Dichotomy between extracellular signatures of active dendritic chemical synapses and gap junctions.
The 4 matches · 1 of them tie a paragraph to a whole file, not to given lines: a weak match, whose lines are not tinted
- [1] § Methods › Analysis of extracellular field potentials ↔ Code/Matlab/Fig5.m, the whole file · a weak match · score 0.72 · Fourier transform, LFP waveform, cutoff, window, wavelet, bandpass
- [2] § Results › Synchronous inputs: outward transmembrane currents from active dendrites contribute to positive deflection in extracellular potentials associated with gap junctional inputs ↔ Code/Matlab/Fig1.m, lines 42–104 · score 0.62 · 190–300 um, 50–100 um, proximal electrode, 190 um, gap junctions, distal
- [3] § Methods › Analysis of extracellular field potentials ↔ Code/Matlab/Fig1.m, lines 4–41 · score 0.57 · bandpass filtered, cutoff, window, signals, EFP, electrodes
- [4] § Results › Synchronous inputs: contrasting patterns of extracellular signatures associated with active dendritic chemical synapses vs. gap junctions ↔ Code/Matlab/Fig1.m, lines 42–104 · score 0.55 · 190–300 um, 50–100 um, 190 um, gap junctions, distal, traces
Paper
Loaded from Europe PMC by your browser, not stored by OSCR: doi.org · Europe PMC
The paper is loaded when this pane is shown.
The authors' code
MATLAB · 258 lines · 8.6 KB · no license · 3 matches
- % GJLFP, eLife 2026. Richa Sirmaur and Rishikesh Narayanan.
- % Figure 1: waveforms (A-B),boxplots active vs passive (C-D), waveforms across entire neuron (E)
- %% Load dataset and bandpass filter EFP signals
- % loading the EFP data from all 7 arrays, all having 49 electrodes
- dataFiles = {
- 'S1_allLFP_E0-E48.xlsx'
- 'S2_allLFP_E0-E48.xlsx'
- 'S3_allLFP_E0-E48.xlsx'
- 'S4_allLFP_E0-E48.xlsx'
- 'S5_allLFP_E0-E48.xlsx'
- 'S6_allLFP_E0-E48.xlsx'
- 'S7_allLFP_E0-E48.xlsx'
- };
- dataRange = 'A1:AW80000';
- nFiles = numel(dataFiles); % seven
- % FILTER PARAMETERS ----------------
- fs = 40000; % sampling frequency (Hz)
- fc1 = 0.5; % low cutoff (Hz)
- fc2 = 300; % high cutoff (Hz)
- Wn = [fc1 fc2] / (fs/2); % cutoff
- n = 2; % filter order
- [b,a] = butter(n, Wn, 'bandpass');
- % LOAD + FILTER ----------------
- lfpData = [];
- for f = 1:nFiles
- Mat = xlsread(dataFiles{f}, dataRange); % Load dataset
- lfpMat = zeros(size(Mat)); % filtered matrix
- % Filter each electrode trace
- for i = 1:size(Mat,2)
- lfpMat(:,i) = filtfilt(b, a, Mat(:,i)); %forward-backward filtering for no time shift
- end
- lfpData{f} = lfpMat;
- end
- filteredmat = cat(2, lfpData{:}); % concatenating all arrays column-wise (7 arrays each with 49 electrodes) in one matrix
- dt = 1/fs;
- T = (0:size(Mat,1)-1)' * dt;
- % T = time(22001:34001); % specific plotting window
- %% A-B plot example waveforms
- % ####### A:
- basePath = '/chemsyn/synchro/passive/EFP'; % change to '../active/EFP' for active models
- % ===================== PROXIMAL (50–100 µm) =====================
- cd(fullfile(basePath, 'electrode_numbers_50-100'));
- % Load electrode indices
- q = []; % if already loaded and saved call the mat file: load('electrode_numbers.mat'); q = electrode_numbers (n=15)
- % combine proximal electrode data for traces
- data1 = [];
- for k = 1:numel(q)
- data1(:,k) = lfpMat1(:, q(k)); % arrays whose electrode numbers are proximal
- end
- data2 = [];
- for k = 1:numel(q)
