GWAS meta-analysis of cerebrospinal fluid Alzheimer's biomarkers reveals loci regulating lipids, brain volume and autophagy.

1. Department of Psychiatry, Washington University School of Medicine, St. Louis, MO USA
2. NeuroGenomics and Informatics Center, Washington University School of Medicine, St. Louis, MO USA
3. Alzheimer Center Amsterdam, Neurology, Vrije Universiteit Amsterdam, Amsterdam UMC Location VUmc, Amsterdam, The Netherlands
4. Amsterdam Neuroscience, Neurodegeneration, Amsterdam, The Netherlands
5. Centre for Genomic and Experimental Medicine, Institute of Genetics and Cancer, The University of Edinburgh, Edinburgh, UK
6. Human Genetics and Causal Biology, Eisai Center for Genetics-Guided Dementia Discovery, Eisai Inc, Cambridge, MA USA
7. Division of Neurogenetics and Molecular Psychiatry, Department of Psychiatry and Psychotherapy, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany
8. Estudios en Neurociencias y Sistemas Complejos (ENyS), CONICET-HEC-UNAJ, Buenos Aires, Argentina
9. Department of Psychiatry and Neurochemistry, Institute of Neuroscience and physiology, the Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden
10. Barcelonaβeta Brain Research Center (BBRC), Pasqual Maragall Foundation, Barcelona, Spain
11. Centre for Genomic Regulation (CRG), Barcelona Institute of Science and Technology (BIST), Barcelona, Spain
12. Hospital del Mar Research Institute, Barcelona, Spain
13. Lübeck Interdisciplinary Platform for Genome Analytics, University of Lübeck, Lübeck, Germany
14. Ace Alzheimer Center Barcelona, Universitat Internacional de Catalunya, Barcelona, Spain
15. Department of Neurology, Washington University School of Medicine, St. Louis, MO USA
16. UK Dementia Research Institute at Cardiff, Cardiff, UK
17. Vanderbilt Memory and Alzheimer’s Center, Vanderbilt University Medical Center, Nashville, TN USA
18. Delft Bioinformatics Lab, Delft University of Technology, Delft, The Netherlands
19. Neuropsychiatric Epidemiology Unit, Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, the Sahlgrenska Academy, Centre for Ageing and Health (AGECAP) at the University of Gothenburg, Gothenburg, Sweden
20. Department of Neuropsychiatry, Region Västra Götaland, Sahlgrenska University Hospital, Gothenburg, Sweden
21. Reina Sofia Alzheimer Center, CIEN Foundation, ISCIII, Madrid, Spain
22. Centro de Investigación Biomédica en Red de Enfermedades Neurodegenerativas (CIBERNED), Instituto de Salud Carlos III, Madrid, Spain
23. Neurology Service, Marqués de Valdecilla University Hospital, Santander, Spain
24. Department of Cognitive Disorders and Old Age Psychiatry, University Hospital Bonn, Bonn, Germany
25. German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany
26. German Center for Neurodegenerative Diseases (DZNE), Berlin, Germany
27. Charité–Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Institute of Psychiatry and Psychotherapy, Berlin, Germany
28. Department of Biomedical Sciences, University of Antwerp, Antwerp, Belgium
29. Complex Genetics of Alzheimer’s Disease Lab, VIB Center for Molecular Neurology, VIB, Antwerp, Belgium
30. Univ. Lille, Inserm, CHU Lille, Institut Pasteur de Lille, LabEx DISTALZ-U1167-RID-AGE Facteurs de Risque et Determiants moléculaires des maladies liées au vieillissement, Lille, France
31. Institute of Biomedicine, University of Eastern Finland, Kuopio, Finland
