OSCR

Association Between Motor Pathway Damage and Motor Deficit in Upper and Lower Limb in People With MS.

Overview

Authors: Mathilde Liffran1, Malo Gaubert1,2, Alice Dufey3, Elise Bannier1,2, Audrey Rico4,5,6, Jean‐Christophe Ferré1,2, Raphaël Chouteau3, Laure Michel3, Emmanuelle Le Page3, Virginie Callot4,5, Bertrand Audoin4,5,6, Sarah Demortière4,5,6, Benoît Combès1, Anne Kerbrat1,3
ORCID iDs: Mathilde Liffran, Malo Gaubert, Bertrand Audoin, Anne Kerbrat
  1. Univ Rennes, Inria, CNRS, Inserm, IRISA UMR 6074, Empenn U1228 Rennes France
  2. Univ Rennes, CHU Rennes (Service de Radiologie et Imagerie Médicale) Rennes France
  3. Univ Rennes, CHU Rennes (Service de Neurologie) Rennes France
  4. Assistance Publique‐Hopitaux de Marseille Hôpital Universitaire Timone, CEMEREM Marseille France
  5. Aix‐Marseille University, CNRS, CRMBM Marseille France
  6. Department of Neurology Assistance Publique‐Hopitaux de Marseille, Hôpital Universitaire Timone Marseille France
Institutions: Centre National de la Recherche Scientifique (France); Inserm (France); Institut de Recherche en Informatique et Systèmes Aléatoires (France); Empenn (France); Université de Rennes (France); Centre Hospitalier Universitaire de Rennes (France); Aix-Marseille Université (France); Assistance Publique Hôpitaux de Marseille (France); Centre de Résonance Magnétique Biologique et Médicale (France); Hôpital de la Timone (France)
Journal: Annals of clinical and translational neurology, article 10.1002/acn3.70418
Dates: received 18 December 2025; accepted 8 April 2026; published online 8 May 2026; in print May 2026
Type: Research article · Language: English
License: CC BY-NC-ND
Identifiers: DOI 10.1002/acn3.70418 · PMID 42104584 · PMCID PMC13394181 · OpenAlex W7160706768
Open access: gold, a free copy (OpenAlex)
Status: data only
Categories: structural MRI / diffusion (modality), human (organism), multiple sclerosis (population), clinical / translational (subfield)
Methods: Statistics, Machine learning, Connectivity, fMRI & imaging, Preprocessing
Keywords: corticospinal tract, motor deficits, MRI, multiple sclerosis, spinal cord
Topic: Multiple Sclerosis Research Studies (Pathology and Forensic Medicine, Medicine), according to OpenAlex
Funding: Rennes University Hospital; Institut des Neurosciences Cliniques de Rennes; ARSEP
Citations: not cited yet (Europe PMC); 60 references in the paper
Research resources: RRID:SCR_017072

Abstract

The abstract is not reproduced here: the paper's license (CC BY-NC-ND) does not allow it. Read it in the paper, at the publisher or on Europe PMC.

Code

The paper links to its data, not to its authors' code: see the Data section.

Tracing map

A tracing map links a paper to the code its authors published: this paper has none, so it has no map.

Data

Datasets cited

Data availability statement

The paper has a data availability statement. Its license (CC BY-NC-ND) does not allow reproducing it here; in short, from what the harvester recognized in it:

Read it in the paper: doi.org/10.1002/acn3.70418.

Versions

The history of this record: each version stored by the harvester or made by a correction of its authors or of the maintainers of its code, and what changed in its facts. The texts of the paper (its abstract, its availability statements) are not part of it; versions that changed only those are not listed.

Version 1, 28 September 2026: the first record

Recorded: type, language, journal, pages, dates, 14 authors, 5 keywords, 3 funders, 58 references, 1 RRID.

