Visual information is broadcast among cortical areas in discrete channels.
The 4 matches
- [1] § Results › Functional connectivity is stable across stimuli ↔ NSC_compare.m, lines 274 to 342 · score 0.62 · linear predictor, error bars, naturalistic video, Variance explained, model, grating · Report a mismatch
- [2] § Materials and methods › Decompose neural activity ↔ FR_pupilAna.m, lines 37 to 161 · score 0.58 · pupil dynamics, ordinary regression, prediction, video, model, variance · Report a mismatch
- [3] § Materials and methods › Decompose neural activity ↔ FR_pupilAna.m, lines 37 to 161 · score 0.58 · pupil dynamics, residual population, subtracting, regression, model, stimulus · Report a mismatch
- [4] § Results › Tuning similarity is a major factor in the V1-HVA functional network ↔ NSCmean_vsDist.m, lines 354 to 452 · score 0.55 · error bar, neuron distance, signal correlation, FR, V1 · Report a mismatch
Paper
Loaded from Europe PMC by your browser; OSCR does not store it: doi.org · Europe PMC
The paper is loaded when this pane is shown.
The authors' code
MATLAB · 263 lines · 11 KB · GPL-3.0 · 2 matches
- load('pooldata_SinGrat.mat', 'pooldata','name1','areaID')
- load('pooldata_pupiltrack.mat')
- Dir = [0, 135, 270, 45, 180, 315, 90, 225];
- [DirSort, DirInd] = sort(Dir);
- stimPara = ...
- [8 0.16;
- 2 0.02;
- 8 0.02;
- 1 0.02;
- 1 0.16;
- 2 0.16;
- 8 0.04;
- 2 0.04;
- 1 0.04];
- stimflag = [repmat(Dir',9,1)/360*2*pi, reshape(repmat(stimPara(:,1),1,8)',[],1),...
- reshape(repmat(stimPara(:,2),1,8)',[],1)];
- [stimsort, stimInd] = sortrows(stimPara, [1 2]);
- TmFreq = [1,2,8];
- SpFreq = [0.02, 0.04, 0.16];
- % TmFreq = stimsort(:,1);
- % SpFreq = stimsort(:,2);
- Twindow = [0 2 4 6 8 10 12 14 16]; % s
- delay = 0;
- DirSortVect = [0 1; -sqrt(2)/2 sqrt(2)/2; -1 0;-sqrt(2)/2 -sqrt(2)/2; 0 -1;sqrt(2)/2 -sqrt(2)/2; 1 0;sqrt(2)/2 sqrt(2)/2];
- %%
- Npc = [];
- for k1 = 1:length(poolpupildata)
- if ~isempty(poolpupildata(k1).pupildata)
- pupildata = poolpupildata(k1).pupildata;
- if isfield(pupildata, 'pupilsync')
- Npc(k1,1) = pupildata.video_PCdim;
- Npc(k1,2) = pupildata.video_PCvar;
- end
- end
- end
- %%
- binWidth = 100;
- smoothSD = 2;
- popResp_var = [];
- for k1 = 1:length(poolpupildata)
- if ~isempty(poolpupildata(k1).pupildata)
- pupildata = poolpupildata(k1).pupildata;
- if isfield(pupildata, 'pupilsync')
- pupilsync = pupildata.pupilsync;
- sync2p = table2array(poolpupildata(k1).sync2p);
- l0 = find(pupilsync(:,3)==1,1);
- l1 = find(pupilsync(:,3)==1,1,'last');
- pupildyn = [pupildata.eyearea(l0:l1)',pupildata.eyecenter(l0:l1,:),pupildata.videoscore];
- pupildyn(pupildyn(:,1)==0,1:3) = nan;
- pupilPC(k1,1:2) = [pupildata.video_PCdim, pupildata.video_PCvar];
- pupildyn_t = pupilsync(l0:l1,1:2);
- pupildyn_t = bsxfun(@minus, pupildyn_t, pupildyn_t(1,:))+1;
- pupildyn_match2p = [];
- for j = 1:size(pupildyn,2)
- tmp = interp1(pupildyn_t(:,1)/pupildyn_t(end,1), pupildyn(:,j), sync2p(:,1)/sync2p(end,1));
- pupildyn_match2p = cat(2, pupildyn_match2p, tmp);
- end
- imgPara = pooldata(k1,1).imgPara;
- % pupil dynamics bined per direction (2 sec window)
- pupildyn_bin = [];
- for i = 1:imgPara.stimrep
- for j = 1:imgPara.stim_type
