OSCR

Educational attainment mitigates hippocampal-related episodic memory decline in individuals at risk of Alzheimer's disease.

Overview

Authors: Annalise Aleta LaPlume1,2,3, Samira Mellah4, the Consortium for the early identification of Alzheimer's disease‐Quebec (CIMA‐Q), Maria Natasha Rajah2,3, Sylvie Belleville4,5
ORCID iDs: Annalise Aleta LaPlume
  1. Department of Psychology Trent University Peterborough Ontario Canada
  2. Department of Psychiatry McGill University Montreal Ontario Canada
  3. Department of Psychology Toronto Metropolitan University Toronto Ontario Canada
  4. Research Center, Institut Universitaire de Geriatrie de Montréal Montreal Quebec Canada
  5. Department of Psychology Université de Montréal Montreal Quebec Canada
Institutions: McGill University (Canada); Toronto Metropolitan University (Canada); Trent University (Canada); Institut Universitaire de Gériatrie de Montréal (Canada); Université de Montréal (Canada)
Journal: Journal of neuropsychology, volume 20, issue 2, pages 394-409
Dates: received 31 January 2024; accepted 11 February 2026; published online 24 March 2026; in print June 2026
Type: Research article · Language: English
License: CC BY-NC-ND
Identifiers: DOI 10.1111/jnp.70039 · PMID 41874386 · PMCID PMC13250359 · OpenAlex W7140210861
Open access: hybrid, a free copy (OpenAlex)
Status: code on request (how the code is found and verified)
Categories: structural MRI / diffusion (modality), human (organism), Alzheimer's / dementia (population), cognitive (subfield)
Methods: Statistics
Keywords: Alzheimer's disease, associative memory, cognition, cognitive reserve, education, episodic memory, hippocampus
MeSH: Alzheimer Disease*, Educational Status*, Hippocampus*, Memory Disorders*, Memory, Episodic*, Aged, Aged, 80 and over, Cognitive Reserve, Female, Humans, Magnetic Resonance Imaging, Male, Neuropsychological Tests, Organ Size (* major topic)
Topic: Dementia and Cognitive Impairment Research (Psychiatry and Mental health, Medicine), according to OpenAlex
Funding: Gouvernement du Canada | Canadian Institutes of Health Research (IRSC); Fondation Courtois; Réseau québécois de recherche sur le vieillissement; Fonds de recherche du Québec (FRQ); Fonds de Recherche du Québec - Santé; Quebec Consortium for the early identification of Alzheimer's disease (CIMA‐Q); Canadian Consortium on Neurodegeneration in Aging (CCNA); Fondation Famille Lemaire; Natural Sciences and Engineering Research Council of Canada
Citations: not cited yet (Europe PMC); 71 references in the paper

Abstract

The abstract is not reproduced here: the paper's license (CC BY-NC-ND) does not allow it. Read it in the paper, at the publisher or on Europe PMC.

Code

The paper says that its authors' code is available on request: it was not published with the paper, so there is nothing to verify.

The paper's code and data availability statement is in the Data section.

Tracing map

A tracing map links a paper to the code its authors published: this paper has none (its code is available on request), so it has no map.

Data

No dataset and no data link were found in the paper.

Code and data availability statement

The paper has a code and data availability statement. Its license (CC BY-NC-ND) does not allow reproducing it here; in short, from what the harvester recognized in it:

  • it says that the data are available on request
  • it says that the code is available on request

Read it in the paper: doi.org/10.1111/jnp.70039.

Versions

The history of this record: each version stored by the harvester or made by a correction of its authors or of the maintainers of its code, and what changed in its facts. The texts of the paper (its abstract, its availability statements) are not part of it; versions that changed only those are not listed.

Version 1, 30 September 2026: the first record

Recorded: type, language, journal, volume, issue, pages, dates, 5 authors, 7 keywords, 14 MeSH terms, 9 funders, 66 references.

Cite

This paper

LaPlume, A. A., Mellah, S., the Consortium for the early identification of Alzheimer's disease‐Quebec (CIMA‐Q), Rajah, M. N., & Belleville, S. (2026). Educational attainment mitigates hippocampal-related episodic memory decline in individuals at risk of Alzheimer's disease. Journal of neuropsychology, 20(2), 394-409. https://doi.org/10.1111/jnp.70039

BibTeX

@article{laplume2026educational,
author = {LaPlume, Annalise Aleta and Mellah, Samira and {the Consortium for the early identification of Alzheimer's disease‐Quebec (CIMA‐Q)} and Rajah, Maria Natasha and Belleville, Sylvie},
title = {{Educational attainment mitigates hippocampal-related episodic memory decline in individuals at risk of Alzheimer's disease}},
journal = {Journal of neuropsychology},
year = {2026},
month = mar,
volume = {20},
number = {2},
pages = {394--409},
publisher = {Wiley},
issn = {1748-6645},
doi = {10.1111/jnp.70039},
url = {https://doi.org/10.1111/jnp.70039},
pmid = {41874386},
pmcid = {PMC13250359}
}

