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Differential Progression of Neuroinflammation in Patients with Isolated Rapid-Eye-Movement Sleep Behavior Disorder.

Overview

Authors: Andreas Myhre Baun1, Alex Iranzo2,3,4, Miriam Højholt Terkelsen1,5, Rainer Hinz6, Morten Gersel Stokholm1, Kristian Stær5, Mónica Serradel2,4, Marit Otto7, Kristina Bacher Svendsen5, Alicia Garrido3,8, Dolores Vilas8, Arne Møller9, Carles Gaig2,3,4, Eduardo Tolosa3,8, David J Brooks1,10, Per Borghammer1,11, Simon Fristed Eskildsen9, Nicola Pavese1,10
ORCID iDs: Andreas Myhre Baun, Alex Iranzo, Miriam Højholt Terkelsen, Rainer Hinz, Kristian Stær, Marit Otto, Dolores Vilas, Arne Møller, David J Brooks, Per Borghammer, Simon Fristed Eskildsen, Nicola Pavese
  1. Department of Nuclear Medicine, Aarhus University Hospital, Aarhus, Denmark
  2. Department of Neurology, Hospital Clínic de Barcelona, Barcelona, Spain
  3. Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED), Hospital Clínic, IDIBAPS, Universitat de Barcelona, Barcelona, Spain
  4. Multidisciplinary Sleep Unit, Hospital Clinic de Barcelona, Barcelona, Spain
  5. Department of Neurology, Aarhus University Hospital, Aarhus, Denmark
  6. Wolfson Molecular Imaging Centre, University of Manchester, Manchester, United Kingdom
  7. Department of Clinical Neurophysiology, Aarhus University Hospital, Aarhus, Denmark
  8. Parkinson Disease and Movement Disorders Unit, Neurology Service, Hospital Clínic de Barcelona, Barcelona, Spain
  9. Department of Clinical Medicine, Center of Functionally Integrative Neuroscience, Aarhus University, Aarhus, Denmark
  10. Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, United Kingdom
  11. Lundbeck Foundation Parkinson's Disease Research Center, Aarhus University, Aarhus, Denmark
Institutions: Aarhus University Hospital (Denmark); Biomedical Research Networking Center on Neurodegenerative Diseases (Spain); Hospital Clínic de Barcelona (Spain); Consorci Institut D'Investigacions Biomediques August Pi I Sunyer (Spain); Universitat de Barcelona (Spain); University of Manchester (United Kingdom); Aarhus University (Denmark); Newcastle University (United Kingdom); Lundbeck Foundation (Denmark)
Journal: Movement disorders : official journal of the Movement Disorder Society, volume 41, issue 7, pages 1893-1898
Dates: received 17 December 2025; accepted 18 February 2026; published online 12 March 2026; in print July 2026
Type: Brief report · Language: English
License: CC BY-NC-ND
Identifiers: DOI 10.1002/mds.70265 · PMID 41819824 · PMCID PMC13387925 · OpenAlex W7135076286
Open access: hybrid, a free copy (OpenAlex)
Status: code verified
Categories: PET / SPECT (modality), human (organism), Alzheimer's / dementia (population), Parkinson's (population), sleep disorders (population), cellular / molecular (subfield)
Methods: Statistics
Keywords: Neuroinflammation, Parkinson's, positron emission tomography (PET), Rapid‐eye‐movement (REM) sleep behavior disorder
MeSH: Lewy Body Disease*, Neuroinflammatory Diseases*, Parkinson Disease*, REM Sleep Behavior Disorder*, Aged, Aged, 80 and over, Disease Progression, Female, Humans, Isoquinolines, Male, Middle Aged, Positron-Emission Tomography (* major topic)
Topic: Sleep and Wakefulness Research (Cognitive Neuroscience, Neuroscience), according to OpenAlex
Funding: Danmarks Frie Forskningsfond (4004-00480B, 8020‐00260B, 8020-00260B, 4004‐00480B); Danish Parkinson's Association (R4-A104-B60); Instituto de Salud Carlos III (CB06/05/0018)
Citations: not cited yet (Europe PMC); 38 references in the paper

Abstract

The abstract is not reproduced here: the paper's license (CC BY-NC-ND) does not allow it. Read it in the paper, at the publisher or on Europe PMC.