- tmp = pupildyn_match2p(sync2p(:,3)==i & sync2p(:,5)==j,:);
- tmp1 = imresize(tmp, [8 size(tmp,2)]);
- pupildyn_bin = cat(1, pupildyn_bin, tmp1);
- end
- end
- X_pupildyn = pupildyn_bin;
- X_stim = repmat(stimflag, imgPara.stimrep, 1);
- for k2 = 1:4
- if ~isempty(pooldata(k1,k2).spiketrain) && length(pooldata(k1,k2).goodcell) > 5
- goodcell = pooldata(k1,k2).goodcell;
- spiketrain = pooldata(k1,k2).spiketrain(goodcell);
- num(k1,k2) = length(goodcell);
- spikecountAve = []; h = []; spikecountraw1 = [];
- spikecountraw2 = []; snr = [];
- for n = 1:length(goodcell)
- tmphist = [];
- stvec = [];
- for i = 1:imgPara.stimrep
- st1 = [];
- for j = 1:imgPara.stim_type
- st = spiketrain(n).st{i,j}*imgPara.dt;
- st(st<0) = [];
- st(st>imgPara.stim_time) = [];
- st1 = [st1, st+imgPara.stim_time*(j-1)];
- tmphist1 = histcounts(st, Twindow);
- tmphist = cat(1, tmphist, tmphist1');
- end
- stvec = vectCat(stvec, st1');
- end
- [rate , rateT] = myPSTH(stvec*1000, [0, imgPara.stim_time*imgPara.stim_type]*1000, binWidth, smoothSD);
- spikecountraw1(n,:) = tmphist;
- spikecountAve(n,:) = rate;
- end
- % total variance of population response
- Y = spikecountraw1';
- Y = bsxfun(@minus, Y, mean(Y,1));
- Y_totvar = var(Y(:));
- % variance explained by stimulus induced response
- Ym = mean(reshape(Y, 72,imgPara.stimrep,size(Y,2)), 2);
- Ym_var = var(Ym(:));
- Y_stimexp = Ym_var/Y_totvar;
- % residual population response after subtracting stimulus
- % induced portion (estimated by trial averaged response)
- Y = bsxfun(@minus, reshape(Y, 72,imgPara.stimrep,size(Y,2)), Ym);
- Y = reshape(Y,[],size(Y,3));
- Y_resvar = var(Y(:));
- % ordinary regression variance explained by pupil dynamics
- X = X_pupildyn;
- X(isnan(X)) = 0;
- % Bols = inv(X'*X)*X'*Y;
- % Yhat2 = X*Bols;
- % e = mean((Yhat2-Y).^2);
- % Y_pupildynexp_OLS = 1-mean(e./var(Y));
- e = []; d = [];
- for k = 1:size(X,2)
- [Br, Bols, e(k), d(k)] = RRR_bySVD(X, Y, k);
- end
- % Y_pupildynexp_RRR = 1 - min(e);
- [~, k] = min(e);
- [Br, Bols, ~, ~] = RRR_bySVD(X, Y, k);
- Yhat2 = X * Br;
- Y_pupildynexp_RRR = var(Yhat2(:))/Y_totvar;
- % residual network response factoring out pupil dynamics
- % correlated portion (graph model)
- Y_res = Y - Yhat2;
- r = []; ypred = [];
- for n = 1:size(Y,2)
- X = Y_res;
- X(:,n) = [];
- [c,s,l] = pca(X);
- pcscore = s(:,1:find(l<0.1,1));
- mdl2 = fitlm(pcscore, Y_res(:,n));
- % mdl2 = fitlm(X, Y_res(:,n));
- r(n) = mdl2.Rsquared.Ordinary;
- ypred(:,n) = predict(mdl2,pcscore);
- end
- Y_net = var(ypred(:))/Y_totvar;
- % Y_net = mean(r);
- popResp_var = cat(1, popResp_var,[Y_stimexp, Y_pupildynexp_RRR, Y_net,areaID(k1,k2), k]);
- end
- end
- end
- end
- end
- figure, boxplot(popResp_var(:,1:3), 'whisker', 10)
- box off
- set(gca, 'Xticklabels', {'Stimulus','Pupil dynamics','Network'})
- ylabel('Variance explained')
- title('Partition variance of population neuron response ')
- %% 1D pupil dynamics
- binWidth = 100;
- smoothSD = 2;
- ind = 1;
- for k1 = 1:length(poolpupildata)
- if ~isempty(poolpupildata(k1).pupildata)
- pupildata = poolpupildata(k1).pupildata;
- if isfield(pupildata, 'pupilsync')
- pupilsync = pupildata.pupilsync;
- sync2p = table2array(poolpupildata(k1).sync2p);
