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Targeting dopamine transporter for treating social transmission of depression-like behaviors in male mice.

Overview

Authors: Kun Zhang1,2, Dake Song2,3, Yingying Zhang1,2, Le Yang1, Ruixia Liu2, Hengxin Gong2, Qi Yang1, Min Wang2, Xinshang Wang3, Yumei Wu2, Weiwei Hu4, Shuibing Liu2,3, Minggao Zhao1
ORCID iDs: Kun Zhang, Yumei Wu, Weiwei Hu
  1. Precision Pharmacy & Drug Development Center, Department of Pharmacy, Tangdu Hospital, Fourth Military Medical University, Xi’an, Shaanxi China
  2. Department of Pharmacology, School of Pharmacy, Fourth Military Medical University, Xi’an, Shaanxi China
  3. State Key Laboratory of Oral & Maxillofacial Reconstruction and Regeneration, National Clinical Research Center for Oral Diseases, Shaanxi Engineering Research Center for Dental Materials and Advanced Manufacture, Department of Pharmacy, School of Stomatology, Fourth Military Medical University, Xi’an, Shaanxi China
  4. Department of Pharmacology and Department of Pharmacy of the Second Affiliated Hospital, NHC and CAMS Key Laboratory of Medical Neurobiology, School of Basic Medical Sciences, College of Pharmaceutical Sciences, Zhejiang University School of Medicine, Hangzhou, Zhejiang China
Institutions: Tang Du Hospital (China); Air Force Medical University (China); Stomatology Hospital (China); Second Affiliated Hospital of Zhejiang University (China); Zhejiang University (China)
Journal: Nature communications, volume 17, issue 1, article 7641
Dates: received 29 July 2025; accepted 29 May 2026; published online 16 June 2026
Type: Research article · Language: English
License: CC BY-NC-ND
Identifiers: DOI 10.1038/s41467-026-74206-6 · PMID 42303982 · PMCID PMC13433770 · OpenAlex W7164926070
Open access: gold, a free copy (OpenAlex)
Status: data only
Categories: mouse (organism), depression (population), systems (subfield)
Methods: Spectral & time-frequency, Statistics, Evoked potentials, Physiology & signal measures
Keywords: Prefrontal cortex, Empathy
MeSH: Depression*, Dopamine Plasma Membrane Transport Proteins*, Amygdala, Animals, Behavior, Animal, Dopamine, Male, Mice, Mice, Inbred C57BL, Odorants, Olfactory Bulb, Prefrontal Cortex, Social Behavior, Ventral Tegmental Area (* major topic)
Topic: Neurotransmitter Receptor Influence on Behavior (Cellular and Molecular Neuroscience, Neuroscience), according to OpenAlex
Funding: National Natural Science Foundation of China (82571721, 82221001, 82430047, 82471537); Fourth Military Medical University
Citations: cited by 1 paper (Europe PMC); 91 references in the paper
Research resources: RRID:Addgene_159902

Abstract

The abstract is not reproduced here: the paper's license (CC BY-NC-ND) does not allow it. Read it in the paper, at the publisher or on Europe PMC.

Code

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The paper's code and data availability statement is in the Data section.

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Data

Datasets cited

Code and data availability statement

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Read it in the paper: doi.org/10.1038/s41467-026-74206-6.

Versions

The history of this record: each version stored by the harvester or made by a correction of its authors or of the maintainers of its code, and what changed in its facts. The texts of the paper (its abstract, its availability statements) are not part of it; versions that changed only those are not listed.

Version 2, 28 September 2026

  • Funding: added National Natural Science Foundation of China: 82571721, 82221001, 82430047, 82471537; Fourth Military Medical University

Version 1, 27 September 2026: the first record

Recorded: type, language, journal, volume, issue, pages, dates, 13 authors, 2 keywords, 14 MeSH terms, 91 references, 1 RRID.

Cite

This paper

Zhang, K., Song, D., Zhang, Y., Yang, L., Liu, R., Gong, H., Yang, Q., Wang, M., Wang, X., Wu, Y., Hu, W., Liu, S., & Zhao, M. (2026). Targeting dopamine transporter for treating social transmission of depression-like behaviors in male mice. Nature communications, 17(1), 7641. https://doi.org/10.1038/s41467-026-74206-6

BibTeX

@article{zhang2026targeting,
author = {Zhang, Kun and Song, Dake and Zhang, Yingying and Yang, Le and Liu, Ruixia and Gong, Hengxin and Yang, Qi and Wang, Min and Wang, Xinshang and Wu, Yumei and Hu, Weiwei and Liu, Shuibing and Zhao, Minggao},
title = {{Targeting dopamine transporter for treating social transmission of depression-like behaviors in male mice}},
journal = {Nature communications},
year = {2026},
month = jun,
volume = {17},
number = {1},
pages = {7641},
publisher = {Nature Publishing Group},
issn = {2041-1723},
doi = {10.1038/s41467-026-74206-6},
url = {https://doi.org/10.1038/s41467-026-74206-6},
pmid = {42303982},
pmcid = {PMC13433770}
}

RIS

TY - JOUR
AU - Zhang, Kun
AU - Song, Dake
AU - Zhang, Yingying
AU - Yang, Le
AU - Liu, Ruixia
AU - Gong, Hengxin
AU - Yang, Qi
AU - Wang, Min
AU - Wang, Xinshang
AU - Wu, Yumei
AU - Hu, Weiwei
AU - Liu, Shuibing
AU - Zhao, Minggao
TI - Targeting dopamine transporter for treating social transmission of depression-like behaviors in male mice
T2 - Nature communications
J2 - Nat Commun
PY - 2026
DA - 2026/06/16
VL - 17
IS - 1
SP - 7641
SN - 2041-1723
PB - Nature Publishing Group
DO - 10.1038/s41467-026-74206-6
UR - https://doi.org/10.1038/s41467-026-74206-6
LA - en
ER -

CSL-JSON

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