OSCR

Hippocampal astrocytic GAT-3 blockade impairs protein synthesis and spatial memory dynamics.

Overview

Authors: Juan G Riboldi1,2,3, Josefina Iribarne1,2,3, Matias M Renfijes2,4, Lionel M Igaz5,6, Diego Moncada7,8, Haydee Viola1,2,3
ORCID iDs: Juan G Riboldi, Lionel M Igaz, Haydee Viola
  1. Departamento de Fisiología, Biología Molecular y Celular “Dr. Héctor Maldonado” (FBMC), Universidad de Buenos Aires, Facultad de Ciencias Exactas y Naturales, Buenos Aires, Argentina
  2. CONICET - Universidad de Buenos Aires, Instituto de Biología Celular y Neurociencias “Profesor Eduardo De Robertis” (IBCN), Buenos Aires, Argentina
  3. Instituto Tecnológico de Buenos Aires (ITBA), Buenos Aires, Argentina
  4. Facultad de Medicina, Universidad de Buenos Aires, Buenos Aires, Argentina
  5. Departamento de Ciencias Fisiológicas. Grupo de Neurociencias de Sistemas, Universidad de Buenos Aires, Facultad de Ciencias Médicas, Buenos Aires, Argentina
  6. CONICET - Universidad de Buenos Aires. Instituto de Fisiología y Biofísica Bernardo Houssay (IFIBIO Houssay), Buenos Aires, Argentina
  7. Laboratorio de Neurofisiología de la Memoria, Instituto de Biología Celular y Neurociencia, Facultad de Medicina (UBA/CONICET) - Instituto Tecnológico de Buenos Aires (ITBA), Buenos Aires, Argentina
  8. Centro Integrativo de Biología y Química Aplicada, Universidad Bernardo O’Higgins, Santiago, Chile
Institutions: Consejo Nacional de Investigaciones Científicas y Técnicas (Argentina); Universidad de Buenos Aires (Argentina); Instituto Tecnológico de Buenos Aires (ITBA) (Argentina); Universidad Bernardo O'Higgins (Chile)
Journal: Communications biology, volume 9, issue 1, article 934
Dates: received 11 September 2025; accepted 21 April 2026; published online 6 May 2026
Type: Research article · Language: English
License: CC BY-NC-ND
Identifiers: DOI 10.1038/s42003-026-10159-2 · PMID 42086667 · PMCID PMC13350875 · OpenAlex W7160278996
Open access: gold, a free copy (OpenAlex)
Status: data only
Categories: rat (organism), cellular / molecular (subfield)
Methods: Spectral & time-frequency, Statistics
Keywords: Hippocampus, Astrocyte
MeSH: Astrocytes*, GABA Plasma Membrane Transport Proteins*, Hippocampus*, Protein Biosynthesis*, Spatial Memory*, Animals, Female, Rats, Rats, Wistar (* major topic)
Topic: Neuroscience and Neuropharmacology Research (Cellular and Molecular Neuroscience, Neuroscience), according to OpenAlex
Funding: Ministry of Science, Technology and Productive Innovation, Argentina | Agencia Nacional de Promoción Científica y Tecnológica (National Agency for Science and Technology, Argentina) (2019-00967)
Citations: not cited yet (Europe PMC); 80 references in the paper

Abstract

The abstract is not reproduced here: the paper's license (CC BY-NC-ND) does not allow it. Read it in the paper, at the publisher or on Europe PMC.

Code

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Data

Datasets cited

Data availability statement

The paper has a data availability statement. Its license (CC BY-NC-ND) does not allow reproducing it here; in short, from what the harvester recognized in it:

Read it in the paper: doi.org/10.1038/s42003-026-10159-2.

Versions

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Version 1, 28 September 2026: the first record

Recorded: type, language, journal, volume, issue, pages, dates, 6 authors, 2 keywords, 9 MeSH terms, 1 funder, 78 references.

Cite

This paper

Riboldi, J. G., Iribarne, J., Renfijes, M. M., Igaz, L. M., Moncada, D., & Viola, H. (2026). Hippocampal astrocytic GAT-3 blockade impairs protein synthesis and spatial memory dynamics. Communications biology, 9(1), 934. https://doi.org/10.1038/s42003-026-10159-2

BibTeX

@article{riboldi2026hippocampal,
author = {Riboldi, Juan G and Iribarne, Josefina and Renfijes, Matias M and Igaz, Lionel M and Moncada, Diego and Viola, Haydee},
title = {{Hippocampal astrocytic GAT-3 blockade impairs protein synthesis and spatial memory dynamics}},
journal = {Communications biology},
year = {2026},
month = may,
volume = {9},
number = {1},
pages = {934},
publisher = {Nature Publishing Group},
issn = {2399-3642},
doi = {10.1038/s42003-026-10159-2},
url = {https://doi.org/10.1038/s42003-026-10159-2},
pmid = {42086667},
pmcid = {PMC13350875}
}

RIS

TY - JOUR
AU - Riboldi, Juan G
AU - Iribarne, Josefina
AU - Renfijes, Matias M
AU - Igaz, Lionel M
AU - Moncada, Diego
AU - Viola, Haydee
TI - Hippocampal astrocytic GAT-3 blockade impairs protein synthesis and spatial memory dynamics
T2 - Communications biology
J2 - Commun Biol
PY - 2026
DA - 2026/05/06
VL - 9
IS - 1
SP - 934
SN - 2399-3642
PB - Nature Publishing Group
DO - 10.1038/s42003-026-10159-2
UR - https://doi.org/10.1038/s42003-026-10159-2
LA - en
ER -

CSL-JSON

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"PMCID": "PMC13350875",
"ISSN": "2399-3642",
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"language": "en",
"issued": {
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