OSCR

High-to-Low Spectral Mapping for Cross-System Feature Adaptation in Medical Hyperspectral Imaging.

Overview

  1. Fundación Canaria Instituto de Investigación Sanitaria de Canarias (FIISC), 35012 Las Palmas de Gran Canaria, Spain
  2. Research Unit, Hospital Universitario de Gran Canaria Dr. Negrín, 35010 Las Palmas de Gran Canaria, Spain
  3. Institute for Applied Microelectronics (IUMA), Universidad de Las Palmas de Gran Canaria, 35001 Las Palmas de Gran Canaria, Spain(C.V.); (R.L.);(G.M.C.)
  4. Instituto de Investigación Sanitaria de Canarias (IISC), 35012 Las Palmas de Gran Canaria, Spain
  5. Department of Electrical Engineering, Eindhoven University of Technology (TU/e), 5612 Eindhoven, The Netherlands(F.M.); (S.Z.)
  6. Department of Neurosurgery, Hospital Universitario de Gran Canaria Dr. Negrín, 35010 Las Palmas de Gran Canaria, Spain(J.M.M.); (J.F.P.)
  7. Department of Neurosurgery, Hospital Universitario 12 Octubre, 28041 Madrid, Spain(A.L.); (L.J.-R.)
  8. Department of Surgery, Medicine Faculty, Universidad Complutense de Madrid, 28040 Madrid, Spain
  9. Instituto de Investigaciones Sanitarias (imas12), 28041 Madrid, Spain
Journal: Bioengineering (Basel, Switzerland), volume 13, issue 5, article 549
Dates: received 13 March 2026; accepted 8 May 2026; published online 13 May 2026
Type: Research article · Language: English
License: CC BY
Identifiers: DOI 10.3390/bioengineering13050549 · PMID 42194306 · PMCID PMC13203705 · OpenAlex W7161697023
Open access: gold, a free copy (OpenAlex)
Status: code verified
Categories: other condition (population), methods / tools (subfield)
Methods: Statistics, Machine learning, fMRI & imaging
Keywords: hyperspectral imaging, data mapping, feature adaptation, neurosurgery, brain cancer
Topic: Optical Imaging and Spectroscopy Techniques (Radiology, Nuclear Medicine and Imaging, Medicine), according to OpenAlex
Funding: Asociación Española Contra el Cáncer (PRDLP246561SANT); Agencia Canaria de Investigación, Innovación y Sociedad de la Información (TESIS2022010095); European Commission (101137416)
Citations: not cited yet (Europe PMC); 43 references in the paper

Abstract

Hyperspectral (HS) imaging has proven to be a promising intraoperative tool for tissue discrimination. However, obtaining representative datasets for intraoperative imaging remains challenging due to the complexity of surgical workflows and the sensitivity of the operating environments. Hence, developing new methods for cross-system feature adaptation could address this limitation. This work proposes a method for mapping high-resolution spectral data into lower-resolution sensor-conditioned domains, generating synthetic HS data that replicate the spectral features of the target system. We assessed the mapped data using public HS datasets and quantified spectral similarities using different metrics. Additionally, we evaluated the method with a HS classification framework for an intraoperative brain tumour classification problem. Results demonstrate that the synthetic data achieve high spectral alignment to original and actual data, captured with the target system. The brain tumour classification results show comparable performance between data modalities. Overall, this work provides a way to adapt existing HS datasets to complement newly acquired data, accelerating the development of artificial intelligence algorithms. This is particularly relevant in medical research, and especially in neurosurgery, where the complexity of acquisition environments limits the collection of large datasets.

Reproduced under the paper's license (CC BY), from the paper cited above.

Code

No file of the authors' code could be read here: it is described below, and read at its source.

git.iuma.ulpgc.es/stratum/public

License: none: the authors keep all their rights
State: the link answers, verified on 28 September 2026
Evidence: the link answers
Software Heritage: not checked
Found in: “Data Availability Statement”
Not found: README, license file, CITATION.cff, environment file, tests, continuous integration, documentation
Availability: 1 check, the latest on 28 September 2026: the link answers (HTTP 200)
  • 28 September 2026: the link answers (HTTP 200)

The paper's code and data availability statement is in the Data section.

Tracing map

Proposed by the machine: these links were found in the paper and verified at the source, without human review. The map will receive a Zenodo DOI once one of the paper's authors has validated it with their ORCID.

What the map holds:

  • 1 repository of the authors' code, each at its verified commit, with its license and how the link was found in the paper;
  • 0 scripts, each with its path and the digest of its content;
  • no match between paragraphs and code yet;
  • neither the text of the paper nor the code itself.