RIS

TY - JOUR
AU - LaPlume, Annalise Aleta
AU - Mellah, Samira
AU - the Consortium for the early identification of Alzheimer's disease‐Quebec (CIMA‐Q)
AU - Rajah, Maria Natasha
AU - Belleville, Sylvie
TI - Educational attainment mitigates hippocampal-related episodic memory decline in individuals at risk of Alzheimer's disease
T2 - Journal of neuropsychology
J2 - J Neuropsychol
PY - 2026
DA - 2026/03/24
VL - 20
IS - 2
SP - 394
EP - 409
SN - 1748-6645
PB - Wiley
DO - 10.1111/jnp.70039
UR - https://doi.org/10.1111/jnp.70039
LA - en
ER -

CSL-JSON

{
"id": "10.1111/jnp.70039",
"type": "article-journal",
"title": "Educational attainment mitigates hippocampal-related episodic memory decline in individuals at risk of Alzheimer's disease",
"container-title": "Journal of neuropsychology",
"author": [
{
"family": "LaPlume",
"given": "Annalise Aleta"
},
{
"family": "Mellah",
"given": "Samira"
},
{
"literal": "the Consortium for the early identification of Alzheimer's disease‐Quebec (CIMA‐Q)"
},
{
"family": "Rajah",
"given": "Maria Natasha"
},
{
"family": "Belleville",
"given": "Sylvie"
}
],
"container-title-short": "J Neuropsychol",
"volume": "20",
"issue": "2",
"page": "394-409",
"DOI": "10.1111/jnp.70039",
"PMID": "41874386",
"PMCID": "PMC13250359",
"ISSN": "1748-6645",
"publisher": "Wiley",
"URL": "https://doi.org/10.1111/jnp.70039",
"language": "en",
"issued": {
"date-parts": [
[
2026,
3,
24
]
]
}
}

Similar papers

The papers with a page that share the most with this one: the tools found in their code, their categories, datasets, cited references and authors, the rarest counting most.

[1] doi:10.1093/brain/awac392 [code]
Educational attainment, structural brain reserve and Alzheimer's disease: a Mendelian randomization analysis.
Journal: Brain : a journal of neurology
In common: Alzheimer's / dementia, structural MRI / diffusion, 9 references
[2] doi:10.1038/s41467-026-73071-7 [code]
Brain maintenance biomarkers from structural and functional interactions in aging and neurodegeneration.
Journal: Nature communications
In common: Alzheimer's / dementia, structural MRI / diffusion, 7 references
[3] doi:10.1038/s41467-025-66354-y [code]
Vulnerability to memory decline in aging revealed by a mega-analysis of structural brain change.
Journal: Nature communications
In common: Alzheimer's / dementia, structural MRI / diffusion, cognitive, 6 references
[4] doi:10.1002/alz.14085 [code]
Educational disparities in brain health and dementia across Latin America and the United States.
Journal: Alzheimer's & dementia : the journal of the Alzheimer's Association
In common: Alzheimer's / dementia, structural MRI / diffusion, 5 references
[5] doi:10.1038/s41467-026-74957-2 [code]
Joint trajectories of brain atrophy, white matter hyperintensities and cognition quantify brain maintenance.
Journal: Nature communications
In common: Alzheimer's / dementia, structural MRI / diffusion, cognitive, 4 references
[6] doi:10.1038/s41598-022-17727-6 [code]
Brain aging differs with cognitive ability regardless of education.
Journal: Scientific reports
In common: structural MRI / diffusion, cognitive, 5 references
[7] doi:10.1186/s13195-024-01528-2
High cognitive reserve attenuates the risk of dementia associated with cardiometabolic diseases.
Journal: Alzheimer's research & therapy
In common: Alzheimer's / dementia, structural MRI / diffusion, 4 references
[8] doi:10.1523/jneurosci.2260-21.2023 [code]
Evidence Accumulation Rate Moderates the Relationship between Enriched Environment Exposure and Age-Related Response Speed Declines.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience
In common: cognitive, 4 references
[9] doi:10.3390/brainsci15060610 [code]
Alterations in Olfactory Cortex Volume in Mild Cognitive Impairment and Mild Alzheimer's Disease Dementia: A Study of Sex-Related Differences.
Journal: Brain sciences
In common: Alzheimer's / dementia, structural MRI / diffusion, 4 references
[10] doi:10.1038/s41467-024-53360-9 [code]
Cognitive reserve against Alzheimer's pathology is linked to brain activity during memory formation.
Journal: Nature communications
In common: Alzheimer's / dementia, cognitive, 4 references

Contribute

The authors of this paper can claim it, correct its record and validate its tracing map, and the maintainers of its code (its owner, or a public member of its organization) correct what it says of their repository; anyone signed in can ask for its removal. Every request goes to OSCR's own machine, which answers it; your account page follows them.

Sign in with ORCID to claim this paper as one of its authors, correct its record or validate its tracing map: when the paper's metadata lists your ORCID iD, you are recognized at once. Maintainers of its code: sign in with GitHub, then claim the repository on your account page.

Request its removal

To ask OSCR to remove this record, the copies of its authors' scripts or its tracing map, use the removal request page: signed in, you say who you are, what to remove and why, then review and confirm the request. Published rules decide every request (how).

Discussion, reproductions, activity

Discussion: code errors and mismatches between the code and the paper about this paper and its code, from readers and its authors, beside the paper and its tracing map.

Reproductions: reports from readers who ran the authors' code and did not get the paper's result, what they ran, with which environment, commit and data.

Activity: what happens around this paper: new versions of its record, its map's validation, discussions and reproductions. It opens with sign-in.