- data2(:,k) = lfpMat2(:, q(k)); % arrays whose electrode numbers are proximal
- end
- LFP_prox = [data1, data2]; % Combine
- avg_prox = mean(LFP_prox, 2); % Average across proximal electrodes
- figure; % Plot
- hold on;
- for j = 1:15
- plot(T, LFP_prox(:,j), 'b', 'LineWidth', 1.5); % 'r' for active
- end
- plot(T, avg_prox, 'k', 'LineWidth', 3);
- title('LFPs: 50–100 µm (proximal- passive)');
- xlabel('Time');
- ylabel('LFP (uV)');
- hold off;
- % ===================== distal (190-300 µm) =====================
- cd(fullfile(basePath, 'electrode_numbers_190-300'));
- % Load electrode indices
- q = []; % load('electrode_numbers.mat'); q = electrode_numbers (n=21)
- % combine distal electrode data for traces
- data1 = [];
- for k = 1:numel(q)
- data1(:,k) = lfpMat6(:, q(k)); % arrays whose electrode numbers are picked as distal
- end
- data2 = [];
- for k = 1:numel(q)
- data2(:,k) = lfpMat7(:, q(k)); % arrays whose electrode numbers are picked as distal
- end
- LFP_dist = [data1, data2]; % Combine
- avg_dist = mean(LFP_dist, 2); % Average across distal electrodes
- figure; % Plot
- hold on;
- for j = 1:21
- plot(T, LFP_dist(:,j), 'b', 'LineWidth', 1.5); % 'r' for active
- end
- plot(T, avg_dist, 'k', 'LineWidth', 3);
- title('LFPs: 190-300 µm (distal- passive)'); % change to active
- xlabel('Time (ms)');
- ylabel('LFP (uV)');
- hold off;
- % ####### B:
- % SAME AS 'A' but for gap junctions: /gapj/synchro/passive/EFP, and /gapj/synchro/active/EFP
- %% Boxplot- active vs passive
- nBins = 10;
- activePath = '/sync/active/Negativeamps'; % files have negative amplitudes (negative peaks-baseline) from each electrodes divided into 10 bins based on radial distance from soma
- passivePath = '/sync/passive/Negativeamps';
- colors = [
- 190/255, 30/255, 45/255; % active
- 27/255, 117/255, 187/255 % passive
- ];
- activeColor = colors(1,:);
- passiveColor = colors(2,:);
- activeData = cell(nBins,1);
- passiveData = cell(nBins,1);
- for i = 1:nBins
- fname = sprintf('Bin%d.txt', i);
- activeData{i} = load(fullfile(activePath, fname));
- passiveData{i} = load(fullfile(passivePath, fname));
- end
- meanActive = cellfun(@mean, activeData);
- meanPassive = cellfun(@mean, passiveData);
- x = 1:nBins;
- xActive = x - 0.2;
- xPassive = x + 0.2;
- figure; hold on;
- boxWidth = 0.35;
- % boxplots:
- for i = 1:nBins
- % ---- ACTIVE ----
- boxplot(activeData{i}, 'Positions', xActive(i), ...
- 'Widths', boxWidth, ...
- 'Colors', activeColor, ...
- 'Symbol', '');
- h = findobj(gca,'Tag','Box');
- patch(get(h(1),'XData'), get(h(1),'YData'), ...
- activeColor, 'FaceAlpha', 0.2, ...
- 'EdgeColor', activeColor, 'LineWidth', 2);
- % ---- PASSIVE ----
- boxplot(passiveData{i}, 'Positions', xPassive(i), ...
- 'Widths', boxWidth, ...
- 'Colors', passiveColor, ...
- 'Symbol', '');
- h = findobj(gca,'Tag','Box');
- patch(get(h(1),'XData'), get(h(1),'YData'), ...
- passiveColor, 'FaceAlpha', 0.2, ...
- 'EdgeColor', passiveColor, 'LineWidth', 2);
- end
- % set(findobj(gca,'Type','line'),'LineStyle','-');
- xticks(linspace(0,250,6));
- xticklabels(string(linspace(0,250,6)));
- xlabel('Radial distance (µm)');
- ylabel('LFP');
- title('Active vs Passive LFP');
- set(gca, 'YScale', 'log');
- box off;
- hold off;
- % Inset: line plot:
- fogure; hold on;
- plot(x, meanActive, '-', ...
- 'Color', activeColor, ...
- 'LineWidth', 2);
- plot(x, meanPassive, '-', ...
- 'Color', passiveColor, ...