Its JSON (tracing-map.json) is deposited on Zenodo with its DOI once the map is validated.

Data

No dataset and no data link were found in the paper.

Data Availability Statement

The data presented in this study are available in the IUMA-ULPGC HSI Database and HSI Human Brain Database at https://hsidatabase.iuma.ulpgc.es/ (accessed on 1 March 2026) and https://hsibraindatabase.iuma.ulpgc.es/ (accessed on 1 March 2026). Additionally, the code and example data underlying this research can be found here: https://git.iuma.ulpgc.es:8300/stratum/public/high-to-low-spectral-mapping-for-cross-system-feature-adaptation/-/tree/5e29c790d2b410663d583eaf814e19f3e4faf7e3/ (accessed on 1 March 2026).

Reproduced under the paper's license (CC BY), from the paper cited above.

Versions

The history of this record: each version stored by the harvester or made by a correction of its authors or of the maintainers of its code, and what changed in its facts. The texts of the paper (its abstract, its availability statements) are not part of it; versions that changed only those are not listed.

Version 1, 28 September 2026: the first record

Recorded: type, language, journal, volume, issue, pages, dates, 12 authors, 5 keywords, 3 funders, 34 references.

Cite

This paper

Santana-Nunez, J., Verbers, M., Vega, C., Manni, F., Leon, R., Morera Molina, J., F Piñeiro, J., Lagares, A., Jimenez-Roldan, L., Callico, G. M., Zinger, S., & Fabelo, H. (2026). High-to-Low Spectral Mapping for Cross-System Feature Adaptation in Medical Hyperspectral Imaging. Bioengineering (Basel, Switzerland), 13(5), 549. https://doi.org/10.3390/bioengineering13050549

BibTeX

@article{santananunez2026high,
author = {Santana-Nunez, Javier and Verbers, Max and Vega, Carlos and Manni, Francesca and Leon, Raquel and Morera Molina, Jesús and F Piñeiro, Juan and Lagares, Alfonso and Jimenez-Roldan, Luis and Callico, Gustavo M and Zinger, Svitlana and Fabelo, Himar},
title = {{High-to-Low Spectral Mapping for Cross-System Feature Adaptation in Medical Hyperspectral Imaging}},
journal = {Bioengineering (Basel, Switzerland)},
year = {2026},
month = may,
volume = {13},
number = {5},
pages = {549},
publisher = {Multidisciplinary Digital Publishing Institute (MDPI)},
issn = {2306-5354},
doi = {10.3390/bioengineering13050549},
url = {https://doi.org/10.3390/bioengineering13050549},
pmid = {42194306},
pmcid = {PMC13203705}
}

RIS

TY - JOUR
AU - Santana-Nunez, Javier
AU - Verbers, Max
AU - Vega, Carlos
AU - Manni, Francesca
AU - Leon, Raquel
AU - Morera Molina, Jesús
AU - F Piñeiro, Juan
AU - Lagares, Alfonso
AU - Jimenez-Roldan, Luis
AU - Callico, Gustavo M
AU - Zinger, Svitlana
AU - Fabelo, Himar
TI - High-to-Low Spectral Mapping for Cross-System Feature Adaptation in Medical Hyperspectral Imaging
T2 - Bioengineering (Basel, Switzerland)
J2 - Bioengineering (Basel)
PY - 2026
DA - 2026/05/13
VL - 13
IS - 5
SP - 549
SN - 2306-5354
PB - Multidisciplinary Digital Publishing Institute (MDPI)
DO - 10.3390/bioengineering13050549
UR - https://doi.org/10.3390/bioengineering13050549
LA - en
ER -

CSL-JSON

{
"id": "10.3390/bioengineering13050549",
"type": "article-journal",
"title": "High-to-Low Spectral Mapping for Cross-System Feature Adaptation in Medical Hyperspectral Imaging",
"container-title": "Bioengineering (Basel, Switzerland)",
"author": [
{
"family": "Santana-Nunez",
"given": "Javier"
},
{
"family": "Verbers",
"given": "Max"
},
{
"family": "Vega",
"given": "Carlos"
},
{
"family": "Manni",
"given": "Francesca"
},
{
"family": "Leon",
"given": "Raquel"
},
{
"family": "Morera Molina",
"given": "Jesús"
},
{
"family": "F Piñeiro",
"given": "Juan"
},
{
"family": "Lagares",
"given": "Alfonso"
},
{
"family": "Jimenez-Roldan",
"given": "Luis"
},
{
"family": "Callico",
"given": "Gustavo M"
},
{
"family": "Zinger",
"given": "Svitlana"
},
{
"family": "Fabelo",
"given": "Himar"
}
],
"container-title-short": "Bioengineering (Basel)",
"volume": "13",
"issue": "5",
"page": "549",
"DOI": "10.3390/bioengineering13050549",
"PMID": "42194306",
"PMCID": "PMC13203705",
"ISSN": "2306-5354",
"publisher": "Multidisciplinary Digital Publishing Institute (MDPI)",
"URL": "https://doi.org/10.3390/bioengineering13050549",
"language": "en",
"issued": {
"date-parts": [
[
2026,
5,
13
]
]
}
}

