Trisomy 21 Drives ADARB1 Overexpression and Premature RNA Recoding in the Developing Fetal Brain.
Overview
14 affiliations
- Seaver Autism Center for Research and Treatment, Icahn School of Medicine at Mount Sinai,New York, NY USA
- MINDICH Child Health and Development Institute, Icahn School of Medicine at Mount Sinai,New York, NY USA
- Department of Psychiatry, Icahn School of Medicine at Mount Sinai,New York, NY USA
- Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai,New York, NY USA
- The Lieber Institute for Brain Development,Baltimore, MD USA
- Department of Psychiatric and Behavioral Sciences, Johns Hopkins School of Medicine,Baltimore, MD USA
- Department of Neurology, Johns Hopkins School of Medicine,Baltimore, MD USA
- Department of Neuroscience, Johns Hopkins School of Medicine,Baltimore, MD USA
- Department of Genetic Medicine, Johns Hopkins University School of Medicine,Baltimore, MD USA
- Molecular Medicine Center, Department of Medical Chemistry and Biochemistry, Medical Faculty, Medical University of Sofia,Sofia, Bulgaria
- Department of Obstetrics and Gynecology, Medical University of Sofia,Sofia, Bulgaria
- Neonatology Clinic, University Hospital of Obstetrics and Gynecology “Maichin Dom”,Sofia, Bulgaria
- Department of Psychiatry, The University of Arizona,Tucson, AZ USA
- Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University,Richmond, VA USA
Abstract
The abstract is not reproduced here: the paper's license (CC BY-NC-ND) does not allow it. Read it in the paper, at the publisher or on Europe PMC.
Code
No file of the authors' code could be read here: it is described below, and read at its source.
BreenMS/Trisomy
Availability: 1 check, the latest on 30 September 2026: the link is dead
- 30 September 2026: the link is dead
Code availability statement
The paper has a code availability statement. Its license (CC BY-NC-ND) does not allow reproducing it here; in short, from what the harvester recognized in it:
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Trisomy
Read it in the paper: doi.org/10.1038/s41467-026-70217-5.
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Data
Datasets cited
- geo:GSE301886, at NCBI GEO; found in “Data availability”
Code and data availability statement
The paper has a code and data availability statement. Its license (CC BY-NC-ND) does not allow reproducing it here; in short, from what the harvester recognized in it:
- it points to a dataset: NCBI GEO GSE301886
- it points to the authors' code: BreenMS/
Trisomy
Read it in the paper: doi.org/10.1038/s41467-026-70217-5.
Versions
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Version 1, 30 September 2026: the first record
Recorded: type, language, journal, volume, issue, pages, dates, 15 authors, 4 keywords, 17 MeSH terms, 1 funder, 67 references.
Cite
This paper
Breen, M. S., Yang, A., Wang, X., Rodriguez de los Santos, M., Tao, R., Weinberger, D. R., Kleinman, J. E., Mihova, K., Stancheva, G., Savova, S., Kaneva, R., Dimitrova, V., Vladimirov, V., Hyde, T. M., & Buxbaum, J. D. (2026). Trisomy 21 Drives ADARB1 Overexpression and Premature RNA Recoding in the Developing Fetal Brain. Nature communications, 17(1), 2797. https://
BibTeX
@article{breen2026trisom
author = {Breen, Michael S. and Yang, Andy and Wang, Xuran and Rodriguez de los Santos, Miguel and Tao, Ran and Weinberger, Daniel R. and Kleinman, Joel E. and Mihova, Kalina and Stancheva, Gergana and Savova, Sylvia and Kaneva, Radka and Dimitrova, Violeta and Vladimirov, Vladimir and Hyde, Thomas M. and Buxbaum, Joseph D.},
title = {{Trisomy 21 Drives ADARB1 Overexpression and Premature RNA Recoding in the Developing Fetal Brain}},
journal = {Nature communications},
year = {2026},
month = mar,
volume = {17},
number = {1},
pages = {2797},
publisher = {Nature Publishing Group},
issn = {2041-1723},
doi = {10.1038/
url = {https://
pmid = {41917044},
pmcid = {PMC13039865}
}
RIS
TY - JOUR
AU - Breen, Michael S.
AU - Yang, Andy
AU - Wang, Xuran
AU - Rodriguez de los Santos, Miguel
AU - Tao, Ran
AU - Weinberger, Daniel R.
AU - Kleinman, Joel E.
AU - Mihova, Kalina
AU - Stancheva, Gergana
AU - Savova, Sylvia
AU - Kaneva, Radka
AU - Dimitrova, Violeta
AU - Vladimirov, Vladimir
AU - Hyde, Thomas M.
AU - Buxbaum, Joseph D.
TI - Trisomy 21 Drives ADARB1 Overexpression and Premature RNA Recoding in the Developing Fetal Brain
T2 - Nature communications
J2 - Nat Commun
PY - 2026
DA - 2026/
VL - 17
IS - 1
SP - 2797
SN - 2041-1723
PB - Nature Publishing Group
DO - 10.1038/
UR - https://
LA - en
ER -
CSL-JSON
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