Cite

This paper

Liffran, M., Gaubert, M., Dufey, A., Bannier, E., Rico, A., Ferré, J., Chouteau, R., Michel, L., Le Page, E., Callot, V., Audoin, B., Demortière, S., Combès, B., & Kerbrat, A. (2026). Association Between Motor Pathway Damage and Motor Deficit in Upper and Lower Limb in People With MS. Annals of clinical and translational neurology, 10.1002/acn3.70418. https://doi.org/10.1002/acn3.70418

BibTeX

@article{liffran2026association,
author = {Liffran, Mathilde and Gaubert, Malo and Dufey, Alice and Bannier, Elise and Rico, Audrey and Ferré, Jean‐Christophe and Chouteau, Raphaël and Michel, Laure and Le Page, Emmanuelle and Callot, Virginie and Audoin, Bertrand and Demortière, Sarah and Combès, Benoît and Kerbrat, Anne},
title = {{Association Between Motor Pathway Damage and Motor Deficit in Upper and Lower Limb in People With MS}},
journal = {Annals of clinical and translational neurology},
year = {2026},
month = may,
pages = {10.1002/acn3.70418},
publisher = {Wiley},
issn = {2328-9503},
doi = {10.1002/acn3.70418},
url = {https://doi.org/10.1002/acn3.70418},
pmid = {42104584},
pmcid = {PMC13394181}
}

RIS

TY - JOUR
AU - Liffran, Mathilde
AU - Gaubert, Malo
AU - Dufey, Alice
AU - Bannier, Elise
AU - Rico, Audrey
AU - Ferré, Jean‐Christophe
AU - Chouteau, Raphaël
AU - Michel, Laure
AU - Le Page, Emmanuelle
AU - Callot, Virginie
AU - Audoin, Bertrand
AU - Demortière, Sarah
AU - Combès, Benoît
AU - Kerbrat, Anne
TI - Association Between Motor Pathway Damage and Motor Deficit in Upper and Lower Limb in People With MS
T2 - Annals of clinical and translational neurology
J2 - Ann Clin Transl Neurol
PY - 2026
DA - 2026/05/08
SP - 10.1002/acn3.70418
SN - 2328-9503
PB - Wiley
DO - 10.1002/acn3.70418
UR - https://doi.org/10.1002/acn3.70418
LA - en
ER -

CSL-JSON

{
"id": "10.1002/acn3.70418",
"type": "article-journal",
"title": "Association Between Motor Pathway Damage and Motor Deficit in Upper and Lower Limb in People With MS",
"container-title": "Annals of clinical and translational neurology",
"author": [
{
"family": "Liffran",
"given": "Mathilde"
},
{
"family": "Gaubert",
"given": "Malo"
},
{
"family": "Dufey",
"given": "Alice"
},
{
"family": "Bannier",
"given": "Elise"
},
{
"family": "Rico",
"given": "Audrey"
},
{
"family": "Ferré",
"given": "Jean‐Christophe"
},
{
"family": "Chouteau",
"given": "Raphaël"
},
{
"family": "Michel",
"given": "Laure"
},
{
"family": "Le Page",
"given": "Emmanuelle"
},
{
"family": "Callot",
"given": "Virginie"
},
{
"family": "Audoin",
"given": "Bertrand"
},
{
"family": "Demortière",
"given": "Sarah"
},
{
"family": "Combès",
"given": "Benoît"
},
{
"family": "Kerbrat",
"given": "Anne"
}
],
"container-title-short": "Ann Clin Transl Neurol",
"page": "10.1002/acn3.70418",
"DOI": "10.1002/acn3.70418",
"PMID": "42104584",
"PMCID": "PMC13394181",
"ISSN": "2328-9503",
"publisher": "Wiley",
"URL": "https://doi.org/10.1002/acn3.70418",
"language": "en",
"issued": {
"date-parts": [
[
2026,
5,
8
]
]
}
}

Similar papers

The papers with a page that share the most with this one: the tools found in their code, their categories, datasets, cited references and authors, the rarest counting most.