- l0 = find(pupilsync(:,3)==1,1);
- l1 = find(pupilsync(:,3)==1,1,'last');
- pupildyn = [pupildata.eyearea(l0:l1)',pupildata.eyecenter(l0:l1,:),pupildata.videoscore];
- pupildyn(pupildyn(:,1)==0,1:3) = nan;
- pupilPC(k1,1:2) = [pupildata.video_PCdim, pupildata.video_PCvar];
- pupildyn_t = pupilsync(l0:l1,1:2);
- pupildyn_t = bsxfun(@minus, pupildyn_t, pupildyn_t(1,:))+1;
- pupildyn_match2p = [];
- for j = 1:size(pupildyn,2)
- tmp = interp1(pupildyn_t(:,1)/pupildyn_t(end,1), pupildyn(:,j), sync2p(:,1)/sync2p(end,1));
- pupildyn_match2p = cat(2, pupildyn_match2p, tmp);
- end
- imgPara = pooldata(k1,1).imgPara;
- % pupil dynamics bined per direction (2 sec window)
- pupildyn_bin = [];
- for i = 1:imgPara.stimrep
- for j = 1:imgPara.stim_type
- tmp = pupildyn_match2p(sync2p(:,3)==i & sync2p(:,5)==j,:);
- tmp1 = imresize(tmp, [8 size(tmp,2)]);
- pupildyn_bin = cat(1, pupildyn_bin, tmp1);
- end
- end
- X_pupildyn = pupildyn_bin;
- X_stim = repmat(stimflag, imgPara.stimrep, 1);
- for k2 = 1:4
- if ~isempty(pooldata(k1,k2).spiketrain) && length(pooldata(k1,k2).goodcell) > 5
- goodcell = pooldata(k1,k2).goodcell;
- spiketrain = pooldata(k1,k2).spiketrain(goodcell);
- num(k1,k2) = length(goodcell);
- spikecountAve = []; h = []; spikecountraw1 = [];
- spikecountraw2 = []; snr = [];
- for n = 1:length(goodcell)
- tmphist = [];
- stvec = [];
- for i = 1:imgPara.stimrep
- st1 = [];
- for j = 1:imgPara.stim_type
- st = spiketrain(n).st{i,j}*imgPara.dt;
- st(st<0) = [];
- st(st>imgPara.stim_time) = [];
- st1 = [st1, st+imgPara.stim_time*(j-1)];
- tmphist1 = histcounts(st, Twindow);
- tmphist = cat(1, tmphist, tmphist1');
- end
- stvec = vectCat(stvec, st1');
- end
- [rate , rateT] = myPSTH(stvec*1000, [0, imgPara.stim_time*imgPara.stim_type]*1000, binWidth, smoothSD);
- spikecountraw1(n,:) = tmphist;
- spikecountAve(n,:) = rate;
- end
- % total variance of population response
- Y = spikecountraw1';
- Y = bsxfun(@minus, Y, mean(Y,1));
- Y_totvar = var(Y(:));
- % variance explained by stimulus induced response
- Ym = mean(reshape(Y, 72,imgPara.stimrep,size(Y,2)), 2);
- Ym_var = var(Ym(:));
- Y_stimexp = Ym_var/Y_totvar;
- % residual population response after subtracting stimulus
- % induced portion (estimated by trial averaged response)
- Y = bsxfun(@minus, reshape(Y, 72,imgPara.stimrep,size(Y,2)), Ym);
- Y = reshape(Y,[],size(Y,3));
- Y_resvar = var(Y(:));
- % ordinary regression variance explained by pupil dynamics
- X = X_pupildyn;
- X(isnan(X)) = 0;
- [Br, Bols, ~, ~] = RRR_bySVD(X, Y, 1);
- Yhat2 = X * Br;
- Y_pupildynexp_RRR = var(Yhat2(:))/Y_totvar;
- popResp_var(ind, 6) = Y_pupildynexp_RRR;
- ind = ind+1;
- end
- end
- end
- end
- end
- figure, boxplot(popResp_var(:,[1,2,6,3]), 'whisker', 10)
- box off
- set(gca, 'Xticklabels', {'Stimulus','Pupil dynamics','1D Pupil dynamics','Network'})
- ylabel('Variance explained')
- title('Partition variance of population neuron response ')
FR_pupilAna.m at commit 4da24c0, under GPL-3.0 · at the source
Overview
- Department of Electrical and Computer Engineering, University of California, Santa Barbara, Santa Barbara, United States
- Dynamical Neurosciences, University of California, Santa Barbara, Santa Barbara, United States
