Comparative evaluation of oncolytic viruses reveals opposing preferences for glioblastoma subtypes.

Overview

Authors: Tine Deconinck¹, Tim Dierckx¹, Frederik De Smet², Jim Baggen¹, Dirk Daelemans¹

ORCID iDs: Tine Deconinck, Dirk Daelemans

KU Leuven Department of Microbiology, Immunology and Transplantation, Molecular Genetics and Therapeutics in Virology and Oncology Research Group, Rega Institute, Leuven Cancer Institute, 3000 Leuven, Belgium
KU Leuven Department of Imaging and Pathology, Laboratory for Precision Cancer Medicine, Translational Cell and Tissue Research, Leuven Cancer Institute, 3000 Leuven, Belgium

Institutions: Rega Institute for Medical Research (Belgium); KU Leuven (Belgium)

Journal: Molecular therapy. Oncology, volume 34, issue 3, article 201263

Dates: received 13 November 2025; accepted 9 June 2026; published online 11 June 2026

Type: Research article · Language: English

License: CC BY-NC-ND

Identifiers: DOI 10.1016/j.omton.2026.201263 · PMID 42441280 · PMCID PMC13334811 · OpenAlex W7164345028

Open access: gold, a free copy (OpenAlex)

Status: code on request

Categories: human (organism), other condition (population)

Methods: Statistics, Smoothing, state filtering, decompositions, Machine learning, Evoked potentials, Connectivity

Keywords: oncolytic virotherapy, glioblastoma, brain tumor, CNS tumor, personalized medicine

Topic: Virus-based gene therapy research (Genetics, Biochemistry, Genetics and Molecular Biology), according to OpenAlex

Funding: KU Leuven Research Council (3M240253); Research Foundation Flanders (11M2425N); KU Leuven

Citations: cited by 1 paper (Europe PMC); 84 references in the paper

Research resources: RRID:CVCL_0023, RRID:CVCL_0030, ATCC VR-356) in HeLa Chang liver cells RRID:CVCL_0238, RRID:CVCL_0574, RRID:CVCL_1915, RRID:CVCL_2480, RRID:CVCL_3009, Samtools 1.5 RRID:SCR_002105, RRID:SCR_002798, RRID:SCR_004463, RRID:SCR_006813, RRID:SCR_010974, Adapters were trimmed with cutadapt 1.15 RRID:SCR_011841, FeatureCounts 1.5.3 RRID:SCR_012919, RRID:SCR_014601, RRID:SCR_016341, Using bowtie 2.3.3.1 RRID:SCR_016368, RRID:SCR_016863, CellRanger RRID:SCR_017344, using fgsea82 1.20.0 RRID:SCR_020938

Abstract

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Read it in the paper: doi.org/10.1016/j.omton.2026.201263.

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Version 1, 27 September 2026: the first record

Recorded: type, language, journal, volume, issue, pages, dates, 5 authors, 5 keywords, 3 funders, 81 references, 20 RRIDs.

Cite

This paper

Deconinck, T., Dierckx, T., De Smet, F., Baggen, J., & Daelemans, D. (2026). Comparative evaluation of oncolytic viruses reveals opposing preferences for glioblastoma subtypes. Molecular therapy. Oncology, 34(3), 201263. https://doi.org/10.1016/j.omton.2026.201263

BibTeX

@article{deconinck2026comparative, author = {Deconinck, Tine and Dierckx, Tim and De Smet, Frederik and Baggen, Jim and Daelemans, Dirk}, title = {{Comparative evaluation of oncolytic viruses reveals opposing preferences for glioblastoma subtypes}}, journal = {Molecular therapy. Oncology}, year = {2026}, month = jun, volume = {34}, number = {3}, pages = {201263}, publisher = {American Society of Gene \& Cell Therapy}, issn = {2950-3299}, doi = {10.1016/j.omton.2026.201263}, url = {https://doi.org/10.1016/j.omton.2026.201263}, pmid = {42441280}, pmcid = {PMC13334811} }

RIS

TY - JOUR AU - Deconinck, Tine AU - Dierckx, Tim AU - De Smet, Frederik AU - Baggen, Jim AU - Daelemans, Dirk TI - Comparative evaluation of oncolytic viruses reveals opposing preferences for glioblastoma subtypes T2 - Molecular therapy. Oncology J2 - Mol Ther Oncol PY - 2026 DA - 2026/06/11 VL - 34 IS - 3 SP - 201263 SN - 2950-3299 PB - American Society of Gene & Cell Therapy DO - 10.1016/j.omton.2026.201263 UR - https://doi.org/10.1016/j.omton.2026.201263 LA - en ER -

CSL-JSON

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