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Glucose-driven intra- and inter-islet beta cell synchronization in pancreatic tissue slices.

Code ↔ Paper

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Paper

Loaded from Europe PMC by your browser, not stored by OSCR: doi.org · Europe PMC

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The authors' code

Python · 32 lines · 731 B · MIT

  1. """
  2. Entry point for the analysis
  3. """
  5. # pylint: disable=W0702
  6. from methods.islet import Islet
  7. from methods.router import Router
  9. islet = Islet()
  10. router = Router()
  12. routes = {
  13. 1: islet.first_responder_analysis,
  14. 2: islet.filter_traces,
  15. 3: islet.smooth_traces,
  16. 4: islet.binarize_traces,
  17. 5: islet.exclude_traces,
  18. 6: islet.corr_coact_analysis,
  19. 7: islet.cell_activity_analysis,
  20. 8: islet.wave_anaylsis,
  21. 99: islet.save_configs_to_data,
  22. 'load': islet.load_data,
  23. 'bundle': islet.bundle_data
  24. }
  26. islet.load_configs()
  27. router.register_routes(routes)
  28. router.print_options()
  29. while True:
  30. router.parse_input(input('Select analysis step [number/string]: '))
  31. islet.load_configs()
  32. router.route()

run-checkpoint.py at commit 3d62615, under MIT · at the source

Overview

Authors: Lidija Križančić Bombek1, Nika Polšak1, Jurij Dolenšek1, Andraž Stožer1, Marko Gosak1,2,3
ORCID iDs: Marko Gosak
  1. Faculty of Medicine, Institute of Physiology, University of Maribor,Maribor, Slovenia
  2. Department of Physics, Faculty of Natural Sciences and Mathematics, University of Maribor,Maribor, Slovenia
  3. Alma Mater Europaea University,Maribor, Slovenia
Institutions: University of Maribor (Slovenia); Alma Mater Europaea (Slovenia)
Journal: Scientific reports, volume 16, issue 1, article 15808
Dates: received 22 December 2025; accepted 26 March 2026; published online 2 April 2026
Type: Research article · Language: English
License: CC BY-NC-ND
Identifiers: DOI 10.1038/s41598-026-46512-y · PMID 41927867 · PMCID PMC13194678 · OpenAlex W7148526044
Open access: gold, a free copy (OpenAlex)
Status: code verified
Categories: mouse (organism), cellular / molecular (subfield)
Methods: Spectral & time-frequency, Connectivity, Graphs, Statistics, fMRI & imaging, Single-unit activity, calcium imaging
Keywords: Endocrinology, Neuroscience, Physiology
MeSH: Glucose*, Insulin-Secreting Cells*, Islets of Langerhans*, Pancreas*, Animals, Calcium, Calcium Signaling, Insulin, Insulin Secretion, Mice (* major topic)
Topic: Pancreatic function and diabetes (Surgery, Medicine), according to OpenAlex
Funding: Javna Agencija za Raziskovalno Dejavnost RS (P3-0396, I0-0029, J3-60062, L3-60156)
Citations: cited by 2 papers (Europe PMC); 77 references in the paper

Abstract

The abstract is not reproduced here: the paper's license (CC BY-NC-ND) does not allow it. Read it in the paper, at the publisher or on Europe PMC.

Repository

Its files are read in the Code ↔ Paper reader above.

MarkoSterk/beta_cell_analysis_suite

License: MIT
State: the link answers, verified on 28 September 2026
Evidence: files inventoried
Commit: 3d626158e352baba31f9e201e400ddbb7226f33d, 25 July 2024
Languages: Python (26)
Size: 39 files, 26 scripts
Software Heritage: not archived
Found in: “Code availability”
Holds: README, license file, CITATION.cff, environment (requirements.txt, requirements_mac.txt)
Not found: tests, continuous integration, documentation
Tools: NumPy (20 files), Matplotlib (13 files), SciPy (4 files), NetworkX (3 files), pandas (1 file), seaborn (1 file)
Availability: 1 check, the latest on 28 September 2026: the link answers
  • 28 September 2026: the link answers
28 files
At the source: github.com/MarkoSterk/beta_cell_analysis_suite

Code availability statement

The paper has a code availability statement. Its license (CC BY-NC-ND) does not allow reproducing it here; in short, from what the harvester recognized in it:

Read it in the paper: doi.org/10.1038/s41598-026-46512-y.