32. Martin-Luther-University Halle-Wittenberg, University Clinic and Outpatient Clinic for Psychiatry, Psychotherapy and Psychosomatics, Halle (Saale), Germany
33. LVR-University Hospital Essen, Department of Psychiatry and Psychotherapy, Medical Faculty, University of Duisburg-Essen, Essen, Germany
34. Department of Geriatric Psychiatry, Central Institute for Mental Health Mannheim, Faculty Mannheim, University of Heidelberg, Heidelberg, Germany
35. German Center for Neurodegenerative Diseases (DZNE), Magdeburg, Germany
36. Institute of Cognitive Neurology and Dementia Research (IKND), Otto-von-Guericke University, Magdeburg, Germany
37. Center for Cognitive Disorders, Department of Psychiatry and Psychotherapy, Technical University of Munich, TUM School of Medicine and Health, Munich, Germany
38. Department of Psychiatry and Psychotherapy, University Medical Center Goettingen, Goettingen, Germany
39. German Center for Neurodegenerative Diseases (DZNE), Goettingen, Germany
40. Medical Science Department, iBiMED, Aveiro, Portugal
41. Department of Neurology, UZ Leuven, Leuven, Belgium
42. Department of Neurology, Universitair Ziekenhuis Brussel and Neuroprotection and Neuromodulation (NEUR) Research Group, Center for Neurosciences (C4N), Vrije Universiteit Brussel (VUB), Brussels, Belgium
43. Institute of Human Genetics, University of Bonn, School of Medicine & University Hospital Bonn, Bonn, Germany
44. Institute of Medical Biometry, Informatics and Epidemiology, University Hospital of Bonn, Bonn, Germany
45. 1st Department of Neurology, Medical school, Aristotle University of Thessaloniki, Thessaloniki, Greece
46. 1st Department of Neurology, Aiginition Hospital, Medical School, National and Kapodistrian University of Athens, Athens, Greece
47. Depatment of Neurology, Columbia University, New York, NY USA
48. Sant Pau Memory Unit, Institut de Recerca Sant Pau, Department of Neurology, Hospital de la Santa Creu I Sant Pau, Universitat Autònoma de Barcelona, Barcelona, Spain
49. Department of Neurology, Hospital Universitario Donostia, San Sebastian, Spain
50. Neurosciences Area, Instituto Biodonostia, San Sebastian, Spain
51. Unitat de Genètica Molecular, Institut de Biomedicina de València-CSIC, Valencia, Spain
52. Centro de Biología Molecular Severo Ochoa (UAM-CSIC), Madrid, Spain
53. Instituto de Investigacion Sanitaria ‘Hospital la Paz’ (IdIPaz), Madrid, Spain
54. Universidad Autónoma de Madrid, Madrid, Spain
55. Alzheimer’s disease and other cognitive disorders unit. Service of Neurology. Hospital Clínic of Barcelona. Institut d’Investigacions Biomèdiques August Pi i Sunyer, University of Barcelona, Barcelona, Spain
56. Laboratorio de Genética. Hospital Universitario Central de Asturias, Oviedo, Spain
57. Instituto de Investigación Sanitaria del Principado de Asturias (ISPA), Av. del Hospital Universitario, Asturias, Spain
58. Unidad de Trastornos del Movimiento, Servicio de Neurología y Neurofisiología. Instituto de Biomedicina de Sevilla (IBiS), Hospital Universitario Virgen del Rocío/CSIC/Universidad de Sevilla, Seville, Spain
59. Unidad Clínica de Enfermedades Infecciosas y Microbiología. Hospital Universitario de Valme, Sevilla, Spain
60. Depatamento de Especialidades Quirúrgicas, Bioquímica e Inmunología. Facultad de Medicina. Universidad de Málaga, Málaga, Spain
61. Unitat Trastorns Cognitius, Hospital Universitari Santa Maria de Lleida, Lleida, Spain
62. Institut de Recerca Biomedica de Lleida (IRBLLeida), Lleida, Spain