Abstract
Among brain areas, axonal projections carry channels of information that can be mixed to varying degrees. Here, we assess the rules for the network consisting of the primary visual cortex and higher visual areas (V1-HVA) in mice. We use large field-of-view two-photon calcium imaging to measure correlated variability (i.e. noise correlations, NCs) among thousands of neurons, forming over a million unique pairs, distributed across multiple cortical areas simultaneously. The amplitude of NCs is proportional to functional connectivity in the network, and we find that they are robust, reproducible statistical measures and are remarkably similar across stimuli, thus providing effective constraints to network models. We used these NCs to measure the statistics of functional connectivity among tuning classes of neurons in V1 and HVAs. Using a data-driven clustering approach, we identify approximately 60 distinct tuning classes found in V1 and HVAs. We find that NCs are higher between neurons from the same tuning class, both within and across cortical areas. Thus, in the V1-HVA network, mixing of channels is avoided. Instead, distinct channels of visual information are broadcast within and across cortical areas, at both the micron and millimeter length scales. This principle for the functional organization and correlation structure at the individual neuron level across multiple cortical areas can inform and constrain computational theories of neocortical networks.
Reproduced under the paper's license (CC BY), from the paper cited above.
Repository
Its files are read in the Code ↔ Paper reader above, with 4 matches between paragraphs and lines of code.
yuyiyi/Broadcast_channel
4da24c0febfb9591ac9cd683920095e79cb429bb, 27 February 2026Availability: 1 check, the latest on 30 September 2026: the link answers
- 30 September 2026: the link answers
7 files
- FR_pupilAna.m, MATLAB, 263 lines, 2 matches
- MovieSpikecount.m, MATLAB, 30 lines
- NSC_compare.m, MATLAB, 459 lines, 1 match
- NSCmean_vsDist.m, MATLAB, 530 lines, 1 match
- SinGratSpikecount.m, MATLAB, 31 lines
- LICENSE, License, 674 lines
- README.md, Text, 2 lines
The paper's code and data availability statement is in the Data section.
Tracing map
Proposed by the machine: these links were found in the paper and verified at the source, without human review. The map will receive a Zenodo DOI once one of the paper's authors has validated it with their ORCID.
What the map holds:
- 1 repository of the authors' code, each at its verified commit, with its license and how the link was found in the paper;
- 5 scripts, each with its path and the digest of its content;
- 4 matches between paragraphs of the paper and lines of the code (method lexical-v1);
- neither the text of the paper nor the code itself.
Its JSON (tracing-map.json) is deposited on Zenodo with its DOI once the map is validated.
Data
Datasets cited
- crcns.org/
data-sets/ , at CRCNS; found in the text, “Tolerance of correlation calculation to…”methods
Data availability
Data and code generated in the current study are available on github https://
Reproduced under the paper's license (CC BY), from the paper cited above.