- 'LineWidth', 2);
- set(gca, 'XLim', [0 250]);
- box off;
- hold off;
- %% waveforms spanning the entire neuron (E)
- % basal waveforms from above mentioned filtered mat, load and filter EFP recorded from apical dendritic side
- dataFiles_apical = {
- 'S1_allLFP_E0-E48.xlsx'
- 'S2_allLFP_E0-E48.xlsx'
- 'S3_allLFP_E0-E48.xlsx'
- 'S4_allLFP_E0-E48.xlsx'
- 'S5_allLFP_E0-E48.xlsx'
- 'S6_allLFP_E0-E48.xlsx'
- 'S7_allLFP_E0-E48.xlsx'
- };
- dataRange = 'A1:AW80000';
- nFiles = numel(dataFiles); % seven
- lfpData_apical = [];
- for f = 1:nFiles
- Mat_apical = xlsread(dataFiles_apical{f}, dataRange); % Load dataset
- lfpMat = zeros(size(Mat_apical)); % filtered matrix
- % Filter each electrode trace
- for i = 1:size(Mat_apical,2)
- lfpMat(:,i) = filtfilt(b, a, Mat_apical(:,i)); %forward-backward filtering for no time shift
- end
- lfpData_apical{f} = lfpMat_apical;
- end
- filteredmat_apical = cat(2, lfpData_apical{:}); % concatenating all arrays column-wise (7 arrays each with 49 electrodes) in one matrix
- T = T(4001:48001,1);
- % basal:
- waveform_1 = FilteredMat2(4001:48001,32); waveforms(:,1) = waveform_1;
- waveform_2 = FilteredMat3(4001:48001,32); waveforms(:,2) = waveform_2;
- waveform_3 = FilteredMat3(4001:48001,39); waveforms(:,3) = waveform_3;
- waveform_4 = FilteredMat1(4001:48001,34); waveforms(:,4) = waveform_4;
- waveform_5 = FilteredMat3(4001:48001,45); waveforms(:,5) = waveform_5;
- waveform_6 = FilteredMat1(4001:48001,36); waveforms(:,6) = waveform_6;
- waveform_7 = FilteredMat6(4001:48001,47); waveforms(:,7) = waveform_7;
- % waveform_8 = FilteredMat2(4001:48001,4); waveforms(:,8) = waveform_8;
- % waveform_9 = FilteredMat3(4001:48001,1); waveforms(:,9) = waveform_9;
- % waveform_10 = FilteredMat6(4001:48001,7); waveforms(:,10) = waveform_10;
- % apical
- Ap_waveforms_A = zeros(length(T), num_Ap_waveforms);
- Ap_waveform_11 = filteredmat_apical2(4001:48001,32); Ap_waveforms_A(:,1) = Ap_waveform_11;
- Ap_waveform_12 = filteredmat_apical3(4001:48001,32); Ap_waveforms_A(:,2) = Ap_waveform_12;
- Ap_waveform_13 = filteredmat_apical3(4001:48001,39); Ap_waveforms_A(:,3) = Ap_waveform_13;
- Ap_waveform_14 = filteredmat_apical1(4001:48001,34); Ap_waveforms_A(:,4) = Ap_waveform_14;
- Ap_waveform_15 = filteredmat_apical3(4001:48001,45); Ap_waveforms_A(:,5) = Ap_waveform_15;
- Ap_waveform_16 = filteredmat_apical1(4001:48001,36); Ap_waveforms_A(:,6) = Ap_waveform_16;
- Ap_waveform_17 = filteredmat_apical6(4001:48001,47); Ap_waveforms_A(:,7) = Ap_waveform_17;
- % Ap_waveform_18 = filteredmat_apical2(4001:48001,4); Ap_waveforms_A(:,8) = Ap_waveform_18;
- % Ap_waveform_19 = filteredmat_apical3(4001:48001,1); Ap_waveforms_A(:,9) = Ap_waveform_19;
- % Ap_waveform_20 = filteredmat_apical6(4001:48001,7); Ap_waveforms_A(:,10) = Ap_waveform_20;
- figure;
- num_waveforms = 7; % Number of waveforms in each set (taking 7 for plotting)
- total_waveforms = 14; % Total number
- for i = 1:total_waveforms
- subplot(total_waveforms, 1, i);
- if i <= num_waveforms
- % Plot the first 7 waveforms from waveforms (basal)
- plot(T, waveforms(:,i));
- else
- % Plot the next 7 waveforms from Ap_waveforms (apical)
- plot(T, Ap_waveforms_(:,i - num_waveforms));
- end
- xlabel('Time');
- ylabel('Amplitude');
- % title(['Waveform ', num2str(i)]); % Uncomment this line if you want to add titles
- % xlim([100 1200]);
- % ylim([-100 100]);
- box off;
- end
- % do the same for gap junctional EFPs for right side waveforms.
