The IL-17A modulating astrocytic activity was associated with the electroacupuncture-mediated improvement of sensorimotor ability after stroke.
Overview
- South China Research Center for Acupuncture and Moxibustion, Guangzhou University of Chinese Medicine, Guangzhou, GD China
- Dongguan Hospital of Guangzhou University of Chinese Medicine, Dongguan Traditional Chinese Medicine Hospital, Dongguan, GD China
- Health Promotion Center for Primary and Secondary Schools of Guangzhou Municipality, Guangzhou, GD China
Abstract
Both clinical and preclinical evidence showed that electroacupuncture (EA) at Baihui (Governing Vessel 20, GV20) and Dazhui (GV14) could relieve sensorimotor disability after ischemic stroke (IS). However, the mechanism behind this therapeutic remains to be unraveled, and the current findings of its underlying mechanism are mainly focusing on neurons, with little evidence from astrocyte. Astrocyte plays an essential role in IS pathology, and IL-17A as a critical mediator in IS. This study aimed to investigate the relationship between the activity of astrocyte and expression of IL-17A during the regulation of sensorimotor function. The sensorimotor-related behaviors in mice were assessed by using Adhesive removal test and Rotarod test, and the expression/
Supplementary Information: The online version contains supplementary material available at 10.1186/
Reproduced under the paper's license (CC BY), from the paper cited above.
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Data
Datasets cited
- figshare:32835085, at figshare; found in DataCite
- figshare:32835088, at figshare; found in DataCite
- figshare:32835091, at figshare; found in DataCite
- geo:GSE60820, at NCBI GEO; found in the text, “Transcriptomic analysis”
Other data links
- ncbi.nlm.nih.gov/
geo , NCBI; found in the text, “Transcriptomic analysis”
Data availability
The data that support the findings of this study are available from the corresponding authors upon reasonable request.
Reproduced under the paper's license (CC BY), from the paper cited above.
Versions
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Version 1, 27 September 2026: the first record
Recorded: type, language, journal, volume, issue, pages, dates, 8 authors, 5 keywords, 1 funder, 53 references.
Cite
This paper
Yau, Y., Li, Z., Jiang, Z., Luo, J., Wu, Z., Liu, C., Xu, N., & Yao, L. (2026). The IL-17A modulating astrocytic activity was associated with the electroacupuncture-media
BibTeX
@article{yau2026il,
author = {Yau, Yuenming and Li, Zeli and Jiang, Zhiyuan and Luo, Jianyu and Wu, Zhennan and Liu, Chang and Xu, Nenggui and Yao, Lulu},
title = {{The IL-17A modulating astrocytic activity was associated with the electroacupuncture-media
journal = {Chinese medicine},
year = {2026},
month = jun,
volume = {21},
number = {1},
pages = {175},
publisher = {BMC},
issn = {1749-8546},
doi = {10.1186/
url = {https://
pmid = {42374525},
pmcid = {PMC13312517}
}
RIS
TY - JOUR
AU - Yau, Yuenming
AU - Li, Zeli
AU - Jiang, Zhiyuan
AU - Luo, Jianyu
AU - Wu, Zhennan
AU - Liu, Chang
AU - Xu, Nenggui
AU - Yao, Lulu
TI - The IL-17A modulating astrocytic activity was associated with the electroacupuncture-media
T2 - Chinese medicine
J2 - Chin Med
PY - 2026
DA - 2026/
VL - 21
IS - 1
SP - 175
SN - 1749-8546
PB - BMC
DO - 10.1186/
UR - https://
LA - en
ER -
CSL-JSON
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