OSCR

Chromosome-level genome assembly and annotation of the moon jellyfish Aurelia coerulea.

Overview

Authors: Xinyue Hu1,2,3, Yang Guo4, Ze Zhang2,3,5, Liyuan Wang4, Duoyuan Chen2,3, Zhenkun Zhuang2,3, Minxiao Wang4, Shiping Liu2,3, Song Feng4
ORCID iDs: Yang Guo, Ze Zhang, Minxiao Wang, Shiping Liu
  1. College of Life Sciences, University of Chinese Academy of Sciences,Beijing, 100049 China
  2. State Key Laboratory of Genome and Multi-omics Technologies, BGI Research,Hangzhou, 310030 China
  3. Key Laboratory of Spatial Omics of Zhejiang Province, BGI Research,Hangzhou, 310030 China
  4. Institute of Oceanology, Chinese Academy of Sciences,Qingdao, 266071 China
  5. Key Laboratory of Systems Health Science of Zhejiang Province, School of Life Science, Hangzhou Institute for Advanced Study, Hangzhou 310024; University of Chinese Academy of Sciences,Hangzhou, China
Institutions: University of Chinese Academy of Sciences (China); BGI Research (China); Chinese Academy of Sciences (China)
Journal: Scientific data, volume 13, issue 1, article 854
Dates: received 7 July 2025; accepted 19 March 2026; published online 10 April 2026
Type: Data paper · Language: English
License: CC BY
Identifiers: DOI 10.1038/s41597-026-07102-9 · PMID 41963377 · PMCID PMC13243523 · OpenAlex W7153068352
Open access: gold, a free copy (OpenAlex)
Status: data only
Categories: other (organism), methods / tools (subfield)
Keywords: Genome, Genomics, Genome informatics
MeSH: Chromosomes*, Genome*, Scyphozoa*, Animals, Datasets as Topic, DNA Transposable Elements, Molecular Sequence Annotation (* major topic)
Journal subjects: Data Descriptor
Topic: Marine Invertebrate Physiology and Ecology (Paleontology, Earth and Planetary Sciences), according to OpenAlex
Funding: National Key Research and Development Program of China (No. 2023YFC3108200) the Marine S&T Fund of Shandong Province for Pilot National Laboratory for Marine Science and Technology (Qingdao) (No. 2022QNLM030004); Zhejiang Science and Technology Department (No. 2024C03004) the Hangzhou Leading Innovation Team Project (No. TD2023003); National Natural Science Foundation of China (No. 42176136 and No. 42211540390) the “Future Partner Network” Project of the Chinese Academy of Sciences (No. 058GJHZ2022097FN) the Youth Innovation promotion Association Project, Chinese Academy of Sciences the Huiquan Scholar, Institute of Oceanology, Chinese Academy of Sciences to Song Feng
Citations: cited by 1 paper (Europe PMC); 42 references in the paper

Abstract

Aurelia coerulea (moon jellyfish), a radially symmetrical metazoan in the phylum Cnidaria, possesses key features pertinent to understanding the evolutionary origins of nervous systems. Here, we employed a combination of long-read sequencing, short-read sequencing, and Hi-C chromatin conformation capture techniques to generate a chromosome-level assembly of the A. coerulea genome. The final assembly comprises approximately 554.10 Mb distributed across 21 chromosomes, achieving a scaffold N50 of 24.06 Mb and demonstrating high completeness (protein BUSCO score: 93.0%). Approximately 71.48% of the genome consists of transposable elements. We identified 26,777 protein-coding genes, of which approximately 72.28% have been functionally annotated. This chromosome-level genome provides an essential resource for elucidating early neural evolution and advancing our understanding of cnidarian biology.

Reproduced under the paper's license (CC BY), from the paper cited above.

Code

The paper links to its data, not to its authors' code: see the Data section.

Code availability

The parameters of the software were default. No specific script was used in this work.

Reproduced under the paper's license (CC BY), from the paper cited above.

Tracing map

A tracing map links a paper to the code its authors published: this paper has none, so it has no map.

Data

Datasets cited

Data availability

All sequencing data, including WGS, PacBio, Hi-C, RNA-seq, as well as the assembly (JBPOCX000000000)38 have been deposited at the NCBI (National Centre for Biotechnology Information) repository under project PRJNA1284069, SRP59685039. The genome assembly and annotations of A. coerulea are also available at Figshare40.

Reproduced under the paper's license (CC BY), from the paper cited above.

Versions

The history of this record: each version stored by the harvester or made by a correction of its authors or of the maintainers of its code, and what changed in its facts. The texts of the paper (its abstract, its availability statements) are not part of it; versions that changed only those are not listed.

Version 1, 29 September 2026: the first record

Recorded: type, language, journal, volume, issue, pages, dates, 9 authors, 3 keywords, 7 MeSH terms, 3 funders, 38 references.