Fig1.m, no license · at the source
Overview
Abstract
Local field potentials (LFPs) are compound signals that represent the dynamic flow of information across the brain, which have been historically associated with chemical synaptic inputs. How do gap junctional inputs onto active compartments shape LFPs? We developed a methodology to record extracellular potentials associated with different patterns of gap junctional inputs onto conductance-based models. We found that synchronous inputs through chemical synapses yielded a negative deflection in proximal extracellular electrodes whereas those onto gap junctions manifested a positive deflection. Importantly, we observed extracellular dipoles only when inputs arrived through chemical synapses but not with gap junctions. Remarkably, hyperpolarization-activa
Reproduced under the paper's license (CC BY), from the paper cited above.
Repositories
Its files are read in the Code ↔ Paper reader above, with 4 matches between paragraphs and lines of code.
Zenodo 21312084
Availability: 1 check, the latest on 27 September 2026: the link answers (HTTP 200)
- 27 September 2026: the link answers (HTTP 200)
58 files
- Code/
Chem/ , NEURON, 642 lines1a_ChemSync_Act.hoc - Code/
Chem/ , Python, 449 lines1a_LFPy_S1toS7.py - Code/
Chem/ , NEURON, 654 lines1b_ChemRand_Act.hoc - Code/
Chem/ , Python, 449 lines1b_LFPy_S1toS7.py - Code/
Chem/ , NEURON, 600 lines1c_ChemPattern_Act.hoc - Code/
Chem/ , Python, 449 lines1c_LFPy_S1toS7.py - Code/
Chem/ , NEURON, 89 linesMod Files/ cad.mod - Code/
Chem/ , NEURON, 111 linesMod Files/ cal.mod - Code/
Chem/ , NEURON, 143 linesMod Files/ can2.mod - Code/
Chem/ , NEURON, 88 linesMod Files/ car.mod - Code/
Chem/ , NEURON, 128 linesMod Files/ cat.mod - Code/
Chem/ , NEURON, 126 linesMod Files/ ghkampa.mod - Code/
Chem/ , NEURON, 145 linesMod Files/ ghknmda.mod - Code/
Chem/ , NEURON, 91 linesMod Files/ h.mod - Code/
Chem/ , NEURON, 107 linesMod Files/ kadist.mod - Code/
Chem/ , NEURON, 121 linesMod Files/ kaprox.mod - Code/
Chem/ , NEURON, 91 linesMod Files/ kdrca1.mod - Code/
Chem/ , NEURON, 80 linesMod Files/ km.mod - Code/
Chem/ , NEURON, 35 linesMod Files/ minmax.mod - Code/
Chem/ , NEURON, 132 linesMod Files/ na3.mod - Code/
Chem/ , NEURON, 132 linesMod Files/ na3s.mod - Code/
Chem/ , NEURON, 99 linesMod Files/ nax.mod - Code/
Chem/ , NEURON, 67 linesMod Files/ skkin.mod - Code/
Chem/ , NEURON, 22 linesMod Files/ vmax.mod - Code/
Chem/ , NEURON, 5,789 linesn123.hoc - Code/
Gap/ , NEURON, 612 lines2a_GapSync_Act.hoc - Code/
Gap/ , Python, 449 lines2a_LFPy_S1toS7.py - Code/
Gap/ , NEURON, 617 lines2b_GapRand_Act.hoc - Code/
Gap/ , Python, 449 lines2b_LFPy_S1toS7.py - Code/
Gap/ , NEURON, 647 lines2c_GapPattern_Act.hoc - Code/
Gap/ , Python, 449 lines2c_LFPy_S1toS7.py - Code/
Gap/ , NEURON, 89 linesMod Files/ cad.mod - Code/
Gap/ , NEURON, 111 linesMod Files/ cal.mod - Code/
Gap/ , NEURON, 143 linesMod Files/ can2.mod - Code/
Gap/ , NEURON, 88 linesMod Files/ car.mod - Code/
Gap/ , NEURON, 128 linesMod Files/ cat.mod - Code/
Gap/ , NEURON, 126 linesMod Files/ ghkampa.mod - Code/
