Somatosensory Evoked BOLD-Signals With Ultra-High Temporal Resolution.
The 4 matches · 1 of them tie a paragraph to a whole file, not to given lines: a weak match, whose lines are not tinted
- [1] § Methods › fMRI Data Analysis and Statistical Assessment ↔ Analysis/D/D2_cluster_detection_4D.m, the whole file · a weak match · score 0.62 · cluster forming threshold, bwconncomp, connected, maps, temporal, voxels
- [2] § Methods › fMRI Data Analysis and Statistical Assessment ↔ Analysis/C/C12_glm_1stLevel.m, lines 126–139 · score 0.56 · auto correlation, threshold, filtering, temporal, model, fMRI
- [3] § Methods › fMRI Data Analysis and Statistical Assessment ↔ Analysis/C/C01_first_level_batch_BIDS_function.m, lines 127–152 · score 0.55 · high pass filter, regressor, realignment, beta, correlation, detrending
- [4] § Methods › Experimental Procedure ↔ Acquisition/experimental_script.m, lines 21–87 · score 0.52 · stimulus slice, parallel, triggers, log, stimulator, volume
Paper
Loaded from Europe PMC by your browser, not stored by OSCR: doi.org · Europe PMC
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The authors' code
MATLAB · 75 lines · 2.2 KB · no license · 1 match
- function [maxArea, keepers, L, file_4D, CC, info] = D2_cluster_detection_4D(dir_2nd, cluster_thresh_p, n2, min_size, num_bins, this_sign)
- % cluster_detection_4D searches for connected components throughout many 3D
- % NIFTIs that belong to statistical maps created through F-contrasts
- % OUTPUT:
- % maxArea: Voxel/Time-point count of the biggest cluster in this analysis
- % keepers: 4D map of all the clusters resulting from this analysis
- % under the assigned parameters (see input)
- % L: 4D labels of all clusters resulting from the analysis
- % INPUT:
- % dir_2nd: directory containg all the 2nd level F-maps
- % cluster_thresh_p: cluster-forming threshold as a p-value
- % n2: second degrees of freedom of the F-test
- % min_size: cluster size cutoff for the output "keepers"
- % num_bins: number of temporal bins or number of F-maps to
- % include
- % cluster_thresh_p = 0.001; % like uncorrected
- n1 = 1; % df 1: each F-map separatly
- % cluster_thresh_F = tinv(1-cluster_thresh_p,n2);
- cluster_thresh_T = tinv(1-cluster_thresh_p,n2); % t-contrasts: one - and one +
- if this_sign == -1
- con_nums = 1:num_bins;
- else
- con_nums = (num_bins+1):num_bins*2;
- end
- counter = 0;
- for sz = con_nums
- counter = counter + 1;
- if sz < 10
- t_str = [dir_2nd filesep 'spmT_000' num2str(sz) '.nii'];
- elseif sz < 100
- t_str = [dir_2nd filesep 'spmT_00' num2str(sz) '.nii'];
- else
- t_str = [dir_2nd filesep 'spmT_0' num2str(sz) '.nii'];
- end
- if counter == 1
- temp = niftiread(t_str);
- file_4D = zeros([size(temp), num_bins]);
- clear temp
- end
- file_4D(:,:,:,counter) = niftiread(t_str);
- end
- info = niftiinfo(t_str);
- binary_4D = zeros(size(file_4D));
- binary_4D(file_4D>cluster_thresh_T) = 1;
- CC = bwconncomp(binary_4D);
- L = labelmatrix(CC);
- prop = regionprops(CC,"Area");
- [maxArea,maxIdx] = max([prop.Area]);
- [cluster_sizes, sortingIdx] = sort([prop.Area], 'descend'); % so that B = A(I)
- kickIdx = sortingIdx(cluster_sizes<min_size);
- idx = setdiff(1:CC.NumObjects,kickIdx);
- keepers = cc2bw(CC,ObjectsToKeep=idx);
- end
D2_cluster_detection_4D.m at commit a5aaaaa, no license · at the source
Overview
- Neurocomputation and Neuroimaging Unit (NNU), Freie Universität Berlin, Berlin, Germany
- Institut für Psychologie, Otto‐von‐Guericke‐Universität Magdeburg, Magdeburg, Germany
Abstract
The blood oxygen level‐dependent (BOLD) signal has been instrumental in characterizing brain activity. While the spatial resolution of fMRI continues to improve, relatively few methods have focused on enhancing and leveraging temporal resolution to investigate the spatiotemporal dynamics of the hemodynamic response. In this study, we applied a reordering method to achieve ultra‐high temporal resolution (60 ms) in data acquired during a somatosensory stimulation paradigm. We then used a finite impulse response model (FIR) for each participant (N = 31) to preserve the temporal dynamics in the statistical analysis. At the group level, we employed an ANOVA combined with 4D nonparametric permutation testing to identify significant signal changes in time across the whole brain. Our results characterize the hemodynamic response in terms of both its temporal and spatial patterns and reveal distinct differences in response shapes within the somatosensory system. This method introduces a time‐resolved approach to BOLD signal analysis, drawing inspiration from grand‐average techniques commonly used in EEG research.
Reproduced under the paper's license (CC BY-NC), from the paper cited above.
Repository
Its files are read in the Code ↔ Paper reader above, with 4 matches between paragraphs and lines of code.
