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Sodium-glucose cotransporter 2 inhibitors and the risk of late onset epilepsy: A real-world cohort study.

Overview

Authors: Bing‐Hua Lin1,2, Hui‐Min Huang1,2, Hui‐An Lin3,4, Sheng‐Feng Lin4,5,6,7,8
ORCID iDs: Bing‐Hua Lin, Hui‐Min Huang, Hui‐An Lin, Sheng‐Feng Lin
  1. School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan
  2. Department of Medical Education, Taipei Medical University Hospital, Taipei, Taiwan
  3. Department of Emergency Medicine, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan
  4. Department of Emergency Medicine, Taipei Medical University Hospital, Taipei, Taiwan
  5. Department of Public Health, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan
  6. School of Public Health, College of Public Health, Taipei Medical University, Taipei, Taiwan
  7. Center of Evidence‐Based Medicine, Taipei Medical University Hospital, Taipei, Taiwan
  8. Department of Medical Research, Taipei Medical University Hospital, Taipei, Taiwan
Institutions: Taipei Medical University Hospital (Taiwan); Taipei Medical University (Taiwan)
Journal: Epilepsia, volume 67, issue 7, pages 3444-3456
Dates: received 5 December 2025; accepted 19 March 2026; published online 6 April 2026; in print July 2026
Type: Research article · Language: English
License: CC BY-NC-ND
Identifiers: DOI 10.1002/epi.70239 · PMID 41940606 · PMCID PMC13360976 · OpenAlex W7150929568
Open access: hybrid, a free copy (OpenAlex)
Status: code on request
Categories: human (organism), other condition (population), epilepsy (population), clinical / translational (subfield)
Methods: Machine learning, Statistics
Keywords: antiseizure medications, late onset epilepsy, real‐world evidence, sodium‐glucose cotransporter 2 inhibitors (SGLT2i), type 2 diabetes mellitus
MeSH: Diabetes Mellitus, Type 2*, Epilepsy*, Sodium-Glucose Transporter 2 Inhibitors*, Age of Onset, Aged, Anticonvulsants, Cohort Studies, Female, Follow-Up Studies, Humans, Male, Middle Aged, Retrospective Studies, Risk Factors (* major topic)
Topic: Diabetes Treatment and Management (Endocrinology, Diabetes and Metabolism, Medicine), according to OpenAlex
Funding: Taipei Medical University
Citations: cited by 2 papers (Europe PMC); 49 references in the paper

Abstract

The abstract is not reproduced here: the paper's license (CC BY-NC-ND) does not allow it. Read it in the paper, at the publisher or on Europe PMC.

Code

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Data

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Code and data availability statement

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Read it in the paper: doi.org/10.1002/epi.70239.

Versions

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Version 1, 29 September 2026: the first record

Recorded: type, language, journal, volume, issue, pages, dates, 4 authors, 5 keywords, 14 MeSH terms, 1 funder, 49 references.

Cite

This paper

Lin, B., Huang, H., Lin, H., & Lin, S. (2026). Sodium-glucose cotransporter 2 inhibitors and the risk of late onset epilepsy: A real-world cohort study. Epilepsia, 67(7), 3444-3456. https://doi.org/10.1002/epi.70239

BibTeX

@article{lin2026sodium,
author = {Lin, Bing‐Hua and Huang, Hui‐Min and Lin, Hui‐An and Lin, Sheng‐Feng},
title = {{Sodium-glucose cotransporter 2 inhibitors and the risk of late onset epilepsy: A real-world cohort study}},
journal = {Epilepsia},
year = {2026},
month = apr,
volume = {67},
number = {7},
pages = {3444--3456},
publisher = {Wiley},
issn = {0013-9580},
doi = {10.1002/epi.70239},
url = {https://doi.org/10.1002/epi.70239},
pmid = {41940606},
pmcid = {PMC13360976}
}

RIS

TY - JOUR
AU - Lin, Bing‐Hua
AU - Huang, Hui‐Min
AU - Lin, Hui‐An
AU - Lin, Sheng‐Feng
TI - Sodium-glucose cotransporter 2 inhibitors and the risk of late onset epilepsy: A real-world cohort study
T2 - Epilepsia
J2 - Epilepsia
PY - 2026
DA - 2026/04/06
VL - 67
IS - 7
SP - 3444
EP - 3456
SN - 0013-9580
PB - Wiley
DO - 10.1002/epi.70239
UR - https://doi.org/10.1002/epi.70239
LA - en
ER -

CSL-JSON

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