An Adnp frameshift variant disrupts Wnt signalling inducing chromatocytoskeletal defects and autism-related behaviour in male mice.
Overview
and 6 other authors
Izuho Hatada13, Ligia Mateiu1, Giacomo Cavalli2, Emanuela Pasciuto3,4, Wim Vanden Berghe14, R Frank Kooy114 affiliations
- Cognitive Genetics (CONGET), Department of Biomedical Sciences, University of Antwerp, Antwerp, Belgium
- Institute of Human Genetics, CNRS, University of Montpellier, Montpellier, France
- VIB Center for Molecular Neurology, VIB, Antwerp, Belgium
- Department of Biomedical Sciences, University of Antwerp, Antwerp, Belgium
- Laboratory of Cell Biology and Histology, Department of Veterinary Sciences, University of Antwerp, Antwerp, Belgium
- Antwerp Centre for Advanced Microscopy (ACAM), University of Antwerp, Antwerp, Belgium
- Laboratory of Neurochemistry and Behavior, Experimental Neurobiology Unit, Department of Biomedical Sciences, University of Antwerp, Antwerp, Belgium
- Department of Neurology and Alzheimer Research Center, University of Groningen, and University Medical Centre Groningen (UMCG), Groningen, the Netherlands
- Department of Neurology and Memory Clinic, Hospital Network Antwerp (ZNA) Middelheim and HogeBeuken, Antwerp, Belgium
- Institute Born-Bunge (IBB) Neurobiobank, University of Antwerp, Antwerp, Belgium
- Université Bourgogne Europe, INSERM Research Center U1231, 21070, Dijon, France
- Institut NeuroMyoGène, Unité Physiopathologie et Génétique du Neurone et du Muscle, CNRS UMR 5261, Inserm U1315, Université Claude Bernard Lyon 1, 69008, Lyon, France
- Laboratory of Genome Science, Biosignal Genome Resource Center, Institute for Molecular and Cellular Regulation, Gunma University, Gunma, Japan
- Cell Death Signalling - Epigenetics lab, Department of Biomedical Sciences, University of Antwerp, Antwerp, Belgium
Abstract
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Data
Datasets cited
- geo:GSE319683, at NCBI GEO; found in “Data sharing statement”
Data availability statement
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- it points to a dataset: NCBI GEO GSE319683
Read it in the paper: doi.org/10.1016/j.ebiom.2026.106309.
Versions
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Version 2, 28 September 2026
- Authors: added Clara Milián Alastruey (0000-0002-9772-7462); Sofie Thys (0000-0002-7080-3592); Isabel Pintelon (0000-0003-2901-4679); Debby Van Dam (0000-0003-4739-6076); Ligia Mateiu (0000-0002-2655-3581); removed Clara Milián Alastruey; Sofie Thys; Isabel Pintelon; Debby Van Dam; Ligia Mateiu
Version 1, 28 September 2026: the first record
Recorded: type, language, journal, volume, pages, dates, 26 authors, 5 keywords, 11 MeSH terms, 5 funders, 125 references, 19 RRIDs.
Cite
This paper
D'Incal, C. P., Cappuyns, E., Paldi, F., van der Lei, M. B., Annear, D. J., Alastruey, C. M., Sokolova, D., Elinck, E., De Man, K., Konings, A., Huyghebaert, J., Thys, S., Pintelon, I., Verschuuren, M., Calus, E., Van Dam, D., De Deyn, P. P., Nguyen, S., Yalcin, B., . . . Kooy, R. F. (2026). An Adnp frameshift variant disrupts Wnt signalling inducing chromatocytoskeletal defects and autism-related behaviour in male mice. EBioMedicine, 128, 106309. https://
BibTeX
@article{dincal2026adnp,
author = {D'Incal, Claudio Peter and Cappuyns, Elisa and Paldi, Flora and van der Lei, Mathijs B and Annear, Dale John and Alastruey, Clara Milián and Sokolova, Dimitra and Elinck, Ellen and De Man, Kevin and Konings, Anthony and Huyghebaert, Jolien and Thys, Sofie and Pintelon, Isabel and Verschuuren, Marlies and Calus, Elke and Van Dam, Debby and De Deyn, Peter P and Nguyen, Sylvie and Yalcin, Binnaz and Horii, Takuro and Hatada, Izuho and Mateiu, Ligia and Cavalli, Giacomo and Pasciuto, Emanuela and Berghe, Wim Vanden and Kooy, R Frank},
title = {{An Adnp frameshift variant disrupts Wnt signalling inducing chromatocytoskeletal defects and autism-related behaviour in male mice}},
journal = {EBioMedicine},
year = {2026},
month = may,
volume = {128},
pages = {106309},
publisher = {Elsevier},
issn = {2352-3964},
doi = {10.1016/
url = {https://
pmid = {42208149},
pmcid = {PMC13235381}
}
RIS
TY - JOUR
AU - D'Incal, Claudio Peter
AU - Cappuyns, Elisa
AU - Paldi, Flora
AU - van der Lei, Mathijs B
AU - Annear, Dale John
AU - Alastruey, Clara Milián
AU - Sokolova, Dimitra
AU - Elinck, Ellen
AU - De Man, Kevin
AU - Konings, Anthony
AU - Huyghebaert, Jolien
AU - Thys, Sofie
AU - Pintelon, Isabel
AU - Verschuuren, Marlies
AU - Calus, Elke
AU - Van Dam, Debby
AU - De Deyn, Peter P
AU - Nguyen, Sylvie
AU - Yalcin, Binnaz
AU - Horii, Takuro
AU - Hatada, Izuho
AU - Mateiu, Ligia
AU - Cavalli, Giacomo
AU - Pasciuto, Emanuela
AU - Berghe, Wim Vanden
AU - Kooy, R Frank
TI - An Adnp frameshift variant disrupts Wnt signalling inducing chromatocytoskeletal defects and autism-related behaviour in male mice
T2 - EBioMedicine
J2 - EBioMedicine
PY - 2026
DA - 2026/
VL - 128
SP - 106309
SN - 2352-3964
PB - Elsevier
DO - 10.1016/
UR - https://
LA - en
ER -
CSL-JSON
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