[1] doi:10.1093/braincomms/fcag140 [code]
Motor tract lesion mapping from the brain to the lower spinal cord in people with relapsing-remitting multiple sclerosis: exploring the association between lesion severity and functional consequences by limb.
Journal: Brain communications
In common: multiple sclerosis, structural MRI / diffusion, clinical / translational, 29 references, author Malo Gaubert
[2] doi:10.1002/nbm.70296 [code]
Quantitative Susceptibility Mapping of the Cervical Spinal Cord at 3T and Application to Multiple Sclerosis.
Journal: NMR in biomedicine
In common: multiple sclerosis, structural MRI / diffusion, 4 references
[3] doi:10.1136/jnnp-2025-335884 [code]
Diffusivity anisotropy signature of slowly expanding lesions predicts progression independent of relapse activity in multiple sclerosis.
Journal: Journal of neurology, neurosurgery, and psychiatry
In common: multiple sclerosis, structural MRI / diffusion, clinical / translational, 4 references
[4] doi:10.1162/imag.a.1251
Detection of slowly expanding lesions in people with multiple sclerosis using MRI: A scoping review.
Journal: Imaging neuroscience (Cambridge, Mass.)
In common: multiple sclerosis, structural MRI / diffusion, author Anne Kerbrat
[5] doi:10.1093/braincomms/fcag134 [code]
Neurophysiological, imaging and neurobiological markers of central fatigue in multiple sclerosis.
Journal: Brain communications
In common: multiple sclerosis, structural MRI / diffusion, 3 references
[6] doi:10.1186/s12883-026-05085-z
The use of routinely collected structural neuroimaging to identify cognitive impairment in multiple sclerosis.
Journal: BMC neurology
In common: multiple sclerosis, structural MRI / diffusion, clinical / translational, 2 references
[7] doi:10.1038/s41597-026-07184-5 [code]
A Multiple Sclerosis MRI Dataset with Tri-Mask Annotations for Lesion Segmentation.
Journal: Scientific data
In common: multiple sclerosis, structural MRI / diffusion, 2 references
[8] doi:10.1002/hbm.70593 [code]
Test-Retest Reliability of Sensorimotor Activity Measured With Spinal Cord fMRI.
Journal: Human brain mapping
In common: 3 references
[9] doi:10.1007/s00330-026-12577-6 [code]
Rule-based semi-automated method to segment black hole multiple sclerosis lesions on post-gadolinium 2D T1-weighted brain images.
Journal: European radiology
In common: multiple sclerosis, structural MRI / diffusion, 2 references
[10] doi:10.1016/j.nicl.2026.104007 [code]
A comparative study of deep learning for cortical lesion MRI segmentation with explainability analysis in multiple sclerosis.
Journal: NeuroImage. Clinical
In common: multiple sclerosis, structural MRI / diffusion, 2 references

Contribute

The authors of this paper can claim it, correct its record and validate its tracing map, and the maintainers of its code (its owner, or a public member of its organization) correct what it says of their repository; anyone signed in can ask for its removal. Every request goes to OSCR's own machine, which answers it; your account page follows them.

Sign in with ORCID to claim this paper as one of its authors, correct its record or validate its tracing map: when the paper's metadata lists your ORCID iD, you are recognized at once. Maintainers of its code: sign in with GitHub, then claim the repository on your account page.

Request its removal

To ask OSCR to remove this record, the copies of its authors' scripts or its tracing map, use the removal request page: signed in, you say who you are, what to remove and why, then review and confirm the request. Published rules decide every request (how).

Discussion, reproductions, activity

Discussion: questions and error reports about this paper and its code, from signed-in readers and its authors. It opens with sign-in.

Reproductions: reports from readers who ran the authors' code: what they reproduced, with which environment, commit and data. It opens with sign-in.

Activity: what happens around this paper: new versions of its record, its map's validation, discussions and reproductions. It opens with sign-in.