OSCR

Timing of device-aided therapy initiation in Parkinson's disease: reference estimates for healthcare planning and biological heterogeneity.

Overview

Authors: David Ledingham1,2,3,4, Charlotte B Stewart1,3,4, Sahana Sathyanarayana1,3,4, Victoria Foster1, Robyn Iredale1, Debra Galley1, Mark R Baker2,3,4, Nicola Pavese1,2,3,5,4
ORCID iDs: Nicola Pavese
  1. Clinical Ageing Research Unit, Newcastle University, Campus for Ageing and Vitality, Newcastle upon Tyne, United Kingdom
  2. Neurosciences, Newcastle Upon Tyne NHS Foundation Trust, Newcastle Upon Tyne, United Kingdom
  3. Translational and Clinical Research Institute, The Medical School, Newcastle University, Newcastle Upon Tyne, United Kingdom
  4. NIHR Newcastle Biomedical Research Centre (BRC), Newcastle upon Tyne, UK
  5. Department of Nuclear Medicine and PET Centre, Aarhus University Hospital, Aarhus, Denmark
Institutions: NIHR Newcastle Biomedical Research Centre (United Kingdom); Newcastle University (United Kingdom); Aarhus University Hospital (Denmark)
Journal: Clinical parkinsonism & related disorders, volume 14, article 100458
Dates: received 2 March 2026; accepted 27 May 2026; published online 4 June 2026
Type: Research article · Language: English
License: CC BY-NC-ND
Identifiers: DOI 10.1016/j.prdoa.2026.100458 · PMID 42292968 · PMCID PMC13263755 · OpenAlex W7163507055
Open access: gold, a free copy (OpenAlex)
Status: data only
Categories: human (organism), Parkinson's (population), clinical / translational (subfield)
Methods: Statistics
Keywords: Parkinson's disease, Device-aided therapy, Deep brain stimulation, Survival analysis, Biomarkers, LRRK2, GBA
Topic: Parkinson's Disease Mechanisms and Treatments (Neurology, Medicine), according to OpenAlex
Citations: not cited yet (Europe PMC); 32 references in the paper
Research resources: RRID:SCR_006431

Abstract

The abstract is not reproduced here: the paper's license (CC BY-NC-ND) does not allow it. Read it in the paper, at the publisher or on Europe PMC.

Code

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Data

Datasets cited

Data availability statement

The paper has a data availability statement. Its license (CC BY-NC-ND) does not allow reproducing it here; in short, from what the harvester recognized in it:

Read it in the paper: doi.org/10.1016/j.prdoa.2026.100458.

Versions

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Version 1, 27 September 2026: the first record

Recorded: type, language, journal, volume, pages, dates, 8 authors, 7 keywords, 32 references, 1 RRID.

Cite

This paper

Ledingham, D., Stewart, C. B., Sathyanarayana, S., Foster, V., Iredale, R., Galley, D., Baker, M. R., & Pavese, N. (2026). Timing of device-aided therapy initiation in Parkinson's disease: reference estimates for healthcare planning and biological heterogeneity. Clinical parkinsonism & related disorders, 14, 100458. https://doi.org/10.1016/j.prdoa.2026.100458

BibTeX

@article{ledingham2026timing,
author = {Ledingham, David and Stewart, Charlotte B and Sathyanarayana, Sahana and Foster, Victoria and Iredale, Robyn and Galley, Debra and Baker, Mark R and Pavese, Nicola},
title = {{Timing of device-aided therapy initiation in Parkinson's disease: reference estimates for healthcare planning and biological heterogeneity}},
journal = {Clinical parkinsonism \& related disorders},
year = {2026},
month = jun,
volume = {14},
pages = {100458},
publisher = {Elsevier},
issn = {2590-1125},
doi = {10.1016/j.prdoa.2026.100458},
url = {https://doi.org/10.1016/j.prdoa.2026.100458},
pmid = {42292968},
pmcid = {PMC13263755}
}

RIS

TY - JOUR
AU - Ledingham, David
AU - Stewart, Charlotte B
AU - Sathyanarayana, Sahana
AU - Foster, Victoria
AU - Iredale, Robyn
AU - Galley, Debra
AU - Baker, Mark R
AU - Pavese, Nicola
TI - Timing of device-aided therapy initiation in Parkinson's disease: reference estimates for healthcare planning and biological heterogeneity
T2 - Clinical parkinsonism & related disorders
J2 - Clin Park Relat Disord
PY - 2026
DA - 2026/06/04
VL - 14
SP - 100458
SN - 2590-1125
PB - Elsevier
DO - 10.1016/j.prdoa.2026.100458
UR - https://doi.org/10.1016/j.prdoa.2026.100458
LA - en
ER -

CSL-JSON

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"title": "Timing of device-aided therapy initiation in Parkinson's disease: reference estimates for healthcare planning and biological heterogeneity",
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"author": [
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"family": "Ledingham",
"given": "David"
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{
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"container-title-short": "Clin Park Relat Disord",
"volume": "14",
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"DOI": "10.1016/j.prdoa.2026.100458",
"PMID": "42292968",
"PMCID": "PMC13263755",
"ISSN": "2590-1125",
"publisher": "Elsevier",
"URL": "https://doi.org/10.1016/j.prdoa.2026.100458",
"language": "en",
"issued": {
"date-parts": [
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}

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