OSCR

Neurovascular and inflammatory effects of biperiden in the acute phase of moderate traumatic brain injury: evidence from a non-human primate model.

Overview

Authors: Viviam Sanabria1, Christiane Gimenes1, Simone Romariz1, Amarildo Souza Gois2, Matheus B Braga1, Michele Longoni Calió2,3, Juliana Lima Willers2, Maira L Foresti2,3, Luiz Eugênio Mello2,3, Beatriz M Longo1
  1. Laboratory of Neurophysiology, Department of Physiology, Universidade Federal de São Paulo, São Paulo, Brazil
  2. Laboratory of Neurobiology, Department of Physiology, Universidade Federal de São Paulo, São Paulo, Brazil
  3. Instituto D’Or de Pesquisa e Ensino, São Paulo, São Paulo, Brazil
Institutions: Universidade Federal de São Paulo (Brazil); D’Or Institute for Research and Education (Brazil)
Journal: Scientific reports, volume 16, issue 1, article 27889
Dates: received 30 March 2026; accepted 11 May 2026; published online 18 June 2026
Type: Research article · Language: English
License: CC BY-NC-ND
Identifiers: DOI 10.1038/s41598-026-53148-5 · PMID 42315867 · PMCID PMC13547420 · OpenAlex W7165124348
Open access: gold, a free copy (OpenAlex)
Status: data only
Categories: other (modality), human (organism), non-human primate (organism), traumatic brain injury (population)
Methods: Statistics, Smoothing, state filtering, decompositions, Machine learning, Connectivity, fMRI & imaging, Physiology & signal measures
Keywords: Acute, Glia, Vessels, Biperiden, Hematomas, SIMOA, Neurology, Neuroscience
MeSH: Brain Injuries, Traumatic*, Dipyridamole*, Muscarinic Antagonists*, Neuroprotective Agents*, Animals, Callithrix, Disease Models, Animal, Inflammation, Male, Piperidines (* major topic)
Topic: Traumatic Brain Injury and Neurovascular Disturbances (Neurology, Medicine), according to OpenAlex
Funding: Fundação de Amparo à Pesquisa do Estado de São Paulo (2017/05242-3, 2022/00249-8, 2018/24561-5); Conselho Nacional de Desenvolvimento Científico e Tecnológico (311619/2019-3)
Citations: not cited yet (Europe PMC); 64 references in the paper

Abstract

The abstract is not reproduced here: the paper's license (CC BY-NC-ND) does not allow it. Read it in the paper, at the publisher or on Europe PMC.

Code

The paper links to its data, not to its authors' code: see the Data section.

Tracing map

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Data

Datasets cited

Data availability statement

The paper has a data availability statement. Its license (CC BY-NC-ND) does not allow reproducing it here; in short, from what the harvester recognized in it:

  • it points to a dataset: OSF zq5am
  • it says that the data are available on request

Read it in the paper: doi.org/10.1038/s41598-026-53148-5.

Versions

The history of this record: each version stored by the harvester or made by a correction of its authors or of the maintainers of its code, and what changed in its facts. The texts of the paper (its abstract, its availability statements) are not part of it; versions that changed only those are not listed.

Version 1, 27 September 2026: the first record

Recorded: type, language, journal, volume, issue, pages, dates, 10 authors, 8 keywords, 10 MeSH terms, 2 funders, 63 references.

Cite

This paper

Sanabria, V., Gimenes, C., Romariz, S., Gois, A. S., Braga, M. B., Calió, M. L., Willers, J. L., Foresti, M. L., Mello, L. E., & Longo, B. M. (2026). Neurovascular and inflammatory effects of biperiden in the acute phase of moderate traumatic brain injury: evidence from a non-human primate model. Scientific reports, 16(1), 27889. https://doi.org/10.1038/s41598-026-53148-5

BibTeX

@article{sanabria2026neurovascular,
author = {Sanabria, Viviam and Gimenes, Christiane and Romariz, Simone and Gois, Amarildo Souza and Braga, Matheus B and Calió, Michele Longoni and Willers, Juliana Lima and Foresti, Maira L and Mello, Luiz Eugênio and Longo, Beatriz M},
title = {{Neurovascular and inflammatory effects of biperiden in the acute phase of moderate traumatic brain injury: evidence from a non-human primate model}},
journal = {Scientific reports},
year = {2026},
month = jun,
volume = {16},
number = {1},
pages = {27889},
publisher = {Nature Publishing Group},
issn = {2045-2322},
doi = {10.1038/s41598-026-53148-5},
url = {https://doi.org/10.1038/s41598-026-53148-5},
pmid = {42315867},
pmcid = {PMC13547420}
}

RIS

TY - JOUR
AU - Sanabria, Viviam
AU - Gimenes, Christiane
AU - Romariz, Simone
AU - Gois, Amarildo Souza
AU - Braga, Matheus B
AU - Calió, Michele Longoni
AU - Willers, Juliana Lima
AU - Foresti, Maira L
AU - Mello, Luiz Eugênio
AU - Longo, Beatriz M
TI - Neurovascular and inflammatory effects of biperiden in the acute phase of moderate traumatic brain injury: evidence from a non-human primate model
T2 - Scientific reports
J2 - Sci Rep
PY - 2026
DA - 2026/06/18
VL - 16
IS - 1
SP - 27889
SN - 2045-2322
PB - Nature Publishing Group
DO - 10.1038/s41598-026-53148-5
UR - https://doi.org/10.1038/s41598-026-53148-5
LA - en
ER -

CSL-JSON

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