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A hybrid pipeline for carotid artery segmentation using YOLOv11n and contour models.

Overview

Authors: Gerges M Salama1, Mohammed Safy2, Dina A Hassanin1,3, Ashraf A M Khalaf1, Mahmoud Khaled Abd-Ellah4
  1. Department of Electrical Engineering, Faculty of Engineering, Minia University, Minia, 61111 Egypt
  2. College of Computing and Information Technology, Arab Academy for Science, Technology and Maritime Transport (AASTMT), Smart Village, Giza, 2401 Egypt
  3. Electrical and Computer Engineering Department, Minia Higher Institute of Engineering and Technology, New El-Minya, Minia Egypt
  4. Faculty of Artificial Intelligence, Egyptian Russian University, Cairo, 11829 Egypt
Journal: Scientific reports, volume 16, issue 1, article 9808
Dates: received 3 November 2025; accepted 17 February 2026; published online 23 March 2026
Type: Research article · Language: English
License: CC BY
Identifiers: DOI 10.1038/s41598-026-41007-2 · PMID 41872242 · PMCID PMC13018575 · OpenAlex W7140075001
Open access: gold, a free copy (OpenAlex)
Categories: other (modality), human (organism), stroke (population), methods / tools (subfield)
Methods: Connectivity, Machine learning
Keywords: Carotid artery, Ultrasound imaging, Segmentation, Deep learning, Active contour, Stroke, Computational biology and bioinformatics, Diseases, Engineering, Neurology, Neuroscience
MeSH: Carotid Arteries*, Carotid Artery Diseases*, Image Processing, Computer-Assisted*, Ultrasonography, Carotid Arteries*, Algorithms, Humans (* major topic)
Topic: Retinal Imaging and Analysis (Radiology, Nuclear Medicine and Imaging, Medicine), according to OpenAlex
Citations: not cited yet (Europe PMC); 61 references in the paper

Abstract

Carotid artery segmentation is critical for determining the degree of vascular disease, and for recommending treatment options. Early detection of carotid atherosclerosis is critical for preventing stroke. Stroke-related brain damage can cause deficits in speech or vision, and large strokes can be fatal. However, automatic segmentation of the carotid artery lumen remains difficult due to the low quality of US images, and the existence of stenosis, jugular veins, and abnormalities in carotid images. This article presents a hybrid pipeline for segmenting both carotid transverse and longitudinal lumens without any user interaction. This hybrid pipeline starts with automatically localizing the carotid artery lumen in the transverse and longitudinal sections via YOLOv11n. Then, a multistage preprocessing framework was applied to the transverse section before its lumen was segmented by the active contour. For the longitudinal section, an automated padded mask was generated to guarantee reliable initialization for Chan-Vese level-set evolution. A paired t test validated the relevance of the proposed modules (p < 0.0001). The proposed multiphase segmentation pipeline achieved a Dice index and accuracy of 94.9% and 97.7%, respectively, for the longitudinal section and 90.8% and 99.6%, respectively, for the transverse section. A comprehensive ablation analysis has shown that numerical stability depends on the YOLOv11n localization phase. The system attained near real-time inference for the carotid transverse section (< 1 s) despite being evaluated on low-end hardware, demonstrating its computational efficiency and promise for clinical integration.

Reproduced under the paper's license (CC BY), from the paper cited above.

Code

The paper links to its data and to no code of its authors: see the Data section.

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Data

Datasets cited

Data availability

The dataset in the manuscript is from public datasets. The data were sourced from two distinct datasets:1. Carotid Transverse Section Dataset: This dataset is publicly available via the Mendeley Data repository (DOI: 10.17632/d4xt63mgjm. (1) and can be accessed directly through the link: https://data.mendeley.com/datasets/d4xt63mgjm/. 2. Carotid Longitudinal Dataset: This dataset is publicly available via the Zenodo Data repository (DOI: 10.5281/zenodo.17552717) and can be accessed directly through the link: 10.5281/zenodo.17552717.

Reproduced under the paper's license (CC BY), from the paper cited above.

Versions

The history of this record: each version stored by the harvester or made by a correction of its authors or of the maintainers of its code, and what changed in its facts. The texts of the paper (its abstract, its availability statements) are not part of it; versions that changed only those are not listed.

Version 1, 30 September 2026: the first record

Recorded: type, language, journal, volume, issue, pages, dates, 5 authors, 11 keywords, 6 MeSH terms, 1 funder, 30 references.

Cite

This paper

Salama, G. M., Safy, M., Hassanin, D. A., Khalaf, A. A. M., & Abd-Ellah, M. K. (2026). A hybrid pipeline for carotid artery segmentation using YOLOv11n and contour models. Scientific reports, 16(1), 9808. https://doi.org/10.1038/s41598-026-41007-2

BibTeX

@article{salama2026hybrid,
author = {Salama, Gerges M and Safy, Mohammed and Hassanin, Dina A and Khalaf, Ashraf A M and Abd-Ellah, Mahmoud Khaled},
title = {{A hybrid pipeline for carotid artery segmentation using YOLOv11n and contour models}},
journal = {Scientific reports},
year = {2026},
month = mar,
volume = {16},
number = {1},
pages = {9808},
publisher = {Nature Publishing Group},
issn = {2045-2322},
doi = {10.1038/s41598-026-41007-2},
url = {https://doi.org/10.1038/s41598-026-41007-2},
pmid = {41872242},
pmcid = {PMC13018575}
}

RIS

TY - JOUR
AU - Salama, Gerges M
AU - Safy, Mohammed
AU - Hassanin, Dina A
AU - Khalaf, Ashraf A M
AU - Abd-Ellah, Mahmoud Khaled
TI - A hybrid pipeline for carotid artery segmentation using YOLOv11n and contour models
T2 - Scientific reports
J2 - Sci Rep
PY - 2026
DA - 2026/03/23
VL - 16
IS - 1
SP - 9808
SN - 2045-2322
PB - Nature Publishing Group
DO - 10.1038/s41598-026-41007-2
UR - https://doi.org/10.1038/s41598-026-41007-2
LA - en
ER -

CSL-JSON

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