63. Alzheimer Research Center & Memory Clinic, Andalusian Institute for Neuroscience, Málaga, Spain
64. Maastricht University, Department of Psychiatry & Neuropsychologie, Alzheimer Center Limburg, Maastricht, the Netherlands
65. Neurology department Erasmus MC University Medical Center, Rotterdam, The Netherlands
66. Internal Medicine Department, Erasmus MC University Medical Center, Rotterdam, The Netherlands
67. Genomics of Neurodegenerative Diseases and Aging, Human Genetics, Vrije Universiteit Amsterdam, Amsterdam UMC location VUmc, Amsterdam, The Netherlands
68. German Center for Neurodegenerative Diseases (DZNE), Tübingen, Germany
69. Section for Dementia Research, Hertie Institute for Clinical Brain Research and Department of Psychiatry and Psychotherapy, University of Tübingen, Tübingen, Germany
70. German Center for Neurodegenerative Diseases (DZNE), Rostock, Germany
71. Department of Psychosomatic Medicine, Rostock University Medical Center, Rostock, Germany
72. Department of Psychiatry and Psychotherapy, Charité – Universitätsmedizin Berlin, Berlin, Germany
73. Department of Psychiatry and Psychotherapy, Klinikum rechts der Isar Technical University Munich, Munich, Germany
74. German Center for Neurodegenerative Diseases (DZNE Munich), Munich, Germany
75. Department of Psychiatry and Psychotherapy, University Hospital, LMU Munich, Munich, Germany
76. Munich Cluster for Systems Neurology (SyNergy) Munich, Munich, Germany
77. Ageing Epidemiology Research Unit, School of Public Health, Imperial College London, London, UK
78. Institute for Stroke and Dementia Research (ISD), University Hospital, LMU Munich, Munich, Germany
79. Institute of Human Genetics; University of Bonn, School of Medicine & University Hospital Bonn, Bonn, Germany
80. Department of Psychiatry and Psychotherapy, Universitätsklinikum Erlangen, and Friedrich-Alexander Universität Erlangen-Nürnberg, Erlangen, Germany
81. Department of Neurodegeneration Diagnostics, Medical University of Białystok, Białystok, Poland
82. Sorbonne University, Alzheimer Precision Medicine (APM), AP-HP, Pitié-Salpêtrière Hospital, Boulevard de l’hôpital, Paris, France
83. Division of General Psychiatry, Dept. of Psychiatry and Psychotherapy, Medical University of Vienna, Vienna, Austria
84. Department of Neurodegenerative Diseases and Geriatric Psychiatry, University Hospital Bonn, Medical Faculty, Bonn, Germany
85. Department of Psychiatry, Harvard Medical School McLean Hospital, Belmont, MA USA
86. Division of Neurogeriatrics, Department NVS, Karolinska Institutet, Center for Alzheimer Research, Stockholm, Sweden
87. Unit for Hereditary Dementias, Karolinska University Hospital-Solna, Stockholm, Sweden
88. Aging Research Center, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet and Stockholm University, Stockholm, Sweden
89. Université Paris-Saclay, CEA, Centre National de Recherche en Génomique Humaine, Evry, France
90. Inserm, Bordeaux Population Health Research Center, UMR 1219, Univ. Bordeaux, ISPED, CIC 1401-EC, Univ Bordeaux, Bordeaux, France
91. CHU de Bordeaux, Pole santé publique, Bordeaux, France
92. Department of Psychiatry and Psychotherapy, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany
93. Cluster of Excellence Cellular Stress Responses in Aging-associated Diseases (CECAD), University of Cologne, Cologne, Germany
94. Department of Neurosciences, Leuven Brain Institute, KU Leuven, Leuven, Belgium
