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Evaluation of a 0.05 T low-field MRI system for canine brain imaging via comparison with images acquired at 1.5 T field strength: a pilot cadaver study.

Overview

Authors: Elisabeth Maria Burgers1, Samantha Miles1,2, Stefanie Veraa1, Thomas O'Reilly3, Ruben van den Broek3, Chloé Najac3, Beatrice Lena3, Andrew Webb3
  1. Division of Diagnostic Imaging, Department of Clinical Sciences, Utrecht University, Utrecht, the Netherlands
  2. IDEXX Telemedicine Consultants, Department of Radiology, Hoofddorp, the Netherlands
  3. C.J. Gorter MRI Center, Department of Radiology, Leiden University Medical Center, Leiden, the Netherlands
Institutions: Utrecht University (Netherlands); Leiden University Medical Center (Netherlands)
Journal: The veterinary quarterly, volume 46, issue 1, article 2720640
Dates: received 8 July 2025; accepted 13 August 2026; published online 12 September 2026; in print December 2026
Type: Research article · Language: English
License: CC BY
Identifiers: DOI 10.1080/01652176.2026.2720640 · PMID 42730678 · PMCID PMC13573525 · OpenAlex W7212377209
Open access: gold, a free copy (OpenAlex)
Status: data only
Categories: structural MRI / diffusion (modality), other (organism), other condition (population)
Methods: Statistics, Spectral & time-frequency
Keywords: Hydrocephalus, Image Contrast, One Health, Low Field Magnetic Resonance Imaging, Permanent Magnets, Halbach Array, Canine Neuroimaging, Sustainable Imaging
MeSH: Brain*, Magnetic Resonance Imaging*, Neuroimaging*, Animals, Cadaver, Dogs, Feasibility Studies, Hydrocephalus, Pilot Projects (* major topic)
Topic: Cerebrospinal fluid and hydrocephalus (Cellular and Molecular Neuroscience, Neuroscience), according to OpenAlex
Funding: Stichting Bouwstenen voor Dierenwelzijn; Utrecht Universiteitsfonds; European Research Council (101021218, PASMAR 101021218); K.F. Hein Fonds; Triodos Foundation; Dutch Research Council (NWO) (21762); NWO Open Technologie (21762); Abri voor Dieren
Citations: not cited yet (Europe PMC); 47 references in the paper

Abstract

Magnetic resonance imaging (MRI) systems continue to grow in number in veterinary and human medicine with higher field strength magnets increasingly available; however, the associated high costs have created healthcare inequities. This technical feasibility study aimed to evaluate a low-cost, portable, and permanent magnet-based 0.05 T low-field system (LF), originally designed for human neuroimaging, for assessing the canine brain. By using 23 canine cadavers, a scanning protocol was developed, consisting of transverse T1-weighted (T1w) and T2-weighted (T2w) sequences, and compared to a 1.5 T (HF) protocol for the visibility of 22 anatomical features. For the purpose of hydrocephalus evaluation, the LF system showed non-inferior detection of the lateral ventricles (LV) and mesencephalic aqueduct on T2w sequences with >90% conditional probability for detecting these features on the LF, given they were present on the HF. For T1w sequences, the LF system had inconclusive non-inferiority for detection of LV with 76.6% conditional probability. In summary, a canine brain scanning protocol was successfully developed for a 0.05 T MRI with preliminary evaluation suggestive that this device can aid with the detection of hydrocephalus. Future in vivo studies are required to evaluate the device's true clinical application.

Reproduced under the paper's license (CC BY), from the paper cited above.

Code

The paper links to its data, not to its authors' code: see the Data section.

Tracing map

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Data

Datasets cited

Data availability statement

The low-field data supporting the findings of this study are openly available in Zenodo at https://doi.org/10.5281/zenodo.18873835, reference number 18873835.

Reproduced under the paper's license (CC BY), from the paper cited above.

Versions

The history of this record: each version stored by the harvester or made by a correction of its authors or of the maintainers of its code, and what changed in its facts. The texts of the paper (its abstract, its availability statements) are not part of it; versions that changed only those are not listed.

Version 1, 27 September 2026: the first record

Recorded: type, language, journal, volume, issue, pages, dates, 8 authors, 8 keywords, 9 MeSH terms, 8 funders, 44 references.

Cite

This paper

Burgers, E. M., Miles, S., Veraa, S., O'Reilly, T., van den Broek, R., Najac, C., Lena, B., & Webb, A. (2026). Evaluation of a 0.05 T low-field MRI system for canine brain imaging via comparison with images acquired at 1.5 T field strength: a pilot cadaver study. The veterinary quarterly, 46(1), 2720640. https://doi.org/10.1080/01652176.2026.2720640

BibTeX

@article{burgers2026evaluation,
author = {Burgers, Elisabeth Maria and Miles, Samantha and Veraa, Stefanie and O'Reilly, Thomas and van den Broek, Ruben and Najac, Chloé and Lena, Beatrice and Webb, Andrew},
title = {{Evaluation of a 0.05 T low-field MRI system for canine brain imaging via comparison with images acquired at 1.5 T field strength: a pilot cadaver study}},
journal = {The veterinary quarterly},
year = {2026},
month = sep,
volume = {46},
number = {1},
pages = {2720640},
publisher = {Taylor \& Francis},
issn = {0165-2176},
doi = {10.1080/01652176.2026.2720640},
url = {https://doi.org/10.1080/01652176.2026.2720640},
pmid = {42730678},
pmcid = {PMC13573525}
}

RIS

TY - JOUR
AU - Burgers, Elisabeth Maria
AU - Miles, Samantha
AU - Veraa, Stefanie
AU - O'Reilly, Thomas
AU - van den Broek, Ruben
AU - Najac, Chloé
AU - Lena, Beatrice
AU - Webb, Andrew
TI - Evaluation of a 0.05 T low-field MRI system for canine brain imaging via comparison with images acquired at 1.5 T field strength: a pilot cadaver study
T2 - The veterinary quarterly
J2 - Vet Q
PY - 2026
DA - 2026/09/12
VL - 46
IS - 1
SP - 2720640
SN - 0165-2176
PB - Taylor & Francis
DO - 10.1080/01652176.2026.2720640
UR - https://doi.org/10.1080/01652176.2026.2720640
LA - en
ER -

CSL-JSON

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