Code

No file of the authors' code could be read here: it is described below, and read at its source.

lassemadsen

License: none: the authors keep all their rights
State: the link answers, verified on 30 September 2026
Evidence: the link answers
Software Heritage: not checked
Found in: “Data Availability Statement”
Not found: README, license file, CITATION.cff, environment file, tests, continuous integration, documentation
Availability: 1 check, the latest on 30 September 2026: the link answers (HTTP 200)
  • 30 September 2026: the link answers (HTTP 200)
At the source: github.com/lassemadsen

The paper's code and data availability statement is in the Data section.

Tracing map

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Its JSON (tracing-map.json) is deposited on Zenodo with its DOI once the map is validated.

Data

No dataset and no data link were found in the paper.

Code and data availability statement

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Read it in the paper: doi.org/10.1002/mds.70265.

Versions

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Version 1, 30 September 2026: the first record

Recorded: type, language, journal, volume, issue, pages, dates, 18 authors, 4 keywords, 13 MeSH terms, 3 funders, 37 references.

Cite

This paper

Baun, A. M., Iranzo, A., Terkelsen, M. H., Hinz, R., Stokholm, M. G., Stær, K., Serradel, M., Otto, M., Svendsen, K. B., Garrido, A., Vilas, D., Møller, A., Gaig, C., Tolosa, E., Brooks, D. J., Borghammer, P., Eskildsen, S. F., & Pavese, N. (2026). Differential Progression of Neuroinflammation in Patients with Isolated Rapid-Eye-Movement Sleep Behavior Disorder. Movement disorders : official journal of the Movement Disorder Society, 41(7), 1893-1898. https://doi.org/10.1002/mds.70265

BibTeX

@article{baun2026differential,
author = {Baun, Andreas Myhre and Iranzo, Alex and Terkelsen, Miriam Højholt and Hinz, Rainer and Stokholm, Morten Gersel and Stær, Kristian and Serradel, Mónica and Otto, Marit and Svendsen, Kristina Bacher and Garrido, Alicia and Vilas, Dolores and Møller, Arne and Gaig, Carles and Tolosa, Eduardo and Brooks, David J and Borghammer, Per and Eskildsen, Simon Fristed and Pavese, Nicola},
title = {{Differential Progression of Neuroinflammation in Patients with Isolated Rapid-Eye-Movement Sleep Behavior Disorder}},
journal = {Movement disorders : official journal of the Movement Disorder Society},
year = {2026},
month = mar,
volume = {41},
number = {7},
pages = {1893--1898},
publisher = {Wiley},
issn = {0885-3185},
doi = {10.1002/mds.70265},
url = {https://doi.org/10.1002/mds.70265},
pmid = {41819824},
pmcid = {PMC13387925}
}

RIS

TY - JOUR
AU - Baun, Andreas Myhre
AU - Iranzo, Alex
AU - Terkelsen, Miriam Højholt
AU - Hinz, Rainer
AU - Stokholm, Morten Gersel
AU - Stær, Kristian
AU - Serradel, Mónica
AU - Otto, Marit
AU - Svendsen, Kristina Bacher
AU - Garrido, Alicia
AU - Vilas, Dolores
AU - Møller, Arne
AU - Gaig, Carles
AU - Tolosa, Eduardo
AU - Brooks, David J
AU - Borghammer, Per
AU - Eskildsen, Simon Fristed
AU - Pavese, Nicola
TI - Differential Progression of Neuroinflammation in Patients with Isolated Rapid-Eye-Movement Sleep Behavior Disorder
T2 - Movement disorders : official journal of the Movement Disorder Society
J2 - Mov Disord
PY - 2026
DA - 2026/03/12
VL - 41
IS - 7
SP - 1893
EP - 1898
SN - 0885-3185
PB - Wiley
DO - 10.1002/mds.70265
UR - https://doi.org/10.1002/mds.70265
LA - en
ER -

CSL-JSON

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