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Cellular landscape and diagnostic value of TROP2 in cerebrospinal fluid of lung adenocarcinoma leptomeningeal metastases.

Overview

Authors: Zhe Wang1,2, Jie Luo3, Yuexinzi Jin1,4, Ting Wang1,4, Yuan Mu1,4, Jinping Liu1,4, Huanyu Ju1,4, Yuqing Wu1,4, Qingjian Ou5, Ming Guan6, Haoyu Ruan1,4
ORCID iDs: Qingjian Ou
  1. Department of Laboratory Medicine, The First Affiliated Hospital with Nanjing Medical University,Nanjing, China
  2. Department of Physiology, Second Military Medical University,Shanghai, China
  3. Department of Cardiology, Nanjing First Hospital, Nanjing Medical University,Nanjing, China
  4. Branch of National key Clinical Research Center for Laboratory Medicine, Nanjing, China
  5. Laboratory of Clinical and Visual Sciences, Tongji hospital, School of Medicine, Tongji University,Shanghai, China
  6. Department of Laboratory Medicine, Huashan Hospital, Fudan University,Shanghai, China
Institutions: Jiangsu Province Hospital (China); Second Military Medical University (China); Nanjing Medical University (China); Tongji University (China); Fudan University (China)
Journal: NPJ precision oncology, volume 10, issue 1, article 183
Dates: received 3 June 2025; accepted 7 March 2026; published online 24 March 2026
Type: Research article · Language: English
License: CC BY-NC-ND
Identifiers: DOI 10.1038/s41698-026-01379-0 · PMID 41876785 · PMCID PMC13187205 · OpenAlex W7140233531
Open access: gold, a free copy (OpenAlex)
Status: data only (how the code is found and verified)
Categories: genetics / omics (modality), human (organism), other condition (population), clinical / translational (subfield)
Methods: Statistics, Smoothing, state filtering, decompositions
Keywords: CNS cancer, Lung cancer, Metastasis, Tumour angiogenesis, Tumour biomarkers, Tumour heterogeneity, Biomarkers
Topic: Brain Metastases and Treatment (Oncology, Medicine), according to OpenAlex
Funding: Shanghai Sailing Program (23YF1457700); National Natural Science Foundation of China (82202610, 82502175, 82103328, 82272429, 82102489)
Citations: not cited yet (Europe PMC); 72 references in the paper

Abstract

The abstract is not reproduced here: the paper's license (CC BY-NC-ND) does not allow it. Read it in the paper, at the publisher or on Europe PMC.

Code

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Data

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Data availability statement

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Read it in the paper: doi.org/10.1038/s41698-026-01379-0.

Versions

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Version 1, 30 September 2026: the first record

Recorded: type, language, journal, volume, issue, pages, dates, 11 authors, 7 keywords, 2 funders, 72 references.

Cite

This paper

Wang, Z., Luo, J., Jin, Y., Wang, T., Mu, Y., Liu, J., Ju, H., Wu, Y., Ou, Q., Guan, M., & Ruan, H. (2026). Cellular landscape and diagnostic value of TROP2 in cerebrospinal fluid of lung adenocarcinoma leptomeningeal metastases. NPJ precision oncology, 10(1), 183. https://doi.org/10.1038/s41698-026-01379-0

BibTeX

@article{wang2026cellular,
author = {Wang, Zhe and Luo, Jie and Jin, Yuexinzi and Wang, Ting and Mu, Yuan and Liu, Jinping and Ju, Huanyu and Wu, Yuqing and Ou, Qingjian and Guan, Ming and Ruan, Haoyu},
title = {{Cellular landscape and diagnostic value of TROP2 in cerebrospinal fluid of lung adenocarcinoma leptomeningeal metastases}},
journal = {NPJ precision oncology},
year = {2026},
month = mar,
volume = {10},
number = {1},
pages = {183},
publisher = {Nature Publishing Group},
issn = {2397-768X},
doi = {10.1038/s41698-026-01379-0},
url = {https://doi.org/10.1038/s41698-026-01379-0},
pmid = {41876785},
pmcid = {PMC13187205}
}

RIS

TY - JOUR
AU - Wang, Zhe
AU - Luo, Jie
AU - Jin, Yuexinzi
AU - Wang, Ting
AU - Mu, Yuan
AU - Liu, Jinping
AU - Ju, Huanyu
AU - Wu, Yuqing
AU - Ou, Qingjian
AU - Guan, Ming
AU - Ruan, Haoyu
TI - Cellular landscape and diagnostic value of TROP2 in cerebrospinal fluid of lung adenocarcinoma leptomeningeal metastases
T2 - NPJ precision oncology
J2 - NPJ Precis Oncol
PY - 2026
DA - 2026/03/24
VL - 10
IS - 1
SP - 183
SN - 2397-768X
PB - Nature Publishing Group
DO - 10.1038/s41698-026-01379-0
UR - https://doi.org/10.1038/s41698-026-01379-0
LA - en
ER -

CSL-JSON

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