Versions
The history of this record: each version stored by the harvester or made by a correction of its authors or of the maintainers of its code, and what changed in its facts. The texts of the paper (its abstract, its availability statements) are not part of it; versions that changed only those are not listed.
Version 1, 30 September 2026: the first record
Recorded: type, language, journal, volume, pages, dates, 4 authors, 1 keyword, 8 MeSH terms, 5 funders, 72 references.
Cite
This paper
Yu, Y., Stirman, J. N., Dorsett, C. R., & Smith, S. L. (2026). Visual information is broadcast among cortical areas in discrete channels. eLife, 13, RP97848. https://
BibTeX
@article{yu2026visual,
author = {Yu, Yiyi and Stirman, Jeffery N and Dorsett, Christopher R and Smith, Spencer LaVere},
title = {{Visual information is broadcast among cortical areas in discrete channels}},
journal = {eLife},
year = {2026},
month = mar,
volume = {13},
pages = {RP97848},
publisher = {eLife Sciences Publications, Ltd},
issn = {2050-084X},
doi = {10.7554/
url = {https://
pmid = {41874539},
pmcid = {PMC13012721}
}
RIS
TY - JOUR
AU - Yu, Yiyi
AU - Stirman, Jeffery N
AU - Dorsett, Christopher R
AU - Smith, Spencer LaVere
TI - Visual information is broadcast among cortical areas in discrete channels
T2 - eLife
J2 - eLife
PY - 2026
DA - 2026/
VL - 13
SP - RP97848
SN - 2050-084X
PB - eLife Sciences Publications, Ltd
DO - 10.7554/
UR - https://
LA - en
ER -
CSL-JSON
{
"id": "10.7554/
"type": "article-journal",
"title": "Visual information is broadcast among cortical areas in discrete channels",
"container-title": "eLife",
"author": [
{
"family": "Yu",
"given": "Yiyi"
},
{
"family": "Stirman",
"given": "Jeffery N"
},
{
"family": "Dorsett",
"given": "Christopher R"
},
{
"family": "Smith",
"given": "Spencer LaVere"
}
],
"container-title-short":
"volume": "13",
"page": "RP97848",
"DOI": "10.7554/
"PMID": "41874539",
"PMCID": "PMC13012721",
"ISSN": "2050-084X",
"publisher": "eLife Sciences Publications, Ltd",
"URL": "https://
"language": "en",
"issued": {
"date-parts": [
[
2026,
3,
24
]
]
}
}
The tracing map gets a citation of its own once an author has validated it and it has a DOI.
Similar papers
The papers with a page that share the most with this one: the tools found in their code, their categories, datasets, cited references and authors, the rarest counting most.
- [1] doi:10.7554/elife.105213 [code]
- Mesoscale functional architecture in medial posterior parietal cortex.Journal: eLifeIn common: mouse, 12 references, 2 authors
- [2] doi:10.1038/s41592-023-02098-1
- The Cousa objective: a long-working distance air objective for multiphoton imaging in vivo.Journal: Nature methodsIn common: 7 references, 2 authors
- [3] doi:10.1371/journal.pcbi.1011667 [code]
- Modeling the diverse effects of divisive normalization on noise correlations.Journal: PLoS computational biologyIn common: Statistics and Machine Learning Toolbox, mouse, 14 references
- [4] doi:10.1038/s41467-024-50563-y [code]
- Flexible neural population dynamics govern the speed and stability of sensory encoding in mouse visual cortex.Journal: Nature communicationsIn common: shadedErrorBar, Image Processing Toolbox, Statistics and Machine Learning Toolbox, mouse, 12 references
- [5] doi:10.1117/1.nph.11.2.024307 [code]
- Comprehensive software suite for functional analysis and synaptic input mapping of dendritic spines imaged <i>in vivo</
i>. Journal: NeurophotonicsIn common: shadedErrorBar, Curve Fitting Toolbox, Image Processing Toolbox, 1 other tool, 5 references, author Yiyi Yu - [6] doi:10.1038/s41467-022-29656-z [code]
- Diversity of spatiotemporal coding reveals specialized visual processing streams in the mouse cortex.Journal: Nature communicationsIn common: Image Processing Toolbox, Statistics and Machine Learning Toolbox, mouse, 10 references
- [7] doi:10.1371/journal.pone.0271136 [code]
- Targeted dimensionality reduction enables reliable estimation of neural population coding accuracy from trial-limited data.Journal: PloS oneIn common: shadedErrorBar, Statistics and Machine Learning Toolbox, 10 references
- [8] doi:10.7554/elife.67258 [code]
- A general decoding strategy explains the relationship between behavior and correlated variability.Journal: eLifeIn common: Image Processing Toolbox, Statistics and Machine Learning Toolbox, 10 references
- [9] doi:10.1126/sciadv.abg5244 [code]
- Internally generated population activity in cortical networks hinders information transmission.Journal: Science advancesIn common: Image Processing Toolbox, Statistics and Machine Learning Toolbox, 10 references
- [10] doi:10.1126/sciadv.adz9632 [code]
- Population coding under the scale invariance of high-dimensional noise.Journal: Science advancesIn common: mouse, 11 references
Contribute
The authors of this paper can claim it, correct its record and validate its tracing map, and the maintainers of its code (its owner, or a public member of its organization) correct what it says of their repository; anyone signed in can ask for its removal. Every request goes to OSCR's own machine, which answers it; your account page follows them.