Gap/ , NEURON, 145 linesMod Files/ ghknmda.mod - Code/
Gap/ , NEURON, 91 linesMod Files/ h.mod - Code/
Gap/ , NEURON, 107 linesMod Files/ kadist.mod - Code/
Gap/ , NEURON, 121 linesMod Files/ kaprox.mod - Code/
Gap/ , NEURON, 91 linesMod Files/ kdrca1.mod - Code/
Gap/ , NEURON, 80 linesMod Files/ km.mod - Code/
Gap/ , NEURON, 35 linesMod Files/ minmax.mod - Code/
Gap/ , NEURON, 132 linesMod Files/ na3.mod - Code/
Gap/ , NEURON, 132 linesMod Files/ na3s.mod - Code/
Gap/ , NEURON, 99 linesMod Files/ nax.mod - Code/
Gap/ , NEURON, 67 linesMod Files/ skkin.mod - Code/
Gap/ , NEURON, 22 linesMod Files/ vmax.mod - Code/
Gap/ , NEURON, 5,789 linesn123.hoc - Code/
Matlab/ , MATLAB, 258 linesFig1.m - Code/
Matlab/ , MATLAB, 276 linesFig2.m - Code/
Matlab/ , MATLAB, 67 linesFig3.m - Code/
Matlab/ , MATLAB, 93 linesFig4.m - Code/
Matlab/ , MATLAB, 96 linesFig5.m - Code/
Matlab/ , MATLAB, 148 linesFig6.m - Code/
Matlab/ , MATLAB, 225 linesFig7.m - Code/
Matlab/ , MATLAB, 250 linesFig8.m
supp:PMC13423354/elife-103046-code1.zip
Availability: 1 check, the latest on 27 September 2026: the link answers (HTTP 200)
- 27 September 2026: the link answers (HTTP 200)
96 files
- Code/
Chem/ , NEURON, 642 lines1a_ChemSync_Act.hoc - Code/
Chem/ , Python, 449 lines1a_LFPy_S1toS7.py - Code/
Chem/ , NEURON, 654 lines1b_ChemRand_Act.hoc - Code/
Chem/ , Python, 449 lines1b_LFPy_S1toS7.py - Code/
Chem/ , NEURON, 600 lines1c_ChemPattern_Act.hoc - Code/
Chem/ , Python, 449 lines1c_LFPy_S1toS7.py - Code/
Chem/ , C, 575 linesMod Files/ arm64/ cad.c - Code/
Chem/ , C, 738 linesMod Files/ arm64/ cal.c - Code/
Chem/ , C, 858 linesMod Files/ arm64/ can2.c - Code/
Chem/ , C, 761 linesMod Files/ arm64/ car.c - Code/
Chem/ , C, 810 linesMod Files/ arm64/ cat.c - Code/
Chem/ , C, 773 linesMod Files/ arm64/ ghkampa.c - Code/
Chem/ , C, 895 linesMod Files/ arm64/ ghknmda.c - Code/
Chem/ , C, 593 linesMod Files/ arm64/ h.c - Code/
Chem/ , C, 728 linesMod Files/ arm64/ kadist.c - Code/
Chem/ , C, 742 linesMod Files/ arm64/ kaprox.c - Code/
Chem/ , C, 617 linesMod Files/ arm64/ kdrca1.c - Code/
Chem/ , C, 666 linesMod Files/ arm64/ km.c - Code/
Chem/ , C, 348 linesMod Files/ arm64/ minmax.c - Code/
Chem/ , C++, 73 linesMod Files/ arm64/ mod_func.cpp - Code/
Chem/ , C, 826 linesMod Files/ arm64/ na3.c - Code/
Chem/ , C, 831 linesMod Files/ arm64/ na3s.c - Code/
Chem/ , C, 674 linesMod Files/ arm64/ nax.c - Code/
Chem/ , C, 868 linesMod Files/ arm64/ skkin.c - Code/
Chem/ , C, 330 linesMod Files/ arm64/ vmax.c - Code/
Chem/ , NEURON, 89 linesMod Files/ cad.mod - Code/
Chem/ , NEURON, 111 linesMod Files/ cal.mod - Code/
Chem/ , NEURON, 143 linesMod Files/ can2.mod - Code/
Chem/ , NEURON, 88 linesMod Files/ car.mod - Code/
Chem/ , NEURON, 128 linesMod Files/ cat.mod - Code/
Chem/ , NEURON, 126 linesMod Files/ ghkampa.mod - Code/
Chem/ , NEURON, 145 linesMod Files/ ghknmda.mod - Code/
Chem/ , NEURON, 91 linesMod Files/ h.mod - Code/
Chem/ , NEURON, 107 linesMod Files/ kadist.mod - Code/
Chem/ , NEURON, 121 linesMod Files/ kaprox.mod - Code/
Chem/ , NEURON, 91 linesMod Files/ kdrca1.mod - Code/
