OSCR

Catecholaminergic neurons boost fibroblast osteogenic activity in keloid.

Overview

Authors: Fangzhou LOU1,2, Jihuan LIANG1,2, Yang SUN1,2, Fengjiao ZHANG1,2, Xiaojie CAI1,2, Siyu Deng1,2, Zhenyao Xu1,2, Qili PENG3, Aie Xu4, Rui CHEN3, Honglin WANG1,2
ORCID iDs: Xiaojie CAI, Qili PENG, Rui CHEN, Honglin WANG
  1. Precision Research Center for Refractory Diseases, Shanghai Jiao Tong University Pioneer Research Institute for Molecular and Cell Therapies, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine,Shanghai, China
  2. State Key Laboratory of Innovative Immunotherapy, School of Pharmaceutical Sciences, Shanghai Jiao Tong University,Shanghai, China
  3. Department of Plastic Surgery, Renji Hospital, Shanghai Jiao Tong University School of Medicine,Shanghai, China
  4. Department of Dermatology, Hangzhou Third People’s Hospital,Hangzhou, China
Institutions: Shanghai First People's Hospital (China); Shanghai Jiao Tong University (China); Department of Dermatology, Hangzhou Third People’s Hospital,Hangzhou, China
Journal: Nature communications, volume 17, issue 1, article 6286
Dates: received 21 October 2024; accepted 18 April 2026; published online 9 May 2026
Type: Research article · Language: English
License: CC BY-NC-ND
Identifiers: DOI 10.1038/s41467-026-72823-9 · PMID 42106323 · PMCID PMC13376770 · OpenAlex W7160709970
Open access: gold, a free copy (OpenAlex)
Status: data only
Categories: human (organism), rat (organism), cellular / molecular (subfield)
Methods: Statistics, Smoothing, state filtering, decompositions, fMRI & imaging
Keywords: Skin diseases, Mechanisms of disease, Cell signalling
MeSH: Keloid*, Stromal Cells*, Adrenergic beta-1 Receptor Antagonists, Adult, Animals, Catecholamines, Core Binding Factor Alpha 1 Subunit, Disease Models, Animal, DNA-Binding Proteins, Extracellular Matrix, Fibroblasts, Humans, Integrin-Binding Sialoprotein, Neurons, Osteogenesis, Protein Biosynthesis, Rats, Receptors, Adrenergic, beta-1, Single-Cell Gene Expression Analysis (* major topic)
Topic: Dermatologic Treatments and Research (Dermatology, Medicine), according to OpenAlex
Funding: National Natural Science Foundation of China (National Science Foundation of China) (82450903); Shanghai Science and Technology Committee (2024XJQ02); Natural Science Foundation of Shanghai Municipality (23ZR1480700)
Citations: not cited yet (Europe PMC); 56 references in the paper

Abstract

The abstract is not reproduced here: the paper's license (CC BY-NC-ND) does not allow it. Read it in the paper, at the publisher or on Europe PMC.

Code

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Data

Datasets cited

Data availability statement

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  • no repository, dataset or request procedure was recognized in it

Read it in the paper: doi.org/10.1038/s41467-026-72823-9.

Versions

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Version 1, 28 September 2026: the first record

Recorded: type, language, journal, volume, issue, pages, dates, 11 authors, 3 keywords, 19 MeSH terms, 3 funders, 56 references.

Cite

This paper

LOU, F., LIANG, J., SUN, Y., ZHANG, F., CAI, X., Deng, S., Xu, Z., PENG, Q., Xu, A., CHEN, R., & WANG, H. (2026). Catecholaminergic neurons boost fibroblast osteogenic activity in keloid. Nature communications, 17(1), 6286. https://doi.org/10.1038/s41467-026-72823-9

BibTeX

@article{lou2026catecholaminergic,
author = {LOU, Fangzhou and LIANG, Jihuan and SUN, Yang and ZHANG, Fengjiao and CAI, Xiaojie and Deng, Siyu and Xu, Zhenyao and PENG, Qili and Xu, Aie and CHEN, Rui and WANG, Honglin},
title = {{Catecholaminergic neurons boost fibroblast osteogenic activity in keloid}},
journal = {Nature communications},
year = {2026},
month = may,
volume = {17},
number = {1},
pages = {6286},
publisher = {Nature Publishing Group},
issn = {2041-1723},
doi = {10.1038/s41467-026-72823-9},
url = {https://doi.org/10.1038/s41467-026-72823-9},
pmid = {42106323},
pmcid = {PMC13376770}
}

RIS

TY - JOUR
AU - LOU, Fangzhou
AU - LIANG, Jihuan
AU - SUN, Yang
AU - ZHANG, Fengjiao
AU - CAI, Xiaojie
AU - Deng, Siyu
AU - Xu, Zhenyao
AU - PENG, Qili
AU - Xu, Aie
AU - CHEN, Rui
AU - WANG, Honglin
TI - Catecholaminergic neurons boost fibroblast osteogenic activity in keloid
T2 - Nature communications
J2 - Nat Commun
PY - 2026
DA - 2026/05/09
VL - 17
IS - 1
SP - 6286
SN - 2041-1723
PB - Nature Publishing Group
DO - 10.1038/s41467-026-72823-9
UR - https://doi.org/10.1038/s41467-026-72823-9
LA - en
ER -

CSL-JSON

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