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A federated multimodal deep learning framework for brain tumor classification using MRI.

Overview

Authors: K Lakshmi Vasanthi1, J Sree Darshne1, Pattabiraman Venkatasubbu1, Parvathi Ramasubramanian2
  1. School of Computer Science Engineering, Vellore Institute of Technology, Chennai, India
  2. Centre for Advanced Data Science, Vellore Institute of Technology, Chennai, India
Journal: Frontiers in artificial intelligence, volume 9, article 1754000
Dates: received 25 November 2025; accepted 9 March 2026; published online 30 March 2026
Type: Research article · Language: English
License: CC BY
Identifiers: DOI 10.3389/frai.2026.1754000 · PMID 41982753 · PMCID PMC13071016 · OpenAlex W7143400094
Open access: gold, a free copy (OpenAlex)
Categories: structural MRI / diffusion (modality), other condition (population), methods / tools (subfield)
Methods: Statistics, Machine learning
Keywords: brain tumor classification, deep learning, differential privacy, federated learning, medical image analysis, prototype aggregation, secure aggregation
Topic: Privacy-Preserving Technologies in Data (Artificial Intelligence, Computer Science), according to OpenAlex
Citations: not cited yet (Europe PMC); 26 references in the paper

Abstract

Introduction: Brain tumor classification using MRI plays a critical role in early diagnosis and treatment planning. However, traditional centralized approaches require sharing sensitive medical data, which raises serious privacy concerns. Additionally, the distribution of data across multiple hospitals limits effective model training and utilization. Therefore, there is a strong need for privacy-preserving and distributed learning methods that ensure both security and accuracy in classification.

Methods: In this work, a federated learning framework is proposed to enable collaborative model training without sharing raw data. To improve efficiency, a layer skipping mechanism is applied, which reduces communication cost during training. The FedPropSAG aggregation method is used to enhance convergence and overall model performance. Furthermore, Differential Privacy (DP) and Secure Aggregation (SA) techniques are incorporated to ensure data privacy and secure communication.

Results: The proposed model achieves high classification accuracy across distributed datasets, demonstrating its effectiveness. The communication cost is significantly reduced due to the implementation of the layer skipping mechanism. The model performs well even under non-IID data distributions, which are common in real-world scenarios. Importantly, the integration of privacy-preserving techniques does not degrade the overall model performance.

Discussion: The proposed approach provides an efficient and scalable solution for distributed medical data analysis. It ensures patient data privacy while still enabling collaborative learning across multiple institutions. The reduction in communication overhead makes the framework suitable for practical deployment in healthcare systems. Overall, the model successfully balances accuracy, efficiency, and privacy, making it a strong candidate for real-world applications.

Reproduced under the paper's license (CC BY), from the paper cited above.

Code

The paper links to its data and to no code of its authors: see the Data section.

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Data

Datasets cited

Data availability statement

Publicly available datasets were analyzed in this study. This data can be found at: https://www.kaggle.com/datasets/masoudnickparvar/brain-tumor-mri-dataset.

Reproduced under the paper's license (CC BY), from the paper cited above.

Versions

The history of this record: each version stored by the harvester or made by a correction of its authors or of the maintainers of its code, and what changed in its facts. The texts of the paper (its abstract, its availability statements) are not part of it; versions that changed only those are not listed.

Version 1, 30 September 2026: the first record

Recorded: type, language, journal, volume, pages, dates, 4 authors, 7 keywords, 25 references.

Cite

This paper

Lakshmi Vasanthi, K., Sree Darshne, J., Venkatasubbu, P., & Ramasubramanian, P. (2026). A federated multimodal deep learning framework for brain tumor classification using MRI. Frontiers in artificial intelligence, 9, 1754000. https://doi.org/10.3389/frai.2026.1754000

BibTeX

@article{lakshmivasanthi2026federated,
author = {Lakshmi Vasanthi, K and Sree Darshne, J and Venkatasubbu, Pattabiraman and Ramasubramanian, Parvathi},
title = {{A federated multimodal deep learning framework for brain tumor classification using MRI}},
journal = {Frontiers in artificial intelligence},
year = {2026},
month = mar,
volume = {9},
pages = {1754000},
publisher = {Frontiers Media SA},
issn = {2624-8212},
doi = {10.3389/frai.2026.1754000},
url = {https://doi.org/10.3389/frai.2026.1754000},
pmid = {41982753},
pmcid = {PMC13071016}
}

RIS

TY - JOUR
AU - Lakshmi Vasanthi, K
AU - Sree Darshne, J
AU - Venkatasubbu, Pattabiraman
AU - Ramasubramanian, Parvathi
TI - A federated multimodal deep learning framework for brain tumor classification using MRI
T2 - Frontiers in artificial intelligence
J2 - Front Artif Intell
PY - 2026
DA - 2026/03/30
VL - 9
SP - 1754000
SN - 2624-8212
PB - Frontiers Media SA
DO - 10.3389/frai.2026.1754000
UR - https://doi.org/10.3389/frai.2026.1754000
LA - en
ER -

CSL-JSON

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