Isolation and characterization of a novel exopolysaccharide from the fermented probiotic <i>Lactiplantibacillus plantarum</i> ZZU-1 and its application for attenuating autism-like behaviors.
Overview
- School of Biological Engineering, Henan University of Technology, Zhengzhou, China
- College of International Education, Henan University of Technology, Zhengzhou, Henan, China
Abstract
Lactic acid bacteria-derived exopolysaccharides (EPS) are natural and safe functional biomolecules whose antioxidant potential is largely dependent on their specific chemical structures. Accumulating evidence suggests that LAB-EPS may exert indirect regulatory effects on oxidative stress-related diseases like autism spectrum disorder via modulating intestinal microecology and relieving oxidative stress in the gut-brain axis. In this study, a novel EPS (EPS-ZZU) was isolated from Lactiplantibacillus plantarum ZZU-1 of traditional fermented Suancai. Structural characterization revealed a 2.141 kDa molecular weight, with mannose, glucose and ribose in a 34.40:26.35:12.24 molar ratio, composed of α-configuration pyranose units. EPS-ZZU exhibited over 90% scavenging rates against the typical free radicals, including hydroxyl radical (⋅OH), 1,1-diphenyl-2-picrylhyd
Reproduced under the paper's license (CC BY), from the paper cited above.
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Data
Data links
- ncbi.nlm.nih.gov/
bioproject/ , NCBI; found in “Data availability statement”1307800
Data availability statement
16s RNA sequencing of strain ZZU-1 was deposited in NCBI under the accession number PV945894, https://
Reproduced under the paper's license (CC BY), from the paper cited above.
Versions
The history of this record: each version stored by the harvester or made by a correction of its authors or of the maintainers of its code, and what changed in its facts. The texts of the paper (its abstract, its availability statements) are not part of it; versions that changed only those are not listed.
Version 2, 28 September 2026
- Funding: added National Natural Science Foundation of China: 32501355, 32500089; Henan University of Technology: 2022BS065; Henan University; Natural Science Foundation of Henan Province
Version 1, 27 September 2026: the first record
Recorded: type, language, journal, volume, pages, dates, 9 authors, 5 keywords, 89 references.
Cite
This paper
Zhao, S., Sun, M., Li, H., Wang, Z., Meng, Z., Xu, Y., Mao, S., Wang, W., & Sun, H. (2026). Isolation and characterization of a novel exopolysaccharide from the fermented probiotic &
BibTeX
@article{zhao2026isolati
author = {Zhao, Shuai and Sun, Mengyi and Li, Hanyan and Wang, Ziyi and Meng, Ziliang and Xu, Yuhan and Mao, Siyi and Wang, Wenchen and Sun, Haowei},
title = {{Isolation and characterization of a novel exopolysaccharide from the fermented probiotic \&
journal = {Frontiers in microbiology},
year = {2026},
month = jul,
volume = {17},
pages = {1806688},
publisher = {Frontiers Media SA},
issn = {1664-302X},
doi = {10.3389/
url = {https://
pmid = {42487714},
pmcid = {PMC13388933}
}
RIS
TY - JOUR
AU - Zhao, Shuai
AU - Sun, Mengyi
AU - Li, Hanyan
AU - Wang, Ziyi
AU - Meng, Ziliang
AU - Xu, Yuhan
AU - Mao, Siyi
AU - Wang, Wenchen
AU - Sun, Haowei
TI - Isolation and characterization of a novel exopolysaccharide from the fermented probiotic &
T2 - Frontiers in microbiology
J2 - Front Microbiol
PY - 2026
DA - 2026/
VL - 17
SP - 1806688
SN - 1664-302X
PB - Frontiers Media SA
DO - 10.3389/
UR - https://
LA - en
ER -
CSL-JSON
{
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"title": "Isolation and characterization of a novel exopolysaccharide from the fermented probiotic &
"container-title": "Frontiers in microbiology",
"author": [
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{
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},
{
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"given": "Ziliang"
},
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"family": "Xu",
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"given": "Siyi"
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{
"family": "Sun",
"given": "Haowei"
}
],
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"volume": "17",
"page": "1806688",
"DOI": "10.3389/
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"URL": "https://
"language": "en",
"issued": {
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}
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