OSCR

Brain age gradients as intermediate phenotypes linking plasma p-tau217 to cognition in community-dwelling older adults.

Overview

Authors: Nicholas Riccardi1, Ansley Martin1, Dariusz Pytel2, Sarah Newman-Norlund1, Steven L. Carroll2, Chris Rorden3, Julius Fridriksson1, Leonardo Bonilha4
ORCID iDs: Steven L. Carroll
  1. Department of Communication Sciences and Disorders, University of South Carolina,Columbia, SC USA
  2. Department of Pathology and Laboratory Medicine, Medical University of South Carolina,Charleston, SC USA
  3. Department of Psychology, University of South Carolina,Columbia, SC USA
  4. Department of Neurology, University of South Carolina School of Medicine,Columbia, SC USA
Institutions: University of South Carolina (United States); Medical University of South Carolina (United States)
Journal: NPJ dementia, volume 2, issue 1, article 54
Dates: received 6 January 2026; accepted 14 June 2026; published online 8 July 2026; in print 2026
Type: Research article · Language: English
License: CC BY-NC-ND
Identifiers: DOI 10.1038/s44400-026-00115-6 · PMID 42422561 · PMCID PMC13341312 · OpenAlex W7167571940
Open access: hybrid, a free copy (OpenAlex)
Status: code on request
Categories: structural MRI / diffusion (modality), other (modality), human (organism), Alzheimer's / dementia (population)
Methods: Connectivity, Statistics, Preprocessing, Machine learning
Keywords: Biomarkers, Neurology, Neuroscience
Topic: Dementia and Cognitive Impairment Research (Psychiatry and Mental health, Medicine), according to OpenAlex
Funding: Aging Brain Cohort Excellence Initiative (Not Applicable); National Institute on Deafness and Other Communication Disorders (R01DC022458); Alzheimer's Disease Research Center Designation (South Carolina Department of Health and Human Services) (Not Applicable)
Citations: not cited yet (Europe PMC); 66 references in the paper

Abstract

The abstract is not reproduced here: the paper's license (CC BY-NC-ND) does not allow it. Read it in the paper, at the publisher or on Europe PMC.

Code

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Code availability statement

The paper has a code availability statement. Its license (CC BY-NC-ND) does not allow reproducing it here; in short, from what the harvester recognized in it:

  • it says that the code is available on request

Read it in the paper: doi.org/10.1038/s44400-026-00115-6.

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Data

Datasets cited

Data availability statement

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  • no repository, dataset or request procedure was recognized in it

Read it in the paper: doi.org/10.1038/s44400-026-00115-6.

Versions

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Version 2, 28 September 2026

  • Publisher: n/a → Springer Science+Business Media

Version 1, 27 September 2026: the first record

Recorded: type, language, journal, volume, issue, pages, dates, 8 authors, 3 keywords, 3 funders, 62 references.

Cite

This paper

Riccardi, N., Martin, A., Pytel, D., Newman-Norlund, S., Carroll, S. L., Rorden, C., Fridriksson, J., & Bonilha, L. (2026). Brain age gradients as intermediate phenotypes linking plasma p-tau217 to cognition in community-dwelling older adults. NPJ dementia, 2(1), 54. https://doi.org/10.1038/s44400-026-00115-6

BibTeX

@article{riccardi2026brain,
author = {Riccardi, Nicholas and Martin, Ansley and Pytel, Dariusz and Newman-Norlund, Sarah and Carroll, Steven L. and Rorden, Chris and Fridriksson, Julius and Bonilha, Leonardo},
title = {{Brain age gradients as intermediate phenotypes linking plasma p-tau217 to cognition in community-dwelling older adults}},
journal = {NPJ dementia},
year = {2026},
month = jul,
volume = {2},
number = {1},
pages = {54},
publisher = {Springer Science+Business Media},
issn = {3005-1940},
doi = {10.1038/s44400-026-00115-6},
url = {https://doi.org/10.1038/s44400-026-00115-6},
pmid = {42422561},
pmcid = {PMC13341312}
}

RIS

TY - JOUR
AU - Riccardi, Nicholas
AU - Martin, Ansley
AU - Pytel, Dariusz
AU - Newman-Norlund, Sarah
AU - Carroll, Steven L.
AU - Rorden, Chris
AU - Fridriksson, Julius
AU - Bonilha, Leonardo
TI - Brain age gradients as intermediate phenotypes linking plasma p-tau217 to cognition in community-dwelling older adults
T2 - NPJ dementia
J2 - NPJ Dement
PY - 2026
DA - 2026/07/08
VL - 2
IS - 1
SP - 54
SN - 3005-1940
PB - Springer Science+Business Media
DO - 10.1038/s44400-026-00115-6
UR - https://doi.org/10.1038/s44400-026-00115-6
LA - en
ER -

CSL-JSON

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"language": "en",
"issued": {
"date-parts": [
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}

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