Histological grade 2 and non-contrast-enhancing phenotype provide prognostic information complementary to DNA methylation classification in TERTp-mutant molecular glioblastomas.
Overview
- Department of Neurosurgery, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan
- School of Medicine, Kumamoto University, Kumamoto, Japan
- Department of Diagnostic Pathology, Kumamoto University Hospital, Kumamoto, Japan
- Department of Cell Pathology, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan
- Department of Molecular Brain Science, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan
Abstract
Glioblastoma (GBM), IDH-wildtype, is the most common and aggressive primary brain tumor in adults. According to the 2021 WHO classification, IDH-wildtype diffuse gliomas with a TERT promoter (TERTp) mutation, EGFR amplification, or combined whole-chromosome 7 gain and 10 loss (+ 7/
Supplementary Information: The online version contains supplementary material available at 10.1186/
Reproduced under the paper's license (CC BY), from the paper cited above.
Code
The paper links to its data, not to its authors' code: see the Data section.
Tracing map
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Data
Datasets cited
- figshare:31986307, at figshare; found in DataCite
- geo:GSE109381, at NCBI GEO; found in the text, “DNA methylation profiling and t-distributed…”
Data availability
The datasets generated and/
Reproduced under the paper's license (CC BY), from the paper cited above.
Versions
The history of this record: each version stored by the harvester or made by a correction of its authors or of the maintainers of its code, and what changed in its facts. The texts of the paper (its abstract, its availability statements) are not part of it; versions that changed only those are not listed.
Version 1, 30 September 2026: the first record
Recorded: type, language, journal, volume, issue, pages, dates, 13 authors, 5 keywords, 16 MeSH terms, 1 funder, 44 references, 7 RRIDs.
Cite
This paper
Sueyoshi, H., Fujimoto, K., Fujita, K., Tanaka, K., Inoue, H., Yamada, R., Yamamoto, T., Nakachi, Y., Kuroda, J.-i., Shinojima, N., Iwamoto, K., Mikami, Y., & Mukasa, A. (2026). Histological grade 2 and non-contrast-enhancing phenotype provide prognostic information complementary to DNA methylation classification in TERTp-mutant molecular glioblastomas. Acta neuropathologica communications, 14(1), 88. https://
BibTeX
@article{sueyoshi2026his
author = {Sueyoshi, Hiroyuki and Fujimoto, Kenji and Fujita, Katsumi and Tanaka, Kazuhito and Inoue, Hirotaka and Yamada, Rin and Yamamoto, Takahiro and Nakachi, Yutaka and Kuroda, Jun-ichiro and Shinojima, Naoki and Iwamoto, Kazuya and Mikami, Yoshiki and Mukasa, Akitake},
title = {{Histological grade 2 and non-contrast-enhancing phenotype provide prognostic information complementary to DNA methylation classification in TERTp-mutant molecular glioblastomas}},
journal = {Acta neuropathologica communications},
year = {2026},
month = mar,
volume = {14},
number = {1},
pages = {88},
publisher = {BMC},
issn = {2051-5960},
doi = {10.1186/
url = {https://
pmid = {41781993},
pmcid = {PMC13069819}
}
RIS
TY - JOUR
AU - Sueyoshi, Hiroyuki
AU - Fujimoto, Kenji
AU - Fujita, Katsumi
AU - Tanaka, Kazuhito
AU - Inoue, Hirotaka
AU - Yamada, Rin
AU - Yamamoto, Takahiro
AU - Nakachi, Yutaka
AU - Kuroda, Jun-ichiro
AU - Shinojima, Naoki
AU - Iwamoto, Kazuya
AU - Mikami, Yoshiki
AU - Mukasa, Akitake
TI - Histological grade 2 and non-contrast-enhancing phenotype provide prognostic information complementary to DNA methylation classification in TERTp-mutant molecular glioblastomas
T2 - Acta neuropathologica communications
J2 - Acta Neuropathol Commun
PY - 2026
DA - 2026/
VL - 14
IS - 1
SP - 88
SN - 2051-5960
PB - BMC
DO - 10.1186/
UR - https://
LA - en
ER -
CSL-JSON
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