Chem/ , NEURON, 80 linesMod Files/ km.mod - Code/
Chem/ , NEURON, 35 linesMod Files/ minmax.mod - Code/
Chem/ , NEURON, 132 linesMod Files/ na3.mod - Code/
Chem/ , NEURON, 132 linesMod Files/ na3s.mod - Code/
Chem/ , NEURON, 99 linesMod Files/ nax.mod - Code/
Chem/ , NEURON, 67 linesMod Files/ skkin.mod - Code/
Chem/ , NEURON, 22 linesMod Files/ vmax.mod - Code/
Chem/ , NEURON, 5,789 linesn123.hoc - Code/
Gap/ , NEURON, 612 lines2a_GapSync_Act.hoc - Code/
Gap/ , Python, 449 lines2a_LFPy_S1toS7.py - Code/
Gap/ , NEURON, 617 lines2b_GapRand_Act.hoc - Code/
Gap/ , Python, 449 lines2b_LFPy_S1toS7.py - Code/
Gap/ , NEURON, 647 lines2c_GapPattern_Act.hoc - Code/
Gap/ , Python, 449 lines2c_LFPy_S1toS7.py - Code/
Gap/ , C, 575 linesMod Files/ arm64/ cad.c - Code/
Gap/ , C, 738 linesMod Files/ arm64/ cal.c - Code/
Gap/ , C, 858 linesMod Files/ arm64/ can2.c - Code/
Gap/ , C, 761 linesMod Files/ arm64/ car.c - Code/
Gap/ , C, 810 linesMod Files/ arm64/ cat.c - Code/
Gap/ , C, 773 linesMod Files/ arm64/ ghkampa.c - Code/
Gap/ , C, 895 linesMod Files/ arm64/ ghknmda.c - Code/
Gap/ , C, 593 linesMod Files/ arm64/ h.c - Code/
Gap/ , C, 728 linesMod Files/ arm64/ kadist.c - Code/
Gap/ , C, 742 linesMod Files/ arm64/ kaprox.c - Code/
Gap/ , C, 617 linesMod Files/ arm64/ kdrca1.c - Code/
Gap/ , C, 666 linesMod Files/ arm64/ km.c - Code/
Gap/ , C, 348 linesMod Files/ arm64/ minmax.c - Code/
Gap/ , C++, 73 linesMod Files/ arm64/ mod_func.cpp - Code/
Gap/ , C, 826 linesMod Files/ arm64/ na3.c - Code/
Gap/ , C, 831 linesMod Files/ arm64/ na3s.c - Code/
Gap/ , C, 674 linesMod Files/ arm64/ nax.c - Code/
Gap/ , C, 868 linesMod Files/ arm64/ skkin.c - Code/
Gap/ , C, 330 linesMod Files/ arm64/ vmax.c - Code/
Gap/ , NEURON, 89 linesMod Files/ cad.mod - Code/
Gap/ , NEURON, 111 linesMod Files/ cal.mod - Code/
Gap/ , NEURON, 143 linesMod Files/ can2.mod - Code/
Gap/ , NEURON, 88 linesMod Files/ car.mod - Code/
Gap/ , NEURON, 128 linesMod Files/ cat.mod - Code/
Gap/ , NEURON, 126 linesMod Files/ ghkampa.mod - Code/
Gap/ , NEURON, 145 linesMod Files/ ghknmda.mod - Code/
Gap/ , NEURON, 91 linesMod Files/ h.mod - Code/
Gap/ , NEURON, 107 linesMod Files/ kadist.mod - Code/
Gap/ , NEURON, 121 linesMod Files/ kaprox.mod - Code/
Gap/ , NEURON, 91 linesMod Files/ kdrca1.mod - Code/
Gap/ , NEURON, 80 linesMod Files/ km.mod - Code/
Gap/ , NEURON, 35 linesMod Files/ minmax.mod - Code/
Gap/ , NEURON, 132 linesMod Files/ na3.mod - Code/
Gap/ , NEURON, 132 linesMod Files/ na3s.mod - Code/
Gap/ , NEURON, 99 linesMod Files/ nax.mod - Code/
Gap/ , NEURON, 67 linesMod Files/ skkin.mod - Code/
Gap/ , NEURON, 22 linesMod Files/ vmax.mod - Code/
Gap/ , NEURON, 5,789 linesn123.hoc - Code/
Matlab/ , MATLAB, 258 lines, 3 matchesFig1.m - Code/
Matlab/ , MATLAB, 276 linesFig2.m - Code/
Matlab/ , MATLAB, 67 linesFig3.m - Code/
Matlab/ , MATLAB, 93 linesFig4.m - Code/
Matlab/ , MATLAB, 96 lines, 1 matchFig5.m - Code/
Matlab/ , MATLAB, 148 linesFig6.m - Code/
Matlab/ , MATLAB, 225 linesFig7.m - Code/
Matlab/ , MATLAB, 250 linesFig8.m
The paper's code and data availability statement is in the Data section.
