OSCR

Health system patterns of imaging and fluid biomarker testing in the era of anti-amyloid therapies.

Overview

Authors: W Hudson Robb1, Gurkiran Kaur1, Steven Huang1, Felipe Martinez1, Ba Nguyen1, Clifford H Shin1, Ming Yang1, Christopher T Conyers2, Christopher B Grilli2, David P Upjohn2, Victor E Ortega2, Timothy J Hohman3,4, Richard M Keegan5, Ephraim E Parent6, Petrice M Cogswell7, Jonathan Graff‐Radford8, Derek R Johnson7, Vijay K Ramanan8, Mary Ellen Koran1
ORCID iDs: W Hudson Robb, Mary Ellen Koran
  1. Department of Radiology, Mayo Clinic Arizona, Phoenix, Arizona, USA
  2. Center for Individualized Medicine, Mayo Clinic, Scottsdale, Arizona, USA
  3. Vanderbilt Memory and Alzheimer's Center, Vanderbilt University School of Medicine, Nashville, Tennessee, USA
  4. Department of Neurology, Vanderbilt University Medical Center, Nashville, Tennessee, USA
  5. Life Molecular Imaging, Boston, Massachusetts, USA
  6. Department of Radiology, Mayo Clinic Jacksonville, Jacksonville, Florida, USA
  7. Department of Radiology, Mayo Clinic Rochester, Rochester, Minnesota, USA
  8. Department of Neurology, Mayo Clinic Rochester, Rochester, Minnesota, USA
Institutions: Mayo Clinic in Arizona (United States); Mayo Clinic Hospital (United States); Mayo Clinic (United States); Vanderbilt University (United States); Vanderbilt University Medical Center (United States); Mayo Clinic in Florida (United States)
Journal: Alzheimer's & dementia : the journal of the Alzheimer's Association, volume 22, issue 4, article e71343
Dates: received 17 November 2025; accepted 10 March 2026; published online 8 April 2026; in print April 2026
Type: Research article · Language: English
License: CC BY-NC-ND
Identifiers: DOI 10.1002/alz.71343 · PMID 41950049 · PMCID PMC13060759 · OpenAlex W7152001082
Open access: hybrid, a free copy (OpenAlex)
Status: dead link
Categories: other (modality), PET / SPECT (modality), human (organism), Alzheimer's / dementia (population), clinical / translational (subfield)
Methods: Machine learning, Statistics
Keywords: Alzheimer's disease, amyloid PET, anti‐amyloid therapy, biomarkers, lecanemab, plasma p‐tau217, sex differences
MeSH: Alzheimer Disease*, Amyloid beta-Peptides*, Aged, Aged, 80 and over, Apolipoproteins E, Biomarkers, Brain, Electronic Health Records, Female, Humans, Male, Positron-Emission Tomography, Retrospective Studies, tau Proteins (* major topic)
Topic: Dementia and Cognitive Impairment Research (Psychiatry and Mental health, Medicine), according to OpenAlex
Funding: NIA NIH HHS (K76AG088554); National Institute on Aging (K76AG088554); Alzheimer's Association Clinician Scientist Fellowship (MEK)
Citations: not cited yet (Europe PMC); 25 references in the paper

Abstract

The abstract is not reproduced here: the paper's license (CC BY-NC-ND) does not allow it. Read it in the paper, at the publisher or on Europe PMC.

Code

No file of the authors' code could be read here: it is described below, and read at its source.

RadGenLab/AmyloidVolume

License: none: the authors keep all their rights
State: the link is dead, verified on 28 September 2026
Evidence: found in the paper
Software Heritage: not archived
Found in: the text, “Aβ PET positivity”
Not found: README, license file, CITATION.cff, environment file, tests, continuous integration, documentation
Availability: 1 check, the latest on 28 September 2026: the link is dead
  • 28 September 2026: the link is dead
At the source: github.com/RadGenLab/AmyloidVolume

Tracing map

Proposed by the machine: these links were found in the paper and verified at the source, without human review. The map will receive a Zenodo DOI once one of the paper's authors has validated it with their ORCID.

