID:AB_2534069, Goat anti-mouse Alexa Fluor 546 RRID:AB_2534071, Goat anti-rabbit Alexa Fluor 546 RRID:AB_2534077, Goat anti-mouse Alexa Fluor 647 RRID:AB_2535805, Goat anti-rabbit Alexa Fluor 647 RRID:AB_2535813, Goat anti-guinea pig Alexa Fluor 555 RRID:AB_2535856, Goat anti-chicken Alexa Fluor 647 RRID:AB_2535866, Goat anti-guinea pig Alexa Fluor 647 RRID:AB_2535867, Anti-HA mouse RRID:AB_2565335, Goat anti-rabbit Alexa Fluor 488 RRID:AB_2576217, Anti-Gephyrin mouse RRID:AB_2619837, Anti-SHANK2 guinea pig RRID:AB_2619861, Anti-AnkG rabbit RRID:AB_2661876, Anti-Synaptotagmin-2 guinea pig RRID:AB_2744654, Anti-GNA13 mouse RRID:AB_2882483, Anti-βactin mouse RRID:AB_476692, Anti-Homer1 rabbit RRID:AB_887730, Anti-Syn1/2 rabbit RRID:AB_887804, Anti-Synaptoporin rabbit RRID:AB_887841, Anti-Vgat guinea pig RRID:AB_887873

Abstract

The abstract is not reproduced here: the paper's license (CC BY-NC-ND) does not allow it. Read it in the paper, at the publisher or on Europe PMC.

Code

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The paper's code and data availability statement is in the Data section.

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Data

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Code and data availability statement

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  • it says that the code is available on request

Read it in the paper: doi.org/10.1016/j.celrep.2026.117255.

Versions

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Version 1, 29 September 2026: the first record

Recorded: type, language, journal, volume, issue, pages, dates, 6 authors, 6 keywords, 4 funders, 37 references, 26 RRIDs.

Cite

This paper

Tosun, B., Honkanen, K., Orput, E., Kulkarni, S., Bui, D. L. H., & Sando, R. C. (2026). The atypical adhesion GPCR ADGRA1 controls hippocampal inhibitory circuit function. Cell reports, 45(4), 117255. https://doi.org/10.1016/j.celrep.2026.117255

BibTeX

@article{tosun2026atypical,
author = {Tosun, Baris and Honkanen, Kelly and Orput, Elizabeth and Kulkarni, Swarada and Bui, Duy Lan Huong and Sando, Richard C.},
title = {{The atypical adhesion GPCR ADGRA1 controls hippocampal inhibitory circuit function}},
journal = {Cell reports},
year = {2026},
month = apr,
volume = {45},
number = {4},
pages = {117255},
publisher = {Cell Press},
issn = {2211-1247},
doi = {10.1016/j.celrep.2026.117255},
url = {https://doi.org/10.1016/j.celrep.2026.117255},
pmid = {41961591},
pmcid = {PMC13178472}
}

RIS

TY - JOUR
AU - Tosun, Baris
AU - Honkanen, Kelly
AU - Orput, Elizabeth
AU - Kulkarni, Swarada
AU - Bui, Duy Lan Huong
AU - Sando, Richard C.
TI - The atypical adhesion GPCR ADGRA1 controls hippocampal inhibitory circuit function
T2 - Cell reports
J2 - Cell Rep
PY - 2026
DA - 2026/04/09
VL - 45
IS - 4
SP - 117255
SN - 2211-1247
PB - Cell Press
DO - 10.1016/j.celrep.2026.117255
UR - https://doi.org/10.1016/j.celrep.2026.117255
LA - en
ER -

CSL-JSON

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"PMCID": "PMC13178472",
"ISSN": "2211-1247",
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"language": "en",
"issued": {
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