Tracing map
Proposed by the machine: these links were found in the paper and verified at the source, without human review. The map will receive a Zenodo DOI once one of the paper's authors has validated it with their ORCID.
What the map holds:
- 2 repositories of the authors' code, each at its verified commit, with its license and how the link was found in the paper;
- 154 scripts, each with its path and the digest of its content;
- 4 matches between paragraphs of the paper and lines of the code (method lexical-v1);
- neither the text of the paper nor the code itself.
Its JSON (tracing-map.json) is deposited on Zenodo with its DOI once the map is validated.
Data
No dataset and no data link were found in the paper.
Data availability
The current manuscript is a computational study, so no data have been generated for this manuscript. All source codes for simulation and analyses are publicly available at https://
The following dataset was generated:
Sirmaur R, Narayanan R. 2026. Codes. Zenodo.
Reproduced under the paper's license (CC BY), from the paper cited above.
Versions
The history of this record: each version stored by the harvester or made by a correction of its authors or of the maintainers of its code, and what changed in its facts. The texts of the paper (its abstract, its availability statements) are not part of it; versions that changed only those are not listed.
Version 1, 27 September 2026: the first record
Recorded: type, language, journal, volume, pages, dates, 2 authors, 1 keyword, 6 MeSH terms, 2 funders, 127 references, 7 RRIDs.
Cite
This paper
Sirmaur, R., & Narayanan, R. (2026). Dichotomy between extracellular signatures of active dendritic chemical synapses and gap junctions. eLife, 14, RP103046. https://
BibTeX
@article{sirmaur2026dich
author = {Sirmaur, Richa and Narayanan, Rishikesh},
title = {{Dichotomy between extracellular signatures of active dendritic chemical synapses and gap junctions}},
journal = {eLife},
year = {2026},
month = jul,
volume = {14},
pages = {RP103046},
publisher = {eLife Sciences Publications, Ltd},
issn = {2050-084X},
doi = {10.7554/
url = {https://
pmid = {42528398},
pmcid = {PMC13423354}
}
RIS
TY - JOUR
AU - Sirmaur, Richa
AU - Narayanan, Rishikesh
TI - Dichotomy between extracellular signatures of active dendritic chemical synapses and gap junctions
T2 - eLife
J2 - eLife
PY - 2026
DA - 2026/
VL - 14
SP - RP103046
SN - 2050-084X
PB - eLife Sciences Publications, Ltd
DO - 10.7554/
UR - https://
LA - en
ER -
CSL-JSON
{
"id": "10.7554/
"type": "article-journal",
"title": "Dichotomy between extracellular signatures of active dendritic chemical synapses and gap junctions",
"container-title": "eLife",
"author": [
{
"family": "Sirmaur",
"given": "Richa"
},
{
"family": "Narayanan",
"given": "Rishikesh"
}
],
"container-title-short":
"volume": "14",
"page": "RP103046",
"DOI": "10.7554/
"PMID": "42528398",
"PMCID": "PMC13423354",
"ISSN": "2050-084X",
"publisher": "eLife Sciences Publications, Ltd",
"URL": "https://
"language": "en",
"issued": {
"date-parts": [
[
2026,
7,
30
]
]
}
}
The tracing map gets a citation of its own once an author has validated it and it has a DOI.
Similar papers
The papers with a page that share the most with this one: the tools found in their code, their categories, datasets, cited references and authors, the rarest counting most.