What the map holds:

  • 1 repository of the authors' code, each at its verified commit, with its license and how the link was found in the paper;
  • 0 scripts, each with its path and the digest of its content;
  • no match between paragraphs and code yet;
  • neither the text of the paper nor the code itself.

Its JSON (tracing-map.json) is deposited on Zenodo with its DOI once the map is validated.

Data

No dataset and no data link were found in the paper.

Versions

The history of this record: each version stored by the harvester or made by a correction of its authors or of the maintainers of its code, and what changed in its facts. The texts of the paper (its abstract, its availability statements) are not part of it; versions that changed only those are not listed.

Version 1, 28 September 2026: the first record

Recorded: type, language, journal, volume, issue, pages, dates, 19 authors, 7 keywords, 14 MeSH terms, 3 funders, 23 references.

Cite

This paper

Robb, W. H., Kaur, G., Huang, S., Martinez, F., Nguyen, B., Shin, C. H., Yang, M., Conyers, C. T., Grilli, C. B., Upjohn, D. P., Ortega, V. E., Hohman, T. J., Keegan, R. M., Parent, E. E., Cogswell, P. M., Graff‐Radford, J., Johnson, D. R., Ramanan, V. K., & Koran, M. E. (2026). Health system patterns of imaging and fluid biomarker testing in the era of anti-amyloid therapies. Alzheimer's & dementia : the journal of the Alzheimer's Association, 22(4), e71343. https://doi.org/10.1002/alz.71343

BibTeX

@article{robb2026health,
author = {Robb, W Hudson and Kaur, Gurkiran and Huang, Steven and Martinez, Felipe and Nguyen, Ba and Shin, Clifford H and Yang, Ming and Conyers, Christopher T and Grilli, Christopher B and Upjohn, David P and Ortega, Victor E and Hohman, Timothy J and Keegan, Richard M and Parent, Ephraim E and Cogswell, Petrice M and Graff‐Radford, Jonathan and Johnson, Derek R and Ramanan, Vijay K and Koran, Mary Ellen},
title = {{Health system patterns of imaging and fluid biomarker testing in the era of anti-amyloid therapies}},
journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association},
year = {2026},
month = apr,
volume = {22},
number = {4},
pages = {e71343},
publisher = {Wiley},
issn = {1552-5260},
doi = {10.1002/alz.71343},
url = {https://doi.org/10.1002/alz.71343},
pmid = {41950049},
pmcid = {PMC13060759}
}

RIS

TY - JOUR
AU - Robb, W Hudson
AU - Kaur, Gurkiran
AU - Huang, Steven
AU - Martinez, Felipe
AU - Nguyen, Ba
AU - Shin, Clifford H
AU - Yang, Ming
AU - Conyers, Christopher T
AU - Grilli, Christopher B
AU - Upjohn, David P
AU - Ortega, Victor E
AU - Hohman, Timothy J
AU - Keegan, Richard M
AU - Parent, Ephraim E
AU - Cogswell, Petrice M
AU - Graff‐Radford, Jonathan
AU - Johnson, Derek R
AU - Ramanan, Vijay K
AU - Koran, Mary Ellen
TI - Health system patterns of imaging and fluid biomarker testing in the era of anti-amyloid therapies
T2 - Alzheimer's & dementia : the journal of the Alzheimer's Association
J2 - Alzheimers Dement
PY - 2026
DA - 2026/04/01
VL - 22
IS - 4
SP - e71343
SN - 1552-5260
PB - Wiley
DO - 10.1002/alz.71343
UR - https://doi.org/10.1002/alz.71343
LA - en
ER -

CSL-JSON

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The tracing map gets a citation of its own once an author has validated it and it has a DOI.

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