Tracing map

Proposed by the machine: these links were found in the paper and verified at the source, without human review. The map will receive a Zenodo DOI once one of the paper's authors has validated it with their ORCID.

What the map holds:

  • 1 repository of the authors' code, each at its verified commit, with its license and how the link was found in the paper;
  • 26 scripts, each with its path and the digest of its content;
  • no match between paragraphs and code yet;
  • neither the text of the paper nor the code itself.

Its JSON (tracing-map.json) is deposited on Zenodo with its DOI once the map is validated.

Data

No dataset and no data link were found in the paper.

Data availability statement

The paper has a data availability statement. Its license (CC BY-NC-ND) does not allow reproducing it here; in short, from what the harvester recognized in it:

  • no repository, dataset or request procedure was recognized in it

Read it in the paper: doi.org/10.1038/s41598-026-46512-y.

Versions

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Version 1, 28 September 2026: the first record

Recorded: type, language, journal, volume, issue, pages, dates, 5 authors, 3 keywords, 10 MeSH terms, 1 funder, 76 references.

Cite

This paper

Križančić Bombek, L., Polšak, N., Dolenšek, J., Stožer, A., & Gosak, M. (2026). Glucose-driven intra- and inter-islet beta cell synchronization in pancreatic tissue slices. Scientific reports, 16(1), 15808. https://doi.org/10.1038/s41598-026-46512-y

BibTeX

@article{krizancicbombek2026glucose,
author = {Križančić Bombek, Lidija and Polšak, Nika and Dolenšek, Jurij and Stožer, Andraž and Gosak, Marko},
title = {{Glucose-driven intra- and inter-islet beta cell synchronization in pancreatic tissue slices}},
journal = {Scientific reports},
year = {2026},
month = apr,
volume = {16},
number = {1},
pages = {15808},
publisher = {Nature Publishing Group},
issn = {2045-2322},
doi = {10.1038/s41598-026-46512-y},
url = {https://doi.org/10.1038/s41598-026-46512-y},
pmid = {41927867},
pmcid = {PMC13194678}
}

RIS

TY - JOUR
AU - Križančić Bombek, Lidija
AU - Polšak, Nika
AU - Dolenšek, Jurij
AU - Stožer, Andraž
AU - Gosak, Marko
TI - Glucose-driven intra- and inter-islet beta cell synchronization in pancreatic tissue slices
T2 - Scientific reports
J2 - Sci Rep
PY - 2026
DA - 2026/04/02
VL - 16
IS - 1
SP - 15808
SN - 2045-2322
PB - Nature Publishing Group
DO - 10.1038/s41598-026-46512-y
UR - https://doi.org/10.1038/s41598-026-46512-y
LA - en
ER -

CSL-JSON

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"id": "10.1038/s41598-026-46512-y",
"type": "article-journal",
"title": "Glucose-driven intra- and inter-islet beta cell synchronization in pancreatic tissue slices",
"container-title": "Scientific reports",
"author": [
{
"family": "Križančić Bombek",
"given": "Lidija"
},
{
"family": "Polšak",
"given": "Nika"
},
{
"family": "Dolenšek",
"given": "Jurij"
},
{
"family": "Stožer",
"given": "Andraž"
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{
"family": "Gosak",
"given": "Marko"
}
],
"container-title-short": "Sci Rep",
"volume": "16",
"issue": "1",
"page": "15808",
"DOI": "10.1038/s41598-026-46512-y",
"PMID": "41927867",
"PMCID": "PMC13194678",
"ISSN": "2045-2322",
"publisher": "Nature Publishing Group",
"URL": "https://doi.org/10.1038/s41598-026-46512-y",
"language": "en",
"issued": {
"date-parts": [
[
2026,
4,
2
]
]
}
}

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