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Integrating multi-omics data revealing LIMK1 as a metastatic biomarker in LUAD patients with brain metastasis.

Overview

Authors: Changqing Yang1, Jianjian Ying2, Cangchang Shi1, Linyue Hai3, Guixin Wang3, Yingxi Li4, Yao Tian2, Jinxian He2, Keyun Zhu2, Jing Feng1
  1. Department of Respiratory and Critical Care Medicine, Tianjin Medical University General Hospital, Tianjin, 300052 China
  2. Department of Thoracic Surgery, The Affiliated LiHuiLi Hospital of Ningbo University, Ningbo, 315040 Zhejiang China
  3. The First Department of Breast Cancer, Key Laboratory of Cancer Prevention and Therapy, Tianjin’s Clinical Research Center for Cancer, Key Laboratory of Breast Cancer Prevention and Therapy, National Clinical Research Center for Cancer, Tianjin Medical University Cancer Institute and Hospital, Tianjin Medical University, Tianjin, 300060 China
  4. Health Science Center, Ningbo University, Ningbo, 315211 Zhejiang China
Institutions: Tianjin Medical University General Hospital (China); Tianjin Medical University (China); Ningbo University (China); Ningbo Medical Center Lihuili Hospital (China); Tianjin Medical University Cancer Institute and Hospital (China)
Journal: Cancer cell international, volume 26, issue 1, article 186
Dates: received 2 September 2025; accepted 15 March 2026; published online 25 March 2026
Type: Research article · Language: English
License: CC BY-NC-ND
Identifiers: DOI 10.1186/s12935-026-04278-3 · PMID 41882657 · PMCID PMC13137581 · OpenAlex W7140322035
Open access: gold, a free copy (OpenAlex)
Status: data only (how the code is found and verified)
Categories: genetics / omics (modality), human (organism), other condition (population), clinical / translational (subfield)
Keywords: lung adenocarcinoma, brain metastasis, tumor heterogeneity, LIMK1, multi-omics
Topic: Lung Cancer Treatments and Mutations (Pulmonary and Respiratory Medicine, Medicine), according to OpenAlex
Funding: Tianjin Key Medical Discipline Construction Project (TJYXZDXK-3-004C); The Medical Science and Technology Project of Zhejiang Province (2024KY284); National Natural Science Foundation of China (82170097); Ningbo Natural Science Foundation (2023J226)
Citations: not cited yet (Europe PMC); 98 references in the paper

Abstract

The abstract is not reproduced here: the paper's license (CC BY-NC-ND) does not allow it. Read it in the paper, at the publisher or on Europe PMC.

Code

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Data

Datasets cited

Data availability statement

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Read it in the paper: doi.org/10.1186/s12935-026-04278-3.

Versions

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Version 1, 30 September 2026: the first record

Recorded: type, language, journal, volume, issue, pages, dates, 10 authors, 5 keywords, 4 funders, 98 references.

Cite

This paper

Yang, C., Ying, J., Shi, C., Hai, L., Wang, G., Li, Y., Tian, Y., He, J., Zhu, K., & Feng, J. (2026). Integrating multi-omics data revealing LIMK1 as a metastatic biomarker in LUAD patients with brain metastasis. Cancer cell international, 26(1), 186. https://doi.org/10.1186/s12935-026-04278-3

BibTeX

@article{yang2026integrating,
author = {Yang, Changqing and Ying, Jianjian and Shi, Cangchang and Hai, Linyue and Wang, Guixin and Li, Yingxi and Tian, Yao and He, Jinxian and Zhu, Keyun and Feng, Jing},
title = {{Integrating multi-omics data revealing LIMK1 as a metastatic biomarker in LUAD patients with brain metastasis}},
journal = {Cancer cell international},
year = {2026},
month = mar,
volume = {26},
number = {1},
pages = {186},
publisher = {BMC},
issn = {1475-2867},
doi = {10.1186/s12935-026-04278-3},
url = {https://doi.org/10.1186/s12935-026-04278-3},
pmid = {41882657},
pmcid = {PMC13137581}
}

RIS

TY - JOUR
AU - Yang, Changqing
AU - Ying, Jianjian
AU - Shi, Cangchang
AU - Hai, Linyue
AU - Wang, Guixin
AU - Li, Yingxi
AU - Tian, Yao
AU - He, Jinxian
AU - Zhu, Keyun
AU - Feng, Jing
TI - Integrating multi-omics data revealing LIMK1 as a metastatic biomarker in LUAD patients with brain metastasis
T2 - Cancer cell international
J2 - Cancer Cell Int
PY - 2026
DA - 2026/03/25
VL - 26
IS - 1
SP - 186
SN - 1475-2867
PB - BMC
DO - 10.1186/s12935-026-04278-3
UR - https://doi.org/10.1186/s12935-026-04278-3
LA - en
ER -

CSL-JSON

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"container-title": "Cancer cell international",
"author": [
{
"family": "Yang",
"given": "Changqing"
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{
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{
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{
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{
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"container-title-short": "Cancer Cell Int",
"volume": "26",
"issue": "1",
"page": "186",
"DOI": "10.1186/s12935-026-04278-3",
"PMID": "41882657",
"PMCID": "PMC13137581",
"ISSN": "1475-2867",
"publisher": "BMC",
"URL": "https://doi.org/10.1186/s12935-026-04278-3",
"language": "en",
"issued": {
"date-parts": [
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]
}
}

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