95. Department of Epidemiology, ErasmusMC, Rotterdam, The Netherlands
96. Nuffield Department of Population Health, University of Oxford, Oxford, UK
97. Centre for Artificial Intelligence in Precision Medicine, University of Oxford, Oxford, UK
98. Univ.Lille, Inserm, CHULille, Lille Neuroscience & Cognition, UMR-S1172, Lille, France
99. Université de Paris, EA 4468, APHP, Hôpital Broca, Paris, France
100. Department of Neurosurgery, Kuopio University Hospital and Institute of Clinical Medicine-Neurosurgery, University of Eastern Finland, Kuopio, Finland
101. Department of Neurology, Institute of Clinical Medicine, University of Eastern Finland, Kuopio, Finland
102. Department of Neurology, NeuroCenter, Kuopio University Hospital, Kuopio, Finland
103. Department of Public Health and Caring Sciences/Clinical Geriatrics, Uppsala University, Uppsala, Sweden
104. Department of Radiology and Nuclear Medicine, Amsterdam UMC location VUmc, Amsterdam, Netherlands
105. Amsterdam Neuroscience, Brain Imaging, Amsterdam, The Netherlands
106. Laboratory for Cognitive Neurology, KU Leuven, Leuven, Belgium
107. Laboratory for Complex Genetics, KU Leuven, Leuven, Belgium
108. Institució Catalana de Recerca i Estudis Avançats (ICREA), Barcelona, Spain
109. Department of Experimental and Health Sciences, Institute of Evolutionary Biology (CSIC-UPF), Universitat Pompeu Fabra, Barcelona, Spain
110. Clinical neurochemistry Laboratory, Sahlgrenska University Hospital, Mölndal, Sweden
111. Paris Brain Institute, ICM, Pitié-Salpêtrière Hospital, Sorbonne University, Paris, France
112. UK Dementia Research Institute at UCL, London, UK
113. Wisconsin Alzheimer’s Disease Research Center, University of Wisconsin School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI USA
114. Glenn Biggs Institute for Alzheimer’s & Neurodegenerative Diseases and Department of Microbiology, Immunology and Molecular Genetics, Long School of Medicine, University of Texas Health Science Center, San Antonio, TX USA
115. Department of Pathology and Laboratory Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA USA
116. Department of Medicine, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI USA
117. Department of Population Health Sciences, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI USA
118. Unit of Neurodegenerative diseases, Department of Neurology, University Hospital Germans Trias i Pujol and The Germans Trias i Pujol Research Institute (IGTP) Badalona, Barcelona, Spain
119. Veterans Affairs Northwest Mental Illness Research, Education, and Clinical Center, Seattle, WA USA
120. Department of Psychiatry and Behavioral Sciences, University of Washington, Seattle, WA USA
121. Department of Neurodegenerative Disease, UCL Institute of Neurology, London, UK
122. Indiana Alzheimer’s Disease Research Center, Department of Radiology and Imaging Sciences, Indiana University School of Medicine, Indianapolis, Indiana, USA
123. Department of Genetics, Washington University School of Medicine, St. Louis, MO USA
124. Hope Center for Neurological Disorders, Washington University School of Medicine, St. Louis, MO USA
125. Ronald M. Loeb Center for Alzheimer’s Disease, Icahn School of Medicine at Mount Sinai, New York, NY USA
126. Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY USA
127. Nash Family Department of Neuroscience, Icahn School of Medicine at Mount Sinai, New York, NY USA
128. Department of Psychiatry, Saarland University, Homburg, Germany
129. Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD USA
130. Centre for Precision Health, School of Medical Health Sciences, Edith Cowan University, Joondalup, WA Australia
131. Krembil Brain Institute, University Health Network, Toronto, ON Canada
132. Tanz Centre for Research in Neurodegenerative Diseases, Departments of Medicine and Laboratory Medicine & Pathobiology, University of Toronto, Toronto, ON Canada
133. Department of Public Health and Caring Sciences, Molecular Geriatrics, Rudbeck Laboratory, Uppsala University, Uppsala, Sweden
134. Department of Neurology, Alzheimer Center Amsterdam, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam UMC, VUmc, Amsterdam, the Netherlands
135. Department of Neurobiology, Care Sciences and Society, Division of Neurogeriatrics, Karolinska Institutet, Stockholm, Sweden
136. Alzheimer Center Limburg, School for Mental Health and Neuroscience, Maastricht University, Maastricht, the Netherlands
137. Scottish Brain Sciences, Scottish Gas Murrayfield Stadium, Edinburgh, UK
138. School of Medicine, University of St Andrews, St Andrews, UK
139. Division of Psychological Medicine and Clinical Neuroscience, School of Medicine, Cardiff University, Cardiff, UK
140. Department of Human Genetics, Radboud University Medical Center, Nijgmegen, the Netherlands
141. Neuroscience, Janssen Research & Development LLC, Titusville, NJ USA
142. JRD Data Science, Janssen Research & Development LLC, Titusville, NJ USA
143. CHDI Management Inc., Princeton, NJ USA
144. Department of Psychiatry, Glenn Biggs Institute for Alzheimer’s and Neurodegenerative Diseases, San Antonio, TX USA
145. Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Disease (CECAD), University of Cologne, Cologne, Germany
146. Section Genomics of Neurodegenerative Diseases and Aging, Human Genetics, Vrije Universiteit Amsterdam, Amsterdam UMC location VUmc, Amsterdam, The Netherlands

@article{timsina2026gwas,
author = {Timsina, Jigyasha and Jiang, Chenyang and McCartney, Daniel L and Tao, Feifei and Dalmasso, Maria Carolina and Najar, Jenna and Anastasi, Federica and Ohlei, Olena and Puerta Fuentes, Raquel and Yang, Chenyu and Bradley, Joseph and Western, Daniel and Ali, Muhammad and Wang, Ciyang and Yang, Chengran and Wu, Ying and Liu, Menghan and Budde, John and Williams, Julie and Mahoney, Rebecca and Castillo Morales, Atahualpa and Hohman, Timothy J and Dumitrescu, Logan and Wang, Ting-Chen and Tesi, Niccolo’ and Kern, Silke and Waern, Margda and Skoog, Ingmar and van Harten, Argonde and Pijnenburg, Yolande A L and van der Flier, Wiesje M and Sánchez-Juan, Pascual and Rodriguez-Rodriguez, Eloy and Kleineidam, Luca and Peters, Oliver and Schneider, Anja and Küçükali, Fahri and Bellenguez, Céline and Grenier-Boley, Benjamin and Heikkinen, Sami and de Rojas, Itziar and Rujescu, Dan and Scherbaum, Norbert and Hausner, Lucrezia and Düzel, Emrah and Grimmer, Timo and Wiltfang, Jens and Vandenberghe, Rik and Engelborghs, Sebastiaan and Heilmann-Heimbach, Stefanie and Schmid, Matthias and Tegos, Thomas and Scarmeas, Nikolaos and Dols-Icardo, Oriol and Moreno, Fermin and Pérez-Tur, Jordi and Bullido, María J and Sánchez-Valle, Raquel and Álvarez, Victoria and García-González, Pablo and Mir, Pablo and Real, Luis M and Piñol-Ripoll, Gerard and García-Alberca, Jose María and Seelaar, Harro and Ramakers, Inez and Papma, Janne and Hulsman, Marc and Laske, Christoph and