Genomics of perivascular space burden unravels early mechanisms of cerebral small vessel disease.

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statgen/METAL

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bulik/ldsc

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erwinerdem/STEAP

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pboutinaud/SHIVA_PVS

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JonJala/mtag

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perslab/CELLECT

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thewonlab/H-MAGMA

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Tools found in the code: BEDTools, Keras, Matplotlib, NiBabel, NumPy, pandas, SciPy, seaborn, Snakemake, statsmodels, TensorFlow, tidyverse

OverviewAuthors: Marie-Gabrielle Duperron, Maria J. Knol, Quentin Le Grand, Tavia E. Evans, Aniket Mishra, Ami Tsuchida, Gennady Roshchupkin, Takahiro Konuma, David-Alexandre Trégouët, Jose Rafael Romero, Stefan Frenzel, Michelle Luciano, Edith Hofer, Mathieu Bourgey, Nicole D. Dueker, Pilar Delgado, Saima Hilal, Rick M. Tankard, Florian Dubost, Jean Shinand 69 other authorsYasaman Saba, Nicola J. Armstrong, Constance Bordes, Mark E. Bastin, Alexa Beiser, Henry Brodaty, Robin Bülow, Caty Carrera, Christopher Chen, Ching-Yu Cheng, Ian J. Deary, Piyush G. Gampawar, Jayandra J. Himali, Jiyang Jiang, Takahisa Kawaguchi, Shuo Li, Melissa Macalli, Pascale Marquis, Zoe Morris, Susana Muñoz Maniega, Susumu Miyamoto, Masakazu Okawa, Matthew Paradise, Pedram Parva, Tatjana Rundek, Muralidharan Sargurupremraj, Sabrina Schilling, Kazuya Setoh, Omar Soukarieh, Yasuharu Tabara, Alexander Teumer, Anbupalam Thalamuthu, Julian N. Trollor, Maria C. Valdés Hernández, Meike W. Vernooij, Uwe Völker, Katharina Wittfeld, Tien Yin Wong, Margaret J. Wright, Junyi Zhang, Wanting Zhao, Yi-Cheng Zhu, Helena Schmidt, Perminder S. Sachdev, Wei Wen, Kazumichi Yoshida, Anne Joutel, Claudia L. Satizabal, Ralph L. Sacco, Guillaume Bourque, the CHARGE consortium, Mark Lathrop, Tomas Paus, Israel Fernandez-Cadenas, Qiong Yang, Bernard Mazoyer, Philippe Boutinaud, Yukinori Okada, Hans J. Grabe, Karen A. Mather, Reinhold Schmidt, Marc Joliot, M. Arfan Ikram, Fumihiko Matsuda, Christophe Tzourio, Joanna M. Wardlaw, Sudha Seshadri, Hieab H. H. Adams, Stéphanie Debette
Journal: Nature medicine
Published: 17 April 2023
Type: Research article
Status: code verified (how the code is found and verified)
DOI: 10.1038/s41591-023-02268-w
License: CC BY
Institutions: Université de Bordeaux (France), Inserm (France), Centre Hospitalier Universitaire de Bordeaux (France), Institut des Maladies Neurodégénératives (France), Bordeaux Population Health (France), Erasmus MC (Netherlands), Centre National de la Recherche Scientifique (France), Commissariat à l'Énergie Atomique et aux Énergies Alternatives (France), The University of Osaka (Japan), Boston University (United States), Framingham Heart Study (United States), Universitätsmedizin Greifswald (Germany), University of Edinburgh (United Kingdom), Medical University of Graz (Austria), McGill University (Canada), University of Miami (United States), Universitat Autònoma de Barcelona (Spain), Vall d'Hebron Institut de Recerca (Spain), Vall d'Hebron Hospital Universitari (Spain), National University of Singapore (Singapore), National University Health System (Singapore), Curtin University (Australia), University of Toronto (Canada), Hospital for Sick Children (Canada), UNSW Sydney (Australia), Centre for Healthy Brain Ageing (Australia), Institut de Recerca Sant Pau (Spain), Singapore National Eye Center (Singapore), Singapore Eye Research Institute (Singapore), Duke-NUS Medical School (Singapore), The University of Texas at San Antonio Health Science Center (United States), Kyoto University (Japan), Center for Genomic Medicine, Graduate School of Medicine, Kyoto University (Japan), Edinburgh Royal Infirmary (United Kingdom), UK Dementia Research Institute (United Kingdom), Kyoto University Hospital (Japan), Harvard University (United States), Shizuoka Graduate University of Public Health (Japan), German Center for Neurodegenerative Diseases (Germany), Tsinghua University (China), The University of Queensland (Australia), Peking Union Medical College Hospital (China), Prince of Wales Hospital (Australia), Université Paris Cité (France), Institut de Psychiatrie et Neurosciences de Paris (France), Centre Hospitalier Universitaire Sainte-Justine (Canada), Université de Montréal (Canada), University Hospital Mútua de Terrassa (Spain), Mútua Terrassa (Spain), Fealinx (France) (France), Institute for Open and Transdisciplinary Research Initiatives (Japan), Center for Infectious Disease Education and Research, The University of Osaka (Japan), Immunology Frontier Research Center, The University of Osaka (Japan), The University of Tokyo (Japan), Neuroscience Research Australia (Australia), Adolfo Ibáñez University (Chile)
Categories: genetics / omics (modality), structural MRI / diffusion (modality), human (organism), stroke (population), cellular / molecular (subfield)

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ncbi.nlm.nih.gov/geo, NCBI

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