Sign in with ORCID to claim this paper as one of its authors, correct its record or validate its tracing map: when the paper's metadata lists your ORCID iD, you are recognized at once. Maintainers of its code: sign in with GitHub, then claim the repository on your account page.
Claim this paper
Correct its record
Say what each link of this record is, remove the ones that are not the paper's, add the ones that are missing. The correction becomes a new version of the record, in its Versions section.
Validate its tracing map
You validate the map as this page shows it: 1 repository of the authors' code, each at its verified commit and with its license, 5 scripts, and 4 matches between paragraphs and code (see the Code and Map sections). It then receives a DOI on Zenodo, with you (your ORCID iD) and OSCR as its creators; the code itself is not deposited.
The map's fingerprint: sha256:d4944b432df245e0…
Add the badge to the code's README
If you are an author or a maintainer of this paper's code, you can add this badge. It says what OSCR knows of the paper (its code, its validated tracing map) and links the code to this page. Paste one of these snippets under the README's title. Keep the two marks around it, so that the badge can be replaced in place and is never added twice. OSCR changes nothing in your repository.
Markdown
<!-- oscr-badge:start -->
[](https://openscicode.org/badge/doi/10.7554/elife.97848)
<!-- oscr-badge:end -->reStructuredText
.. oscr-badge:start
.. image:: https://openscicode.org/badge/doi/10.7554/elife.97848.svg
:target: https://openscicode.org/badge/doi/10.7554/elife.97848
:alt: OSCR
.. oscr-badge:endHTML
<!-- oscr-badge:start -->
<a href="https://openscicode.org/badge/doi/10.7554/elife.97848"><img src="https://openscicode.org/badge/doi/10.7554/elife.97848.svg" alt="OSCR"></a>
<!-- oscr-badge:end -->On GitHub, open the README, choose Edit (the pencil), paste the snippet under the title, then "Commit changes".
If you choose to, you can have the badge kept up to date for you, with oscr badge --write from the command line or with the GitHub Action in your repository's workflows. Every other form and option (a card, AsciiDoc, LaTeX, shields.io) is on the badge page.
Request its removal
To ask OSCR to remove this record, the copies of its authors' scripts or its tracing map, use the removal request page: signed in, you say who you are, what to remove and why, then review and confirm the request. Published rules decide every request (how).
Discussion, reproductions, activity
Discussion: code errors and mismatches between the code and the paper about this paper and its code, from readers and its authors, beside the paper and its tracing map.
Report a mismatch between the code and the paper · Report a code error (signed in)
Reproductions: reports from readers who ran the authors' code and did not get the paper's result, what they ran, with which environment, commit and data.
Report a reproduction failure (signed in)
Versions of its code: the releases of its code tied to a version of this paper (the preprint, the accepted manuscript, the version of record…), each with the tracing map versioned with it.
Activity: what happens around this paper: new versions of its record, its map's validation, discussions and reproductions. It opens with sign-in.