- [1] doi:10.1038/s41398-026-04018-1
- Loss of connexin 36 elicits abnormalities in thalamocortical network activity relevant to neuropsychiatric disorders.Journal: Translational psychiatryIn common: 8 references
- [2] doi:10.1016/j.celrep.2026.117793 [code]
- Clustered inputs engage dendritic nonlinearities and calcium signaling to support efficient place-field formation in CA1 pyramidal neurons.Journal: Cell reportsIn common: NEURON, Matplotlib, NumPy, cellular / molecular, 5 references
- [3] doi:10.1371/journal.pcbi.1014283 [code]
- Spatial richness of neural magnetic fields.Journal: PLoS computational biologyIn common: LFPy, NEURON, Matplotlib, 1 other tool, 3 references
- [4] doi:10.7554/elife.108352 [code]
- Analysis of dendritic input currents during place field dynamics.Journal: eLifeIn common: NEURON, Matplotlib, NumPy, 4 references
- [5] doi:10.1002/advs.202519893 [code]
- NeuroSuite for Long-Term Functional and Structural Studies of Air-Liquid Interface Cerebral Organoids.Journal: Advanced science (Weinheim, Baden-Wurttemberg, Germany)In common: Wavelet Toolbox, Signal Processing Toolbox, Statistics and Machine Learning Toolbox, 2 other tools, extracellular electrophysiology (units, LFP), 2 references
- [6] doi:10.1038/s41586-026-10331-y [code]
- Active dissociation of intracortical spiking and high gamma activity.Journal: NatureIn common: Matplotlib, NumPy, extracellular electrophysiology (units, LFP), 5 references
- [7] doi:10.1162/imag.a.1229 [code]
- 40 Hz audiovisual stimulation improves sustained attention and related brain oscillations.Journal: Imaging neuroscience (Cambridge, Mass.)In common: Wavelet Toolbox, Signal Processing Toolbox, Statistics and Machine Learning Toolbox, 2 other tools, 2 references
- [8] doi:10.1016/j.celrep.2026.117646 [code]
- Medial entorhinal-hippocampal desynchronization parallels the emergence of memory impairment in a mouse model of Alzheimer's disease pathology.Journal: Cell reportsIn common: Signal Processing Toolbox, Statistics and Machine Learning Toolbox, Matplotlib, 1 other tool, 3 references
- [9] doi:10.1371/journal.pcbi.1014304 [code]
- Linking reduced prefrontal microcircuit inhibition in schizophrenia to EEG biomarkers in silico.Journal: PLoS computational biologyIn common: LFPy, NEURON, Matplotlib, 1 other tool, 1 reference
- [10] doi:10.7554/elife.100642 [code]
- Disrupted hippocampal theta-gamma coupling and spike-field coherence following experimental traumatic brain injury.Journal: eLifeIn common: Wavelet Toolbox, Signal Processing Toolbox, 3 references
Contribute
The authors of this paper can claim it, correct its record and validate its tracing map, and the maintainers of its code (its owner, or a public member of its organization) correct what it says of their repository; anyone signed in can ask for its removal. Every request goes to OSCR's own machine, which answers it; your account page follows them.
Sign in with ORCID to claim this paper as one of its authors, correct its record or validate its tracing map: when the paper's metadata lists your ORCID iD, you are recognized at once. Maintainers of its code: sign in with GitHub, then claim the repository on your account page.
Claim this paper
Correct its record
Say what each link of this record is, remove the ones that are not the paper's, add the ones that are missing. The correction becomes a new version of the record, in its Versions section.
Validate its tracing map
You validate the map as this page shows it: 2 repositories of the authors' code, each at its verified commit and with its license, 154 scripts, and 4 matches between paragraphs and code (see the Code and Map sections). It then receives a DOI on Zenodo, with you (your ORCID iD) and OSCR as its creators; the code itself is not deposited.
The map's fingerprint: sha256:e3ba8b9595e88248…
Add the badge to its README
The badge links the code to this page. Copy one of these into the README of the paper's code: only you decide where it goes, and nothing is changed for you.
Markdown
[.
Discussion, reproductions, activity
Discussion: questions and error reports about this paper and its code, from signed-in readers and its authors. It opens with sign-in.
Reproductions: reports from readers who ran the authors' code: what they reproduced, with which environment, commit and data. It opens with sign-in.
Activity: what happens around this paper: new versions of its record, its map's validation, discussions and reproductions. It opens with sign-in.