Cite

This paper

Hu, X., Guo, Y., Zhang, Z., Wang, L., Chen, D., Zhuang, Z., Wang, M., Liu, S., & Feng, S. (2026). Chromosome-level genome assembly and annotation of the moon jellyfish Aurelia coerulea. Scientific data, 13(1), 854. https://doi.org/10.1038/s41597-026-07102-9

BibTeX

@article{hu2026chromosome,
author = {Hu, Xinyue and Guo, Yang and Zhang, Ze and Wang, Liyuan and Chen, Duoyuan and Zhuang, Zhenkun and Wang, Minxiao and Liu, Shiping and Feng, Song},
title = {{Chromosome-level genome assembly and annotation of the moon jellyfish Aurelia coerulea}},
journal = {Scientific data},
year = {2026},
month = apr,
volume = {13},
number = {1},
pages = {854},
publisher = {Nature Publishing Group},
issn = {2052-4463},
doi = {10.1038/s41597-026-07102-9},
url = {https://doi.org/10.1038/s41597-026-07102-9},
pmid = {41963377},
pmcid = {PMC13243523}
}

RIS

TY - JOUR
AU - Hu, Xinyue
AU - Guo, Yang
AU - Zhang, Ze
AU - Wang, Liyuan
AU - Chen, Duoyuan
AU - Zhuang, Zhenkun
AU - Wang, Minxiao
AU - Liu, Shiping
AU - Feng, Song
TI - Chromosome-level genome assembly and annotation of the moon jellyfish Aurelia coerulea
T2 - Scientific data
J2 - Sci Data
PY - 2026
DA - 2026/04/10
VL - 13
IS - 1
SP - 854
SN - 2052-4463
PB - Nature Publishing Group
DO - 10.1038/s41597-026-07102-9
UR - https://doi.org/10.1038/s41597-026-07102-9
LA - en
ER -

CSL-JSON

{
"id": "10.1038/s41597-026-07102-9",
"type": "article-journal",
"title": "Chromosome-level genome assembly and annotation of the moon jellyfish Aurelia coerulea",
"container-title": "Scientific data",
"author": [
{
"family": "Hu",
"given": "Xinyue"
},
{
"family": "Guo",
"given": "Yang"
},
{
"family": "Zhang",
"given": "Ze"
},
{
"family": "Wang",
"given": "Liyuan"
},
{
"family": "Chen",
"given": "Duoyuan"
},
{
"family": "Zhuang",
"given": "Zhenkun"
},
{
"family": "Wang",
"given": "Minxiao"
},
{
"family": "Liu",
"given": "Shiping"
},
{
"family": "Feng",
"given": "Song"
}
],
"container-title-short": "Sci Data",
"volume": "13",
"issue": "1",
"page": "854",
"DOI": "10.1038/s41597-026-07102-9",
"PMID": "41963377",
"PMCID": "PMC13243523",
"ISSN": "2052-4463",
"publisher": "Nature Publishing Group",
"URL": "https://doi.org/10.1038/s41597-026-07102-9",
"language": "en",
"issued": {
"date-parts": [
[
2026,
4,
10
]
]
}
}

Similar papers

The papers with a page that share the most with this one: the tools found in their code, their categories, datasets, cited references and authors, the rarest counting most.

[1] doi:10.1186/s12864-026-12863-z [code]
Chromosome-level genome assembly of the nematophagous flatworm Luticola nematophagus: revealing molecular adaptations for predation and its biocontrol potential against nematode diseases.
Journal: BMC genomics
In common: other, 12 references
[2] doi:10.1093/nar/gkag544 [code]
Single-base resolution atlas reveals moderate conservation and regulatory diversity of m6A modifications across mammals.
Journal: Nucleic acids research
In common: 8 references
[3] doi:10.1186/s12864-026-12683-1
A new chromosome-level genome assembly for western painted turtle Chrysemys picta bellii, a model for extreme physiological adaptations.
Journal: BMC genomics
In common: other, 5 references
[4] doi:10.7554/elife.107393 [code]
Chromosome-scale genome assembly of the European common cuttlefish <i>Sepia officinalis</i>.
Journal: eLife
In common: other, 4 references
[5] doi:10.1371/journal.pbio.3003931 [code]
A single-cell transcriptomic atlas reveals the emergence of medusa-specific cell states in the scyphozoan Aurelia coerulea.
Journal: PLoS biology
In common: 4 references
[6] doi:10.1093/molbev/msag128 [code]
Single-cell analyses of tissue regeneration in two true jellyfish.
Journal: Molecular biology and evolution
In common: other, 3 references
[7] doi:10.1038/s41467-026-71759-4 [code]
CellNiche represents cellular microenvironments in atlas-scale spatial omics data with contrastive learning.
Journal: Nature communications
In common: author Shiping Liu
[8] doi:10.1371/journal.pbio.3003803 [code]
The anti-neural role of BMP signaling is a consequence of its ancestral function in dorsoventral patterning.
Journal: PLoS biology
In common: other, 2 references
[9] doi:10.1126/sciadv.aeb8034 [code]
Deciphering the ancestral mechanisms of neural regeneration through single-cell analyses of jellyfish rhopalium repair.
Journal: Science advances
In common: other, 2 references
[10] doi:10.7554/elife.89001 [code]
Human-specific lncRNAs contributed critically to human evolution by distinctly regulating gene expression.
Journal: eLife
In common: 3 references

Contribute

The authors of this paper can claim it, correct its record and validate its tracing map, and the maintainers of its code (its owner, or a public member of its organization) correct what it says of their repository; anyone signed in can ask for its removal. Every request goes to OSCR's own machine, which answers it; your account page follows them.

Sign in with ORCID to claim this paper as one of its authors, correct its record or validate its tracing map: when the paper's metadata lists your ORCID iD, you are recognized at once. Maintainers of its code: sign in with GitHub, then claim the repository on your account page.

Request its removal

To ask OSCR to remove this record, the copies of its authors' scripts or its tracing map, use the removal request page: signed in, you say who you are, what to remove and why, then review and confirm the request. Published rules decide every request (how).

Discussion, reproductions, activity

Discussion: questions and error reports about this paper and its code, from signed-in readers and its authors. It opens with sign-in.

Reproductions: reports from readers who ran the authors' code: what they reproduced, with which environment, commit and data. It opens with sign-in.

Activity: what happens around this paper: new versions of its record, its map's validation, discussions and reproductions. It opens with sign-in.