Teipel, Stefan and Priller, Josef and Perneczky, Robert and Buerger, Katharina and Nöthen, Markus M and Lewczuk, Piotr and Kornhuber, Johannes and Hampel, Harald and Giegling, Ina and Goldhardt, Oliver and Diehl-Schmid, Janine and Andrade, Victor and Heneka, Michael MT and Frölich, Lutz and Vogelgsang, Jonathan and Graff, Caroline and Thonberg, Hakan and Ullgren, Abbe and Papenberg, Goran and Deleuze, Jean-François and Dufouil, Carole and Wagner, Michael and Jessen, Frank and Holstege, Henne and van Duijn, Cornelia and Lebouvier, Thibaud and Hannon, Olivier and Leinonen, Ville and Soininen, Hilkka and Herukka, Sanna-Kaisa and Giedraitis, Vilmantas and Löwenmark, Malin and Kilander, Lena and Genius, Patricia and Rodríguez, Blanca and Luckett, Emma S and Navarro, Arcadi and Cano, Amanda and Marquié, Marta and Blennow, Kaj and Zetterberg, Henrik and Lleo, Alberto and Boada, Mercè and Ruiz, Agustin and Lee, Virginia Man-Yee and Van Deerlin, Vivianna M and Deming, Yuetiva and Johnson, Sterling C and Engelman, Corinne D and Pastor, Pau and Alvarez, Ignacio and Peskind, Elaine R and Heslegrave, Amanda J and Saykin, Andrew J and Nho, Kwangsik and Schindler, Suzanne E and Morris, John C and Holtzman, David M and McDade, Eric and Renton, Alan E and Goate, Alison and Ibanez, Laura and Riemenschneider, Matthias and Albert, Marilyn S and Laws, Simon M and Porter, Tenielle and O’Brien, Eleanor K and Shaw, Leslie M and Tijms, Betty M and Ingelsson, Martin and Visser, Pieter Jelle and Hiltunen, Mikko and Sleegers, Kristel and Ritchie, Craig W and Sims, Rebecca and Belloy, Michael and Lambert, Jean-Charles and Vilor-Tejedor, Natalia and Fernández, Maria Victoria and Li, Qingqin S and Nagle, Michael W and Marioni, Riccardo E and Ramirez, Alfredo and Bertram, Lars and van der Lee, Sven J and Cruchaga, Carlos},
title = {{GWAS meta-analysis of cerebrospinal fluid Alzheimer's biomarkers reveals loci regulating lipids, brain volume and autophagy}},
journal = {Nature communications},
year = {2026},
month = apr,
volume = {17},
number = {1},
pages = {7385},
publisher = {Nature Publishing Group},
issn = {2041-1723},
doi = {10.1038/s41467-026-71682-8},
url = {https://doi.org/10.1038/s41467-026-71682-8},
pmid = {42014397},
pmcid = {PMC13402690}
}

TY - JOUR
AU - Timsina, Jigyasha
AU - Jiang, Chenyang
AU - McCartney, Daniel L
AU - Tao, Feifei
AU - Dalmasso, Maria Carolina
AU - Najar, Jenna
AU - Anastasi, Federica
AU - Ohlei, Olena
AU - Puerta Fuentes, Raquel
AU - Yang, Chenyu
AU - Bradley, Joseph
AU - Western, Daniel
AU - Ali, Muhammad
AU - Wang, Ciyang
AU - Yang, Chengran
AU - Wu, Ying
AU - Liu, Menghan
AU - Budde, John
AU - Williams, Julie
AU - Mahoney, Rebecca
AU - Castillo Morales, Atahualpa
AU - Hohman, Timothy J
AU - Dumitrescu, Logan
AU - Wang, Ting-Chen
AU - Tesi, Niccolo’
AU - Kern, Silke
AU - Waern, Margda
AU - Skoog, Ingmar
AU - van Harten, Argonde
AU - Pijnenburg, Yolande A L
AU - van der Flier, Wiesje M
AU - Sánchez-Juan, Pascual
AU - Rodriguez-Rodriguez, Eloy
AU - Kleineidam, Luca
AU - Peters, Oliver
AU - Schneider, Anja
AU - Küçükali, Fahri
AU - Bellenguez, Céline
AU - Grenier-Boley, Benjamin
AU - Heikkinen, Sami
AU - de Rojas, Itziar
AU - Rujescu, Dan
AU - Scherbaum, Norbert
AU - Hausner, Lucrezia
AU - Düzel, Emrah
AU - Grimmer, Timo
AU - Wiltfang, Jens
AU - Vandenberghe, Rik
AU - Engelborghs, Sebastiaan
AU - Heilmann-Heimbach, Stefanie
AU - Schmid, Matthias
AU - Tegos, Thomas
AU - Scarmeas, Nikolaos
