OSCR

Common cause versus dynamic mutualism: Insights into ADHD's common comorbidities.

Overview

  1. Department of Psychological Sciences, Vanderbilt University, Nashville, Tennessee, USA
Institutions: Vanderbilt University (United States)
Journal: JCPP advances, article e70142
Dates: received 12 September 2025; accepted 29 May 2026; published online 18 June 2026; in print June 2026
Type: Research article · Language: English
License: CC BY
Identifiers: DOI 10.1002/jcv2.70142 · PMID 42416609 · PMCID PMC13339281 · OpenAlex W7165136574
Open access: gold, a free copy (OpenAlex)
Status: code verified
Categories: ADHD (population), developmental (subfield)
Methods: Statistics
Keywords: ADHD classification, common cause model, comorbidity, dynamic mutualism, externalizing spectrum, neurodevelopmental spectrum
Topic: Attention Deficit Hyperactivity Disorder (Psychiatry and Mental health, Medicine), according to OpenAlex
Funding: NIDA NIH HHS (U01 DA041148, U01 DA050988, U01 DA051016, U01 DA041089, U24 DA041147, U01 DA041022, U01 DA041025, U01 DA041174, U01 DA050989, U01 DA041134, U01 DA050987, U01 DA051039, U01 DA041120, U01 DA041028, U01 DA041106, U01 DA041156, U01 DA041048, U01 DA041093, U01 DA041117, U01 DA051018, U01 DA051037, U01 DA051038, U24 DA041123); National Institute on Alcohol Abuse and Alcoholism (R00AA028306); NIAAA NIH HHS (R00 AA028306)
Citations: cited by 2 papers (Europe PMC); 125 references in the paper

Abstract

Background: Contemporary classification systems differ in their conceptualization of ADHD as either an externalizing or neurodevelopmental condition, with both perspectives promoting the common cause model as an explanation of ADHD's comorbidity. An alternative theory, dynamic mutualism, proposes that ADHD's comorbidity emerges through reciprocal interactions among symptoms over time, as opposed to a common cause.

Methods: We tested the common cause and the dynamic mutualism theories in explaining the associations between aspects of ADHD (i.e., ADHD, inattention, hyperactivity/impulsivity, cognitive disengagement) and the neurodevelopmental and externalizing spectra across four waves of the Adolescent Brain Cognitive Development (ABCD) Study data (n = 11,878 youths aged 9–10 at baseline; 48% female).

Results: Results largely supported the common cause theory in explaining the developmental links between ADHD and both the externalizing and neurodevelopmental spectra. Findings varied across ADHD subdimensions, although not substantially, with hyperactivity/impulsivity more closely linked to the externalizing spectrum and cognitive disengagement more closely linked to the neurodevelopmental spectrum.

Conclusion: ADHD is best conceptualized as a disorder that bridges both the externalizing and neurodevelopmental domains, rather than fitting exclusively within either category. Given the assessment structure of the ABCD Study, there was more support for the common cause model compared with dynamic mutualism.

Reproduced under the paper's license (CC BY), from the paper cited above.

Code

No file of the authors' code could be read here: it is described below, and read at its source.

OSF vf2as

License: none: the authors keep all their rights
State: the link answers, verified on 27 September 2026
Evidence: files inventoried
Size: 7 files
Software Heritage: not checked
Found in: the acknowledgements
Not found: README, license file, CITATION.cff, environment file, tests, continuous integration, documentation
Availability: 1 check, the latest on 27 September 2026: the link answers (HTTP 200)
  • 27 September 2026: the link answers (HTTP 200)
At the source: osf.io/vf2as/

OSF n7uka

License: none: the authors keep all their rights
State: the link answers, verified on 27 September 2026
Evidence: files inventoried
Size: 3 files, 0 scripts
Software Heritage: not checked
Found in: the references
Not found: README, license file, CITATION.cff, environment file, tests, continuous integration, documentation
Availability: 1 check, the latest on 27 September 2026: the link answers (HTTP 200)
  • 27 September 2026: the link answers (HTTP 200)
At the source: osf.io/n7uka

Tracing map

Proposed by the machine: these links were found in the paper and verified at the source, without human review. The map will receive a Zenodo DOI once one of the paper's authors has validated it with their ORCID.

What the map holds:

  • 2 repositories of the authors' code, each at its verified commit, with its license and how the link was found in the paper;
  • 0 scripts, each with its path and the digest of its content;
  • no match between paragraphs and code yet;
  • neither the text of the paper nor the code itself.

Its JSON (tracing-map.json) is deposited on Zenodo with its DOI once the map is validated.

Data

No dataset and no data link were found in the paper.

Data availability statement

The data that support the findings of this study are openly available in NIH Brain Development Cohorts (NBDC) Data Hub at https://www.nbdc‐datahub.org (https://www.nbdc-datahub.org), reference number 10.15154/8873‐zj65.

Reproduced under the paper's license (CC BY), from the paper cited above.

Versions

The history of this record: each version stored by the harvester or made by a correction of its authors or of the maintainers of its code, and what changed in its facts. The texts of the paper (its abstract, its availability statements) are not part of it; versions that changed only those are not listed.

Version 1, 27 September 2026: the first record

Recorded: type, language, journal, pages, dates, 2 authors, 6 keywords, 3 funders, 118 references.

