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Autoregulation-guided intracranial pressure and cerebral perfusion pressure targets in different subtypes and characteristics of traumatic brain injury.

Overview

Authors: Qiang Yuan1,2,3,4,5,6, Hai-Jun Yao1,2,3,4,5,6, Chun Yu1,2,3,4,5,6, Yu Guo1,2,3,4,5,6, Xiang-ru Ye1,2,3,4,5,6, Mei-hua Wang1,2,3,4,5,6, Jie Song1,2,3,4,5,6, Zhen-yang Liu1,2,3,4,5,6, Cai-Hua Xi1,2,3,4,5,6, Lin-hui Chen1,2,3,4,5,6, Zhuo-Ying Du1,2,3,4,5,6, Long Chen1,2,3,4,5,6, Bi-Wu Wu1,2,3,4,5,6, Lei Yang1,2,3,4,5,6, Jin Hu1,2,3,4,5,6, Gang Wu1,2,3,4,5,6
  1. Department of Neurosurgery, Huashan Hospital, Shanghai Medical College, Fudan University,958 Jinguang Road, Shanghai, China
  2. National Center for Neurological Disorders, 958 Jinguang Road, Shanghai, China
  3. Shanghai Key Laboratory of Brain Function and Restoration and Neural Regeneration,958 Jinguang Road, Shanghai, China
  4. Neurosurgical Institute of Fudan University,958 Jinguang Road, Shanghai, China
  5. Shanghai Clinical Medical Center of Neurosurgery,958 Jinguang Road, Shanghai, China
  6. Department of Neurosurgery & Neurocritical Care, Huashan Hospital, Shanghai Medical College, Fudan University,958 Jinguang Road, Shanghai, China
Institutions: Fudan University (China); East China Normal University (China); Huashan Hospital (China)
Journal: Critical care (London, England), volume 30, issue 1, article 287
Dates: received 3 March 2026; accepted 9 April 2026; published online 20 April 2026
Type: Research article · Language: English
License: CC BY-NC-ND
Identifiers: DOI 10.1186/s13054-026-06030-9 · PMID 42010700 · PMCID PMC13227617 · OpenAlex W7154995111
Open access: gold, a free copy (OpenAlex)
Status: code on request
Categories: human (organism), stroke (population), traumatic brain injury (population), clinical / translational (subfield)
Methods: Statistics, Machine learning, Connectivity, Physiology & signal measures
Keywords: Cerebral autoregulation, Pressure reactivity index, Cerebral perfusion pressure, Intracranial pressure, Traumatic brain injury
MeSH: Brain Injuries, Traumatic*, Cerebrovascular Circulation*, Homeostasis*, Intracranial Pressure*, Adult, Aged, Female, Glasgow Outcome Scale, Humans, Male, Middle Aged, Prospective Studies (* major topic)
Topic: Traumatic Brain Injury and Neurovascular Disturbances (Neurology, Medicine), according to OpenAlex
Funding: National Natural Science Foundation of China (82427808, 82471407)
Citations: not cited yet (Europe PMC); 27 references in the paper

Abstract

The abstract is not reproduced here: the paper's license (CC BY-NC-ND) does not allow it. Read it in the paper, at the publisher or on Europe PMC.

Code

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Data

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Code and data availability statement

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  • it says that the data are available on request
  • it says that the code is available on request

Read it in the paper: doi.org/10.1186/s13054-026-06030-9.

Versions

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Version 1, 29 September 2026: the first record

Recorded: type, language, journal, volume, issue, pages, dates, 16 authors, 5 keywords, 12 MeSH terms, 1 funder, 27 references.

Cite

This paper

Yuan, Q., Yao, H.-J., Yu, C., Guo, Y., Ye, X.-r., Wang, M.-h., Song, J., Liu, Z.-y., Xi, C.-H., Chen, L.-h., Du, Z.-Y., Chen, L., Wu, B.-W., Yang, L., Hu, J., & Wu, G. (2026). Autoregulation-guided intracranial pressure and cerebral perfusion pressure targets in different subtypes and characteristics of traumatic brain injury. Critical care (London, England), 30(1), 287. https://doi.org/10.1186/s13054-026-06030-9

BibTeX

@article{yuan2026autoregulation,
author = {Yuan, Qiang and Yao, Hai-Jun and Yu, Chun and Guo, Yu and Ye, Xiang-ru and Wang, Mei-hua and Song, Jie and Liu, Zhen-yang and Xi, Cai-Hua and Chen, Lin-hui and Du, Zhuo-Ying and Chen, Long and Wu, Bi-Wu and Yang, Lei and Hu, Jin and Wu, Gang},
title = {{Autoregulation-guided intracranial pressure and cerebral perfusion pressure targets in different subtypes and characteristics of traumatic brain injury}},
journal = {Critical care (London, England)},
year = {2026},
month = apr,
volume = {30},
number = {1},
pages = {287},
publisher = {BMC},
issn = {1364-8535},
doi = {10.1186/s13054-026-06030-9},
url = {https://doi.org/10.1186/s13054-026-06030-9},
pmid = {42010700},
pmcid = {PMC13227617}
}

RIS

TY - JOUR
AU - Yuan, Qiang
AU - Yao, Hai-Jun
AU - Yu, Chun
AU - Guo, Yu
AU - Ye, Xiang-ru
AU - Wang, Mei-hua
AU - Song, Jie
AU - Liu, Zhen-yang
AU - Xi, Cai-Hua
AU - Chen, Lin-hui
AU - Du, Zhuo-Ying
AU - Chen, Long
AU - Wu, Bi-Wu
AU - Yang, Lei
AU - Hu, Jin
AU - Wu, Gang
TI - Autoregulation-guided intracranial pressure and cerebral perfusion pressure targets in different subtypes and characteristics of traumatic brain injury
T2 - Critical care (London, England)
J2 - Crit Care
PY - 2026
DA - 2026/04/20
VL - 30
IS - 1
SP - 287
SN - 1364-8535
PB - BMC
DO - 10.1186/s13054-026-06030-9
UR - https://doi.org/10.1186/s13054-026-06030-9
LA - en
ER -

CSL-JSON

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