AU - Dols-Icardo, Oriol
AU - Moreno, Fermin
AU - Pérez-Tur, Jordi
AU - Bullido, María J
AU - Sánchez-Valle, Raquel
AU - Álvarez, Victoria
AU - García-González, Pablo
AU - Mir, Pablo
AU - Real, Luis M
AU - Piñol-Ripoll, Gerard
AU - García-Alberca, Jose María
AU - Seelaar, Harro
AU - Ramakers, Inez
AU - Papma, Janne
AU - Hulsman, Marc
AU - Laske, Christoph
AU - Teipel, Stefan
AU - Priller, Josef
AU - Perneczky, Robert
AU - Buerger, Katharina
AU - Nöthen, Markus M
AU - Lewczuk, Piotr
AU - Kornhuber, Johannes
AU - Hampel, Harald
AU - Giegling, Ina
AU - Goldhardt, Oliver
AU - Diehl-Schmid, Janine
AU - Andrade, Victor
AU - Heneka, Michael MT
AU - Frölich, Lutz
AU - Vogelgsang, Jonathan
AU - Graff, Caroline
AU - Thonberg, Hakan
AU - Ullgren, Abbe
AU - Papenberg, Goran
AU - Deleuze, Jean-François
AU - Dufouil, Carole
AU - Wagner, Michael
AU - Jessen, Frank
AU - Holstege, Henne
AU - van Duijn, Cornelia
AU - Lebouvier, Thibaud
AU - Hannon, Olivier
AU - Leinonen, Ville
AU - Soininen, Hilkka
AU - Herukka, Sanna-Kaisa
AU - Giedraitis, Vilmantas
AU - Löwenmark, Malin
AU - Kilander, Lena
AU - Genius, Patricia
AU - Rodríguez, Blanca
AU - Luckett, Emma S
AU - Navarro, Arcadi
AU - Cano, Amanda
AU - Marquié, Marta
AU - Blennow, Kaj
AU - Zetterberg, Henrik
AU - Lleo, Alberto
AU - Boada, Mercè
AU - Ruiz, Agustin
AU - Lee, Virginia Man-Yee
AU - Van Deerlin, Vivianna M
AU - Deming, Yuetiva
AU - Johnson, Sterling C
AU - Engelman, Corinne D
AU - Pastor, Pau
AU - Alvarez, Ignacio
AU - Peskind, Elaine R
AU - Heslegrave, Amanda J
AU - Saykin, Andrew J
AU - Nho, Kwangsik
AU - Schindler, Suzanne E
AU - Morris, John C
AU - Holtzman, David M
AU - McDade, Eric
AU - Renton, Alan E
AU - Goate, Alison
AU - Ibanez, Laura
AU - Riemenschneider, Matthias
AU - Albert, Marilyn S
AU - Laws, Simon M
AU - Porter, Tenielle
AU - O’Brien, Eleanor K
AU - Shaw, Leslie M
AU - Tijms, Betty M
AU - Ingelsson, Martin
AU - Visser, Pieter Jelle
AU - Hiltunen, Mikko
AU - Sleegers, Kristel
AU - Ritchie, Craig W
AU - Sims, Rebecca
AU - Belloy, Michael
AU - Lambert, Jean-Charles
AU - Vilor-Tejedor, Natalia
AU - Fernández, Maria Victoria
AU - Li, Qingqin S
AU - Nagle, Michael W
AU - Marioni, Riccardo E
AU - Ramirez, Alfredo
AU - Bertram, Lars
AU - van der Lee, Sven J
AU - Cruchaga, Carlos
TI - GWAS meta-analysis of cerebrospinal fluid Alzheimer's biomarkers reveals loci regulating lipids, brain volume and autophagy
T2 - Nature communications
J2 - Nat Commun
PY - 2026
DA - 2026/04/21
VL - 17
IS - 1
SP - 7385
SN - 2041-1723
PB - Nature Publishing Group
DO - 10.1038/s41467-026-71682-8
UR - https://doi.org/10.1038/s41467-026-71682-8
LA - en
ER -

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"title": "GWAS meta-analysis of cerebrospinal fluid Alzheimer's biomarkers reveals loci regulating lipids, brain volume and autophagy",
"container-title": "Nature communications",
"author": [
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{
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{
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"given": "Sven J"
},
{
"family": "Cruchaga",
"given": "Carlos"
}
],
"container-title-short": "Nat Commun",
"volume": "17",
"issue": "1",
"page": "7385",
"DOI": "10.1038/s41467-026-71682-8",
"PMID": "42014397",
"PMCID": "PMC13402690",
"ISSN": "2041-1723",
"publisher": "Nature Publishing Group",
"URL": "https://doi.org/10.1038/s41467-026-71682-8",
"language": "en",
"issued": {
"date-parts": [
[
2026,
4,
21
]
]
}
}