Persistence of vestibular function in the absence of glutamatergic transmission from hair cells.
Overview
- Experimental Otology Group, InnerEarLab, Department of Otolaryngology, Institute for Auditory Neuroscience, University Medical Center Göttingen, Göttingen, Germany
- International Max Planck Research School (IMPRS) for Neuroscience, Göttingen, Germany
- Department of Otolaryngology – Head and Neck Surgery, Washington University School of Medicine, St. Louis, MO USA
- Department of Neurology, Washington University School of Medicine, St. Louis, MO USA
- Departments of Neurobiology and Otolaryngology, Pittsburgh Center for Pain Research, University of Pittsburgh, Pittsburgh, PA USA
- Department of Otolaryngology, Department of Neuroscience, University of Rochester, Rochester, NY USA
- Department of Psychiatry, Washington University School of Medicine, St. Louis, MO USA
- Intellectual and Developmental Disability Research Center, Washington University School of Medicine, St. Louis, MO USA
- Institute for Auditory Neuroscience, Auditory Neuroscience Group, Max Planck Institute for Multidisciplinary Sciences, Göttingen, Germany
- Collaborative Research Center 889, University of Göttingen, Göttingen, Germany
- Multiscale Bioimaging Cluster of Excellence (MBExC), University of Göttingen, Göttingen, Germany
Abstract
Quantal synaptic transmission in vestibular endorgans is glutamatergic. Here, we investigated the vestibular phenotype of deaf Vglut3−/
Supplementary Information: The online version contains supplementary material available at 10.1038/
Reproduced under the paper's license (CC BY), from the paper cited above.
Code
The paper links to its data and to no code of its authors: see the Data section.
Tracing map
A tracing map links a paper to the code its authors published: this paper has none, so it has no map.
Data
Datasets cited
- geo:GSE115934, at NCBI GEO; found in “Data availability”
Data availability
All datasets are available from the corresponding authors upon request. Vglut1 and 2 mRNA expression data in Supplemental Figure 2a is available at gEAR (https://
Reproduced under the paper's license (CC BY), from the paper cited above.
Versions
The history of this record: each version stored by the harvester or made by a correction of its authors or of the maintainers of its code, and what changed in its facts. The texts of the paper (its abstract, its availability statements) are not part of it; versions that changed only those are not listed.
Version 1, 30 September 2026: the first record
Recorded: type, language, journal, volume, issue, pages, dates, 17 authors, 7 keywords, 9 MeSH terms, 1 funder, 105 references, 7 RRIDs.
Cite
This paper
Mukhopadhyay, M., Modgekar, R., Yang-Hood, A., Ohlemiller, K. K., Militchin, V., Xiao, M., Shen, Z., Rensing, N. R., Wong, M., Lee, S. J., Seal, R. P., Holt, J. C., Warchol, M. E., Maloney, S. E., Yuede, C. M., Rutherford, M. A., & Pangrsic, T. (2026). Persistence of vestibular function in the absence of glutamatergic transmission from hair cells. Scientific reports, 16(1), 14550. https://
BibTeX
@article{mukhopadhyay202
author = {Mukhopadhyay, Mohona and Modgekar, Ruchi and Yang-Hood, Aizhen and Ohlemiller, Kevin K and Militchin, Valentin and Xiao, Maolei and Shen, Zhijun and Rensing, Nicholas R and Wong, Michael and Lee, Suh Jin and Seal, Rebecca P and Holt, Joseph C and Warchol, Mark E and Maloney, Susan E and Yuede, Carla M and Rutherford, Mark A and Pangrsic, Tina},
title = {{Persistence of vestibular function in the absence of glutamatergic transmission from hair cells}},
journal = {Scientific reports},
year = {2026},
month = mar,
volume = {16},
number = {1},
pages = {14550},
publisher = {Nature Publishing Group},
issn = {2045-2322},
doi = {10.1038/
url = {https://
pmid = {41866362},
pmcid = {PMC13153426}
}
RIS
TY - JOUR
AU - Mukhopadhyay, Mohona
AU - Modgekar, Ruchi
AU - Yang-Hood, Aizhen
AU - Ohlemiller, Kevin K
AU - Militchin, Valentin
AU - Xiao, Maolei
AU - Shen, Zhijun
AU - Rensing, Nicholas R
AU - Wong, Michael
AU - Lee, Suh Jin
AU - Seal, Rebecca P
AU - Holt, Joseph C
AU - Warchol, Mark E
AU - Maloney, Susan E
AU - Yuede, Carla M
AU - Rutherford, Mark A
AU - Pangrsic, Tina
TI - Persistence of vestibular function in the absence of glutamatergic transmission from hair cells
T2 - Scientific reports
J2 - Sci Rep
PY - 2026
DA - 2026/
VL - 16
IS - 1
SP - 14550
SN - 2045-2322
PB - Nature Publishing Group
DO - 10.1038/
UR - https://
LA - en
ER -
CSL-JSON
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