Cite

This paper

Peng, Z., & Watts, A. L. (2026). Common cause versus dynamic mutualism: Insights into ADHD's common comorbidities. JCPP advances, e70142. https://doi.org/10.1002/jcv2.70142

BibTeX

@article{peng2026common,
author = {Peng, Zheyue and Watts, Ashley L},
title = {{Common cause versus dynamic mutualism: Insights into ADHD's common comorbidities}},
journal = {JCPP advances},
year = {2026},
month = jun,
pages = {e70142},
publisher = {Wiley},
issn = {2692-9384},
doi = {10.1002/jcv2.70142},
url = {https://doi.org/10.1002/jcv2.70142},
pmid = {42416609},
pmcid = {PMC13339281}
}

RIS

TY - JOUR
AU - Peng, Zheyue
AU - Watts, Ashley L
TI - Common cause versus dynamic mutualism: Insights into ADHD's common comorbidities
T2 - JCPP advances
J2 - JCPP Adv
PY - 2026
DA - 2026/06/18
SP - e70142
SN - 2692-9384
PB - Wiley
DO - 10.1002/jcv2.70142
UR - https://doi.org/10.1002/jcv2.70142
LA - en
ER -

CSL-JSON

{
"id": "10.1002/jcv2.70142",
"type": "article-journal",
"title": "Common cause versus dynamic mutualism: Insights into ADHD's common comorbidities",
"container-title": "JCPP advances",
"author": [
{
"family": "Peng",
"given": "Zheyue"
},
{
"family": "Watts",
"given": "Ashley L"
}
],
"container-title-short": "JCPP Adv",
"page": "e70142",
"DOI": "10.1002/jcv2.70142",
"PMID": "42416609",
"PMCID": "PMC13339281",
"ISSN": "2692-9384",
"publisher": "Wiley",
"URL": "https://doi.org/10.1002/jcv2.70142",
"language": "en",
"issued": {
"date-parts": [
[
2026,
6,
18
]
]
}
}

The tracing map gets a citation of its own once an author has validated it and it has a DOI.

Similar papers

The papers with a page that share the most with this one: the tools found in their code, their categories, datasets, cited references and authors, the rarest counting most.

[1] doi:10.1002/jcv2.70135 [code]
Alterations in resting-state functional connectivity relate to psychopathology trajectories during emerging adolescence.
Journal: JCPP advances
In common: developmental, 4 references
[2] doi:10.1002/pchj.70113
Shared and Unique Patterns of Dysregulated Dual Systems Between Adolescent Problematic Video Gaming and ADHD.
Journal: PsyCh journal
In common: ADHD, developmental, 2 references
[3] doi:10.1038/s41398-026-04121-3
The sex-specific role of adrenal androgens in youth psychopathology.
Journal: Translational psychiatry
In common: developmental, 2 references
[4] doi:10.3390/genes17080849
Deciphering the Role of LNX2 as a Potential Contributor to Neurodevelopmental Disorders.
Journal: Genes
In common: ADHD, developmental, 1 reference
[5] doi:10.1111/desc.70186
The Genetic Origin of Uneven Cognitive Profiles in Heritable Neurodevelopmental Conditions and Individual Differences: Computational Investigations.
Journal: Developmental science
In common: ADHD, developmental, 1 reference
[6] doi:10.2196/84707 [code]
Wireless Electroencephalography in Research on Children With Developmental Disabilities: Scoping Review.
Journal: Journal of medical Internet research
In common: ADHD, developmental, 1 reference
[7] doi:10.1038/s41540-026-00699-y [code]
Inferring relationships among major psychiatric disorders in a resting-state functional connectivity-informed embedding space.
Journal: NPJ systems biology and applications
In common: 2 references
[8] doi:10.1371/journal.pone.0347582 [code]
The longitudinal relation between adolescents' learning outcomes and internalizing symptoms: The role of ADHD symptoms.
Journal: PloS one
In common: ADHD, developmental, 1 reference
[9] doi:10.1038/s41398-026-04080-9 [code]
Altered flow of information in attention-deficit/hyperactivity disorder.
Journal: Translational psychiatry
In common: ADHD, 1 reference
[10] doi:10.1016/j.dcn.2026.101791 [code]
Age-related differences in hippocampal network engagement during safety processing in adolescents.
Journal: Developmental cognitive neuroscience
In common: developmental, 1 reference

Contribute

The authors of this paper can claim it, correct its record and validate its tracing map, and the maintainers of its code (its owner, or a public member of its organization) correct what it says of their repository; anyone signed in can ask for its removal. Every request goes to OSCR's own machine, which answers it; your account page follows them.

Sign in with ORCID to claim this paper as one of its authors, correct its record or validate its tracing map: when the paper's metadata lists your ORCID iD, you are recognized at once. Maintainers of its code: sign in with GitHub, then claim the repository on your account page.

Request its removal

To ask OSCR to remove this record, the copies of its authors' scripts or its tracing map, use the removal request page: signed in, you say who you are, what to remove and why, then review and confirm the request. Published rules decide every request (how).

Discussion, reproductions, activity

Discussion: questions and error reports about this paper and its code, from signed-in readers and its authors. It opens with sign-in.

Reproductions: reports from readers who ran the authors' code: what they reproduced, with which environment, commit and data. It opens with sign-in.

Activity: what happens around this paper: new versions of its record, its map's validation, discussions and reproductions. It opens with sign-in.