OSCR

Genome editing-based refinement of GPCR visualization in mice using the oxytocin receptor as a model.

Overview

Authors: Yukiko U Inoue1, Eon Kurumiya2, Ryosuke Tany2, Eriko Koike1, Junko Asami1, Ikuo Masuho2,3, Takayoshi Inoue1
  1. Department of Biochemistry and Cellular Biology, National Institute of Neuroscience, National Center of Neurology and Psychiatry, Kodaira, 187-8502 Tokyo Japan
  2. Pediatrics and Rare Diseases Group, Sanford Research, Sioux Falls, SD 57104 USA
  3. Department of Pediatrics, Sanford School of Medicine, University of South Dakota, Sioux Falls, SD 57105 USA
Institutions: National Center of Neurology and Psychiatry (Japan); Sanford Research (United States); University of South Dakota (United States)
Journal: Scientific reports, volume 16, issue 1, article 22910
Dates: received 15 October 2025; accepted 24 April 2026; published online 20 May 2026
Type: Research article · Language: English
License: CC BY-NC-ND
Identifiers: DOI 10.1038/s41598-026-50956-7 · PMID 42161997 · PMCID PMC13389537 · OpenAlex W7161808350
Open access: gold, a free copy (OpenAlex)
Status: data only
Categories: human (organism), mouse (organism), cellular / molecular (subfield)
Methods: Statistics, Evoked potentials
Keywords: GPCR, Oxytocin receptor, Epitope tagging, Genome editing, Biological techniques, Biotechnology, Computational biology and bioinformatics, Neuroscience
MeSH: Gene Editing*, Receptors, G-Protein-Coupled*, Receptors, Oxytocin*, Animals, Gene Knock-In Techniques, Humans, Luminescent Proteins, Mice, Neurons (* major topic)
Topic: Neuroendocrine regulation and behavior (Social Psychology, Psychology), according to OpenAlex
Funding: Japan Society for the Promotion of Science (KAKENHI (20K06467, 23K05612)); Intramural Research Grants for Neurological and Psychiatric Disorders of NCNP (3-9, 6-9); Sanford Research
Citations: not cited yet (Europe PMC); 40 references in the paper

Abstract

The abstract is not reproduced here: the paper's license (CC BY-NC-ND) does not allow it. Read it in the paper, at the publisher or on Europe PMC.

Code

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Data

Datasets cited

Data availability statement

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Read it in the paper: doi.org/10.1038/s41598-026-50956-7.

Versions

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Version 1, 28 September 2026: the first record

Recorded: type, language, journal, volume, issue, pages, dates, 7 authors, 8 keywords, 9 MeSH terms, 3 funders, 39 references.

Cite

This paper

Inoue, Y. U., Kurumiya, E., Tany, R., Koike, E., Asami, J., Masuho, I., & Inoue, T. (2026). Genome editing-based refinement of GPCR visualization in mice using the oxytocin receptor as a model. Scientific reports, 16(1), 22910. https://doi.org/10.1038/s41598-026-50956-7

BibTeX

@article{inoue2026genome,
author = {Inoue, Yukiko U and Kurumiya, Eon and Tany, Ryosuke and Koike, Eriko and Asami, Junko and Masuho, Ikuo and Inoue, Takayoshi},
title = {{Genome editing-based refinement of GPCR visualization in mice using the oxytocin receptor as a model}},
journal = {Scientific reports},
year = {2026},
month = may,
volume = {16},
number = {1},
pages = {22910},
publisher = {Nature Publishing Group},
issn = {2045-2322},
doi = {10.1038/s41598-026-50956-7},
url = {https://doi.org/10.1038/s41598-026-50956-7},
pmid = {42161997},
pmcid = {PMC13389537}
}

RIS

TY - JOUR
AU - Inoue, Yukiko U
AU - Kurumiya, Eon
AU - Tany, Ryosuke
AU - Koike, Eriko
AU - Asami, Junko
AU - Masuho, Ikuo
AU - Inoue, Takayoshi
TI - Genome editing-based refinement of GPCR visualization in mice using the oxytocin receptor as a model
T2 - Scientific reports
J2 - Sci Rep
PY - 2026
DA - 2026/05/20
VL - 16
IS - 1
SP - 22910
SN - 2045-2322
PB - Nature Publishing Group
DO - 10.1038/s41598-026-50956-7
UR - https://doi.org/10.1038/s41598-026-50956-7
LA - en
ER -

CSL-JSON

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"ISSN": "2045-2322",
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"language": "en",
"issued": {
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