OSCR

Ascl1 Represses Müller Glial and Promotes Rod Photoreceptor Fate Through Repressing Notch Signaling in Late Retinal Progenitor Cells.

Overview

Authors: Canbin Chen1, Zhihan Xing1, Huilin Liang1, Qinghai He1, Shuyi Chen1
  1. State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-Sen University, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science, Guangzhou, China
Journal: Investigative ophthalmology & visual science, volume 67, issue 10, article 41
Dates: received 5 December 2025; accepted 30 July 2026; published online 17 August 2026; in print August 2026
Type: Research article · Language: English
License: CC BY-NC-ND
Identifiers: DOI 10.1167/iovs.67.10.41 · PMID 42606189 · PMCID PMC13492558 · OpenAlex W7203655418
Open access: gold, a free copy (OpenAlex)
Status: data only
Categories: genetics / omics (modality), mouse (organism), cellular / molecular (subfield)
Methods: Statistics, Evoked potentials
Keywords: Ascl1, retinal progenitor cell, Müller glial cell, notch signaling
MeSH: Basic Helix-Loop-Helix Proteins*, Ependymoglial Cells*, Receptors, Notch*, Retinal Rod Photoreceptor Cells*, Stem Cells*, Animals, Cell Differentiation, Cell Proliferation, Electroporation, Mice, Mice, Inbred C57BL, Retina, Signal Transduction (* major topic)
Topic: Retinal Development and Disorders (Molecular Biology, Biochemistry, Genetics and Molecular Biology), according to OpenAlex
Citations: not cited yet (Europe PMC); 53 references in the paper

Abstract

The abstract is not reproduced here: the paper's license (CC BY-NC-ND) does not allow it. Read it in the paper, at the publisher or on Europe PMC.

Code

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Data

Datasets cited

Data availability statement

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Read it in the paper: doi.org/10.1167/iovs.67.10.41.

Versions

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Version 1, 27 September 2026: the first record

Recorded: type, language, journal, volume, issue, pages, dates, 5 authors, 4 keywords, 13 MeSH terms, 53 references.

Cite

This paper

Chen, C., Xing, Z., Liang, H., He, Q., & Chen, S. (2026). Ascl1 Represses Müller Glial and Promotes Rod Photoreceptor Fate Through Repressing Notch Signaling in Late Retinal Progenitor Cells. Investigative ophthalmology & visual science, 67(10), 41. https://doi.org/10.1167/iovs.67.10.41

BibTeX

@article{chen2026ascl1,
author = {Chen, Canbin and Xing, Zhihan and Liang, Huilin and He, Qinghai and Chen, Shuyi},
title = {{Ascl1 Represses Müller Glial and Promotes Rod Photoreceptor Fate Through Repressing Notch Signaling in Late Retinal Progenitor Cells}},
journal = {Investigative ophthalmology \& visual science},
year = {2026},
month = aug,
volume = {67},
number = {10},
pages = {41},
publisher = {Association for Research in Vision and Ophthalmology},
issn = {0146-0404},
doi = {10.1167/iovs.67.10.41},
url = {https://doi.org/10.1167/iovs.67.10.41},
pmid = {42606189},
pmcid = {PMC13492558}
}

RIS

TY - JOUR
AU - Chen, Canbin
AU - Xing, Zhihan
AU - Liang, Huilin
AU - He, Qinghai
AU - Chen, Shuyi
TI - Ascl1 Represses Müller Glial and Promotes Rod Photoreceptor Fate Through Repressing Notch Signaling in Late Retinal Progenitor Cells
T2 - Investigative ophthalmology & visual science
J2 - Invest Ophthalmol Vis Sci
PY - 2026
DA - 2026/08/01
VL - 67
IS - 10
SP - 41
SN - 0146-0404
PB - Association for Research in Vision and Ophthalmology
DO - 10.1167/iovs.67.10.41
UR - https://doi.org/10.1167/iovs.67.10.41
LA - en
ER -

CSL-JSON

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"id": "10.1167/iovs.67.10.41",
"type": "article-journal",
"title": "Ascl1 Represses Müller Glial and Promotes Rod Photoreceptor Fate Through Repressing Notch Signaling in Late Retinal Progenitor Cells",
"container-title": "Investigative ophthalmology & visual science",
"author": [
{
"family": "Chen",
"given": "Canbin"
},
{
"family": "Xing",
"given": "Zhihan"
},
{
"family": "Liang",
"given": "Huilin"
},
{
"family": "He",
"given": "Qinghai"
},
{
"family": "Chen",
"given": "Shuyi"
}
],
"container-title-short": "Invest Ophthalmol Vis Sci",
"volume": "67",
"issue": "10",
"page": "41",
"DOI": "10.1167/iovs.67.10.41",
"PMID": "42606189",
"PMCID": "PMC13492558",
"ISSN": "0146-0404",
"publisher": "Association for Research in Vision and Ophthalmology",
"URL": "https://doi.org/10.1167/iovs.67.10.41",
"language": "en",
"issued": {
"date-parts": [
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2026,
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]
}
}

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