Impaired spatial coding and neuronal hyperactivity in the medial entorhinal cortex of aged APP knock-in mice.
The 2 matches
- [1] § STAR★METHODS › QUANTIFICATION AND STATISTICAL ANALYSIS ↔ DHARMa/R/tests.R, lines 402–520 · score 0.53 · zero inflation, glmmTMB, outliers, Pearson, nonparametric, ratios
- [2] § STAR★METHODS › QUANTIFICATION AND STATISTICAL ANALYSIS ↔ glmmTMB/R/diagnose.R, lines 1–35 · score 0.51 · zero inflation, Diagnostic, glmmTMB, logit, coefficients, ratios
Paper
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The authors' code
R · 903 lines · 56 KB · gnu · 1 match
tests.R at commit c9dbcee, under gnu · at the source
Overview
- Taub Institute for Research on Alzheimer’s Disease and the Aging Brain, Columbia University Irving Medical Center, New York, NY 10032, USA
- Burke Neurological Institute, White Plains, NY 10605, USA
- Center for Neural Science, New York University, New York, NY 10003, USA
- Department of Neuroscience, Columbia University Irving Medical Center, New York, NY 10027, USA
- Center for Theoretical Neuroscience, Columbia University, New York, NY 10027, USA
- Zuckerman Mind Brain Behavior Institute, Columbia University, New York, NY 10027, USA
- Kavli Institute for Brain Science, Columbia University, New York, NY 10027, USA
- Department of Pathology and Cell Biology, Columbia University Irving Medical Center, New York, NY 10032, USA
- Lead contact
Abstract
Advanced amyloid beta (Aβ) pathology is associated with aberrant neuronal network activity and cognitive impairment in preclinical Alzheimer’s disease (AD) models. Here, we assess Aβ pathology’s impact on spatial information processing in the medial entorhinal cortex (MEC) of 18-month AppNL-G-F/
Reproduced under the paper's license (CC BY), from the paper cited above.
Repositories
Its files are read in the Code ↔ Paper reader above, with 2 matches between paragraphs and lines of code.
Zenodo 19040105
Availability: 1 check, the latest on 27 September 2026: the link answers (HTTP 200)
- 27 September 2026: the link answers (HTTP 200)
1 file
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klusta-team/klustakwik
d8b750107fef53996957d774dfa3ec71f2442462, 21 April 2015Availability: 1 check, the latest on 27 September 2026: the link answers
- 27 September 2026: the link answers
19 files, not copied: shown from their source
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cluster_mask_stats.py — Python, 155 lines, shown from its source - devtools/
filter_noise_spikes.py — Python, 136 lines, shown from its source - globalswitches.h — C/C++, 43 lines, shown from its source
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glmmTMB/glmmTMB
db725d143d529c93c55cf7baa7402dc5135fe6ff, 23 September 2026Availability: 1 check, the latest on 27 September 2026: the link answers
- 27 September 2026: the link answers
201 files, not copied: shown from their source
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florianhartig/DHARMa
c9dbcee2eec12904e505dd8c7c4f1f8d61ec1f79, 25 September 2026Availability: 1 check, the latest on 27 September 2026: the link answers
- 27 September 2026: the link answers
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hussainilab/rodriguez-et-al-cell-reports-2026
7772cfa1cce93cad101419229805151e27f5beea, 14 May 2026Availability: 1 check, the latest on 27 September 2026: the link answers
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Data
No dataset and no data link were found in the paper.
Data and code availability
Source data for all figures will be made freely available on the Hussaini Lab GitHub page (https://
All original code used for data analysis will be made freely available on the Hussaini Lab GitHub page.
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Reproduced under the paper's license (CC BY), from the paper cited above.
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Version 2, 28 September 2026
- Publisher: — → Cell Press
- Authors: added S Abid Hussaini (0000-0002-3921-9021); removed S Abid Hussaini
Version 1, 27 September 2026: the first record
Recorded: type, language, journal, volume, issue, pages, dates, 10 authors, 11 keywords, 13 MeSH terms, 3 funders, 140 references, 10 RRIDs.
Cite
This paper
Rodriguez, G. A., Aoun, A., Rothenberg, E. F., Shetler, C. O., Posani, L., Vajram, S. V., Tedesco, T., Sharma, A., Fusi, S., & Hussaini, S. A. (2026). Impaired spatial coding and neuronal hyperactivity in the medial entorhinal cortex of aged APP knock-in mice. Cell reports, 45(6), 117505. https://
BibTeX
@article{rodriguez2026im
author = {Rodriguez, Gustavo A and Aoun, Andrew and Rothenberg, Eva F and Shetler, C Oliver and Posani, Lorenzo and Vajram, Srujan V and Tedesco, Thomas and Sharma, Anurag and Fusi, Stefano and Hussaini, S Abid},
title = {{Impaired spatial coding and neuronal hyperactivity in the medial entorhinal cortex of aged APP knock-in mice}},
journal = {Cell reports},
year = {2026},
month = jun,
volume = {45},
number = {6},
pages = {117505},
publisher = {Cell Press},
issn = {2211-1247},
doi = {10.1016/
url = {https://
pmid = {42250220},
pmcid = {PMC13560757}
}
RIS
TY - JOUR
AU - Rodriguez, Gustavo A
AU - Aoun, Andrew
AU - Rothenberg, Eva F
AU - Shetler, C Oliver
AU - Posani, Lorenzo
AU - Vajram, Srujan V
AU - Tedesco, Thomas
AU - Sharma, Anurag
AU - Fusi, Stefano
AU - Hussaini, S Abid
TI - Impaired spatial coding and neuronal hyperactivity in the medial entorhinal cortex of aged APP knock-in mice
T2 - Cell reports
J2 - Cell Rep
PY - 2026
DA - 2026/
VL - 45
IS - 6
SP - 117505
SN - 2211-1247
PB - Cell Press
DO - 10.1016/
UR - https://
LA - en
ER -
CSL-JSON
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