The tracing map gets a citation of its own once an author has validated it and it has a DOI.

Similar papers

The papers with a page that share the most with this one: the tools found in their code, their categories, datasets, cited references and authors, the rarest counting most.

[1] doi:10.3389/fncir.2026.1814667 [code]
A modular and flexible pipeline for intraoperative electrode reconstruction and localization in patients with brain lesions.
Journal: Frontiers in neural circuits
In common: methods / tools, other condition, 1 reference
[2] doi:10.3390/diagnostics16152407
BG-YOLO11s: Boundary-Guided YOLO11 with Bézier Contour Augmentation for Brain Tumour Segmentation in T1-CE MRI.
Journal: Diagnostics (Basel, Switzerland)
In common: methods / tools, other condition, 1 reference
[3] doi:10.1126/sciadv.aeb1237
Magnetically actuated nanoantennas for wireless glioblastoma therapy.
Journal: Science advances
In common: other condition, 1 reference
[4] doi:10.1038/s41467-026-76587-0 [code]
Uncovering the signaling networks of disseminated glioblastoma cells in vivo with INSIGHT.
Journal: Nature communications
In common: other condition, 1 reference
[5] doi:10.1186/s40478-026-02312-z
Dissecting acute neuronal responses to glioblastoma using a dual-interface human iPSC neuronal culture platform.
Journal: Acta neuropathologica communications
In common: other condition, 1 reference
[6] doi:10.1002/adhm.202504842
Flash Assembloids: A Rapid Biofabrication of a Platform for Modeling Early Glioblastoma Invasion at the Glioblastoma-Brain Organoid Interfaces.
Journal: Advanced healthcare materials
In common: other condition, 1 reference
[7] doi:10.1080/10717544.2026.2660007
Angiopep-2-decorated bacterial outer membrane vesicles penetrate the blood-brain barrier for glioblastoma chemo-immunotherapy.
Journal: Drug delivery
In common: other condition, 1 reference
[8] doi:10.1186/s12935-026-04370-8
Machine learning-based prognostic model and single-cell transcriptomic integration for identifying brain metastasis-associated malignant subpopulations and potential therapeutic targets in lung adenocarcinoma.
Journal: Cancer cell international
In common: other condition, 1 reference
[9] doi:10.3390/cancers18132092
TGFB2 as a Prognostic Biomarker Associated with Myeloid-Enriched, Multi-Checkpoint-Activated Immunosuppression in Diffuse Glioma: A Multi-Cohort Transcriptomic Study.
Journal: Cancers
In common: other condition, 1 reference
[10] doi:10.1186/s13244-026-02296-3 [code]
A pre-trained foundation model framework for multiplanar MRI classification of extramural vascular invasion and mesorectal fascia invasion in rectal cancer.
Journal: Insights into imaging
In common: other condition, 1 reference

Contribute

The authors of this paper can claim it, correct its record and validate its tracing map, and the maintainers of its code (its owner, or a public member of its organization) correct what it says of their repository; anyone signed in can ask for its removal. Every request goes to OSCR's own machine, which answers it; your account page follows them.

Sign in with ORCID to claim this paper as one of its authors, correct its record or validate its tracing map: when the paper's metadata lists your ORCID iD, you are recognized at once. Maintainers of its code: sign in with GitHub, then claim the repository on your account page.

Request its removal

To ask OSCR to remove this record, the copies of its authors' scripts or its tracing map, use the removal request page: signed in, you say who you are, what to remove and why, then review and confirm the request. Published rules decide every request (how).

Discussion, reproductions, activity

Discussion: questions and error reports about this paper and its code, from signed-in readers and its authors. It opens with sign-in.

Reproductions: reports from readers who ran the authors' code: what they reproduced, with which environment, commit and data. It opens with sign-in.

Activity: what happens around this paper: new versions of its record, its map's validation, discussions and reproductions. It opens with sign-in.