Neurocomputation-and-Neuroimaging-Unit/Somatosensory_Evoked_BOLD-signals
a5aaaaad6231789201e40d870b23439e42009691, 16 January 2026Availability: 1 check, the latest on 30 September 2026: the link answers
- 30 September 2026: the link answers
30 files
- Acquisition/
config_io.m , MATLAB, 13 lines - Acquisition/
experimental_script.m , MATLAB, 165 lines, 1 match - Acquisition/
test_double.m , MATLAB, 16 lines - Analysis/
A/ , MATLAB, 156 linesA0_dicom2bids_batch.m - Analysis/
A/ , MATLAB, 300 linesA1_dicm2bids.m - Analysis/
B/ , MATLAB, 408 linesB0_prepro_SEBs_Batch_fun ction.m - Analysis/
B/ , MATLAB, 49 linesB1_Realignment_all_runs. m - Analysis/
B/ , MATLAB, 546 linesB2_detrending_lmgs.m - Analysis/
B/ , MATLAB, 60 linesB3_calculate_SEBS.m - Analysis/
B/ , MATLAB, 40 linesB4_coregister_est.m - Analysis/
B/ , MATLAB, 59 linesB5_segmentation.m - Analysis/
B/ , MATLAB, 42 linesB6_normalization_run.m - Analysis/
B/ , MATLAB, 35 linesB7_smoothing_run.m - Analysis/
C/ , MATLAB, 267 lines, 1 matchC01_first_level_batch_BI DS_function.m - Analysis/
C/ , MATLAB, 71 linesC02_second_level_batch_B IDS.m - Analysis/
C/ , MATLAB, 41 linesC03_2nd_level_shuffle_fu nction.m - Analysis/
C/ , MATLAB, 153 lines, 1 matchC12_glm_1stLevel.m - Analysis/
C/ , MATLAB, 37 linesC13_contrast_1stLevel.m - Analysis/
C/ , MATLAB, 139 linesC14_1st_level_FIR.m - Analysis/
C/ , MATLAB, 89 linesC21_2ndLevel_OneSampleTe st.m - Analysis/
C/ , MATLAB, 70 linesC22_2ndLevel_1wayANOVA.m - Analysis/
C/ , MATLAB, 78 linesC31_1st_level_FIR_shuff. m - Analysis/
D/ , MATLAB, 395 linesD0_permutation_statistic s_batch.m - Analysis/
D/ , MATLAB, 31 linesD1_contrasts_function.m - Analysis/
D/ , MATLAB, 75 lines, 1 matchD2_cluster_detection_4D. m - Analysis/
D/ , MATLAB, 158 linesROI_on_FIR.m - Analysis/
D/ , MATLAB, 69 linesROI_on_GLM.m - Analysis/
D/ , MATLAB, 61 linesget_region_from_anatomy. m - Analysis/
D/ , MATLAB, 27 linesget_region_from_anatomy_ HCPex.m - README.md, Text, 30 lines
Tracing map
Proposed by the machine: these links were found in the paper and verified at the source, without human review. The map will receive a Zenodo DOI once one of the paper's authors has validated it with their ORCID.
What the map holds:
- 1 repository of the authors' code, each at its verified commit, with its license and how the link was found in the paper;
- 29 scripts, each with its path and the digest of its content;
- 4 matches between paragraphs of the paper and lines of the code (method lexical-v1);
- neither the text of the paper nor the code itself.
Its JSON (tracing-map.json) is deposited on Zenodo with its DOI once the map is validated.
Data
No dataset and no data link were found in the paper.
Data Availability Statement
The data that support the findings of this study are available on request from the corresponding author. The data are not publicly available due to privacy or ethical restrictions.
Reproduced under the paper's license (CC BY-NC), from the paper cited above.
Versions
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Version 1, 30 September 2026: the first record
Recorded: type, language, journal, volume, issue, pages, dates, 4 authors, 6 keywords, 14 MeSH terms, 39 references.
Cite
This paper
Wesolek, S., Nierhaus, T., Ostwald, D., & Blankenburg, F. (2026). Somatosensory Evoked BOLD-Signals With Ultra-High Temporal Resolution. Human brain mapping, 47(4), e70507. https://
BibTeX
@article{wesolek2026soma
author = {Wesolek, Sara and Nierhaus, Till and Ostwald, Dirk and Blankenburg, Felix},
title = {{Somatosensory Evoked BOLD-Signals With Ultra-High Temporal Resolution}},
journal = {Human brain mapping},
year = {2026},
month = mar,
volume = {47},
number = {4},
pages = {e70507},
publisher = {Wiley},
issn = {1065-9471},
doi = {10.1002/
url = {https://
pmid = {41834676},
pmcid = {PMC13093736}
}
RIS
TY - JOUR
AU - Wesolek, Sara
AU - Nierhaus, Till
AU - Ostwald, Dirk
AU - Blankenburg, Felix
TI - Somatosensory Evoked BOLD-Signals With Ultra-High Temporal Resolution
T2 - Human brain mapping
J2 - Hum Brain Mapp
PY - 2026
DA - 2026/
VL - 47
IS - 4
SP - e70507
SN - 1065-9471
PB - Wiley
DO - 10.1002/
UR - https://
LA - en
ER -
CSL-JSON
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"id": "10.1002/
"type": "article-journal",
"title": "Somatosensory Evoked BOLD-Signals With Ultra-High Temporal Resolution",
"container-title": "Human brain mapping",
"author": [
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"family": "Wesolek",
"given": "Sara"
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{
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"given": "Till"
},
{
"family": "Ostwald",
"given": "Dirk"
},
{
"family": "Blankenburg",
"given": "Felix"
}
],
"container-title-short":
"volume": "47",
"issue": "4",
"page": "e70507",
"DOI": "10.1002/
"PMID": "41834676",
"PMCID": "PMC13093736",
"ISSN": "1065-9471",
"publisher": "Wiley",
"URL": "https://
"language": "en",
"issued": {
"date-parts": [
[
2026,
3,
1
]
]
}
}
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