OSCR

Gut microbiota-GABA axis dysregulation underlies polystyrene microplastic (PS-MP) neurotoxicity in rainbow trout: a role for oxidative stress and blood-brain barrier disruption.

Overview

Authors: Fang Ma1,2, Pan Zheng1, Wenli Wang1, Jiaxuan Dong1, Xiangjun Zhou1,2, Zhiyun Lin1, Xiajiao Nian1
  1. School of Bioengineering and Technology, Tianshui Normal University,Tianshui, Gansu Province PR China
  2. Key Laboratory of Resource Utilization of Agricultural Solid Waste in Gansu Province, Tianshui Normal University,Tianshui, Gansu Province PR China
Institutions: Tianshui Normal University (China)
Journal: NPJ biofilms and microbiomes, volume 12, issue 1, article 99
Dates: received 23 August 2025; accepted 25 April 2026; published online 7 May 2026
Type: Research article · Language: English
License: CC BY-NC-ND
Identifiers: DOI 10.1038/s41522-026-00995-9 · PMID 42098161 · PMCID PMC13212561 · OpenAlex W7160519245
Open access: gold, a free copy (OpenAlex)
Status: data only
Categories: genetics / omics (modality), other (organism), cellular / molecular (subfield)
Methods: Statistics
Keywords: Microbiology, Neuroscience
MeSH: Blood-Brain Barrier*, gamma-Aminobutyric Acid*, Gastrointestinal Microbiome*, Microplastics*, Neurotoxicity Syndromes*, Oncorhynchus mykiss*, Oxidative Stress*, Polystyrenes*, Animals, Brain, Multiomics (* major topic)
Topic: Microplastics and Plastic Pollution (Pollution, Environmental Science), according to OpenAlex
Funding: National Natural Science Foundation of China (32260258)
Citations: cited by 1 paper (Europe PMC); 42 references in the paper

Abstract

The abstract is not reproduced here: the paper's license (CC BY-NC-ND) does not allow it. Read it in the paper, at the publisher or on Europe PMC.

Code

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Data

Datasets cited

Data availability statement

The paper has a data availability statement. Its license (CC BY-NC-ND) does not allow reproducing it here; in short, from what the harvester recognized in it:

Read it in the paper: doi.org/10.1038/s41522-026-00995-9.

Versions

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Version 1, 28 September 2026: the first record

Recorded: type, language, journal, volume, issue, pages, dates, 7 authors, 2 keywords, 11 MeSH terms, 1 funder, 42 references.

Cite

This paper

Ma, F., Zheng, P., Wang, W., Dong, J., Zhou, X., Lin, Z., & Nian, X. (2026). Gut microbiota-GABA axis dysregulation underlies polystyrene microplastic (PS-MP) neurotoxicity in rainbow trout: a role for oxidative stress and blood-brain barrier disruption. NPJ biofilms and microbiomes, 12(1), 99. https://doi.org/10.1038/s41522-026-00995-9

BibTeX

@article{ma2026gut,
author = {Ma, Fang and Zheng, Pan and Wang, Wenli and Dong, Jiaxuan and Zhou, Xiangjun and Lin, Zhiyun and Nian, Xiajiao},
title = {{Gut microbiota-GABA axis dysregulation underlies polystyrene microplastic (PS-MP) neurotoxicity in rainbow trout: a role for oxidative stress and blood-brain barrier disruption}},
journal = {NPJ biofilms and microbiomes},
year = {2026},
month = may,
volume = {12},
number = {1},
pages = {99},
publisher = {Nature Publishing Group},
issn = {2055-5008},
doi = {10.1038/s41522-026-00995-9},
url = {https://doi.org/10.1038/s41522-026-00995-9},
pmid = {42098161},
pmcid = {PMC13212561}
}

RIS

TY - JOUR
AU - Ma, Fang
AU - Zheng, Pan
AU - Wang, Wenli
AU - Dong, Jiaxuan
AU - Zhou, Xiangjun
AU - Lin, Zhiyun
AU - Nian, Xiajiao
TI - Gut microbiota-GABA axis dysregulation underlies polystyrene microplastic (PS-MP) neurotoxicity in rainbow trout: a role for oxidative stress and blood-brain barrier disruption
T2 - NPJ biofilms and microbiomes
J2 - NPJ Biofilms Microbiomes
PY - 2026
DA - 2026/05/07
VL - 12
IS - 1
SP - 99
SN - 2055-5008
PB - Nature Publishing Group
DO - 10.1038/s41522-026-00995-9
UR - https://doi.org/10.1038/s41522-026-00995-9
LA - en
ER -

CSL-JSON

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